Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Elongation factor Tu

Gene

tuf

Organism
Aquifex pyrophilus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi85 – 89GTPUniRule annotation5
Nucleotide bindingi140 – 143GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
OrganismiAquifex pyrophilus
Taxonomic identifieri2714 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000912851 – 405Elongation factor TuAdd BLAST405

Proteomic databases

PRIDEiO50293

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO50293
SMRiO50293
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 213tr-type GAdd BLAST204

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni64 – 68G2By similarity5
Regioni85 – 88G3By similarity4
Regioni140 – 143G4By similarity4
Regioni178 – 180G5By similarity3

Sequence similaritiesi

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

O50293-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKEKFERTK EHVNVGTIGH VDHGKSTLTS AITCVLAAGL VEGGKAKCFK
60 70 80 90 100
YEEIDKAPEE KERGITINIT HVEYETAKRH YAHVDCPGHA DYIKNMITGA
110 120 130 140 150
AQMDGAILVV SAADGPMPQT REHVLLARQV NVPYIVVFMN KCDMVDDEEL
160 170 180 190 200
LELVELEVRE LLSKYEYPGD EVPVIRGSAL GALQELEQNS PGKWVGSIKE
210 220 230 240 250
LLNAMDEYIP TPEREVDKPF LMPIEDVFSI SGRGTVVTGR VERGVLRPGD
260 270 280 290 300
EVEIVGLREE PLKTVATSIE MFRKVLDEAL PGDNIGVLLR GVGKDDVERG
310 320 330 340 350
QVLAQPGSVK AHRKFRAQVY VLSKEEGGRH TPFFVNYRPQ FYFRTADVTG
360 370 380 390 400
TVVKLPEGVE MVMPGDNVEL EVELIAPVAL EEGLRFAIRE GGRTVGAGVV

TKILD
Length:405
Mass (Da):44,672
Last modified:June