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UniProtKB - O51970 (O51970_HALSA)

Entry version 150 (12 Aug 2020)
Sequence version 1 (01 Jun 1998)
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Protein
Submitted name:

Htr-like protein

Gene

htlD

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Htr-like proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:htlDImported
Ordered Locus Names:VNG_6035GImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates if the gene coding for the protein originates from the hydrogenosome, the mitochondrion, the nucleomorph, different plastids or a plasmid. The absence of this section means that the gene is located in one of the main chromosomal element(s).<p><a href='/help/encoded_on' target='_top'>More...</a></p>Encoded oniPlasmid pNRC100Imported
Plasmid pNRC200Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri64091 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Halobacteriaceae › Halobacterium ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000554 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componentsi: Plasmid pNRC100, Plasmid pNRC200

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1454-aspartylphosphatePROSITE-ProRule annotation1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

PhosphoproteinPROSITE-ProRule annotationARBA annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini94 – 210Response regulatoryInterPro annotationAdd BLAST117
Domaini221 – 275PASInterPro annotationAdd BLAST55
Domaini362 – 411PASInterPro annotationAdd BLAST50
Domaini587 – 657PASInterPro annotationAdd BLAST71
Domaini661 – 712PACInterPro annotationAdd BLAST52
Domaini723 – 910Histidine kinaseInterPro annotationAdd BLAST188

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili322 – 352Sequence analysisAdd BLAST31

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000445_114_58_2

Identification of Orthologs from Complete Genome Data

More...OMAi		AHERMDT

Database of Orthologous Groups

More...OrthoDBi		16486at2157

Family and domain databases

Conserved Domains Database

More...CDDi		cd00082, HisKA, 1 hit
cd00130, PAS, 4 hits
cd00156, REC, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.30.565.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR001610, PAC
IPR000014, PAS
IPR000700, PAS-assoc_C
IPR035965, PAS-like_dom_sf
IPR013656, PAS_4
IPR013767, PAS_fold
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF00989, PAS, 1 hit
PF08448, PAS_4, 2 hits
PF13426, PAS_9, 1 hit
PF00072, Response_reg, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00344, BCTRLSENSOR

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00086, PAC, 4 hits
SM00091, PAS, 4 hits
SM00448, REC, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55785, SSF55785, 4 hits
SSF55874, SSF55874, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00229, sensory_box, 4 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50109, HIS_KIN, 1 hit
PS50113, PAC, 1 hit
PS50112, PAS, 3 hits
PS50110, RESPONSE_REGULATORY, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O51970-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTNAWLSSSV VSAEQQLTPT RTTALSVAQM RLVATESISM DRVEFLGFTL 
        60         70         80         90        100
LLRDISRLDR YSTGQYLKVP GYNHLVWRMA RTRNPGRGGG GSIQVLHVDD 
       110        120        130        140        150
EPDFADMAAE FLEREDDRLT VESATSASEG LDRLDEHDYD CIVSDYDMPG 
       160        170        180        190        200
MDGVEFLETV RKAYPNLPFI LFTGKGSEQV ASEAIAAGVN DYLQKGSGSE 
       210        220        230        240        250
VYELLGNRIT NHVERVRAQR KQQRHLDAIE TAQEGISILD EDEHFRYVNQ 
       260        270        280        290        300
SFADLYGYEP AEMIGEHWEL IYPDEEVQAI NEEVLSIVEE TGYWRGETTG 
       310        320        330        340        350
LRADDSTFIE AHTLSQTDEG GLICTARDIT EAQEQAQELE EVTQQYRTVV 
       360        370        380        390        400
EQSRAGIRIV QDGTVKFVND RLAEMLGYPK HELLGAPAEE IITSETEDIV 
       410        420        430        440        450
RRHHATRMQG EPAPDRYEVE VDTEAGDRLC VELSVARIQY AGKPASLSLI 
       460        470        480        490        500
RDITERKEGE QALERYAALF DNAPDATALV EYRDETPIIR DANPAFEALF 
       510        520        530        540        550
AGGDGDIVGQ DIDGVVASSD QVAEARTISQ QVQEGEPIQK ELTRETADGL 
       560        570        580        590        600
RTFDFRSVPV EDRETGEIES AFVIYPDITE RKAHRRELER YETLVEATAD 
       610        620        630        640        650
PMYMLDEEGR FTYVDDAMVE TTGYSEETLL GEHVSKVMEE DHVERGEQLI 
       660        670        680        690        700
ESLLSSGEKR GTFEMVIETA GGERFSTENH ISLLDGDGEF HGTAGVLRDI 
       710        720        730        740        750
TDRLERERQL KRERDRLDEF ASVVSHDLRN PLNVAEGRLE LAMENCESEH 
       760        770        780        790        800
HDSVAQSLDR MESLIDDVLS LARAGEAVGE TEPVELADLV EACWQTVETA 
       810        820        830        840        850
SAGLVVETET TIQADPSRLQ QLFENLLRNA VEHGGEDVTI TIGDLPDGFY 
       860        870        880        890        900
VEDDGQGIPE DERGNVLDAG YSTAADGTGL GLSIVREVAE AHGWEIEVTE 
       910 
SSDGGARFEI IGVQMEG
Length:917
Mass (Da):102,064
Last modified:June 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i57F25C786D7C3915
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF016485 Genomic DNA Translation: AAC82814.1
AE004438 Genomic DNA Translation: AAG20731.1

Protein sequence database of the Protein Information Resource

More...PIRi		T08247

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC82814; AAC82814; AAC82814
AAG20731; AAG20731; VNG_6035G

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hal:AAC82814.1
hal:VNG_6035G

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|64091.14.peg.2104

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF016485 Genomic DNA Translation: AAC82814.1
AE004438 Genomic DNA Translation: AAG20731.1
PIRiT08247

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		1449253

Genome annotation databases

EnsemblBacteriaiAAC82814; AAC82814; AAC82814
AAG20731; AAG20731; VNG_6035G
KEGGihal:AAC82814.1
hal:VNG_6035G
PATRICifig|64091.14.peg.2104

Phylogenomic databases

HOGENOMiCLU_000445_114_58_2
OMAiAHERMDT
OrthoDBi16486at2157

Family and domain databases

CDDicd00082, HisKA, 1 hit
cd00130, PAS, 4 hits
cd00156, REC, 1 hit
Gene3Di3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR011006, CheY-like_superfamily
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR005467, His_kinase_dom
IPR003661, HisK_dim/P
IPR036097, HisK_dim/P_sf
IPR001610, PAC
IPR000014, PAS
IPR000700, PAS-assoc_C
IPR035965, PAS-like_dom_sf
IPR013656, PAS_4
IPR013767, PAS_fold
IPR004358, Sig_transdc_His_kin-like_C
IPR001789, Sig_transdc_resp-reg_receiver
PfamiView protein in Pfam
PF02518, HATPase_c, 1 hit
PF00512, HisKA, 1 hit
PF00989, PAS, 1 hit
PF08448, PAS_4, 2 hits
PF13426, PAS_9, 1 hit
PF00072, Response_reg, 1 hit
PRINTSiPR00344, BCTRLSENSOR
SMARTiView protein in SMART
SM00387, HATPase_c, 1 hit
SM00388, HisKA, 1 hit
SM00086, PAC, 4 hits
SM00091, PAS, 4 hits
SM00448, REC, 1 hit
SUPFAMiSSF47384, SSF47384, 1 hit
SSF52172, SSF52172, 1 hit
SSF55785, SSF55785, 4 hits
SSF55874, SSF55874, 1 hit
TIGRFAMsiTIGR00229, sensory_box, 4 hits
PROSITEiView protein in PROSITE
PS50109, HIS_KIN, 1 hit
PS50113, PAC, 1 hit
PS50112, PAS, 3 hits
PS50110, RESPONSE_REGULATORY, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO51970_HALSA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O51970
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: August 12, 2020
This is version 150 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

PlasmidImported, Reference proteomeImported
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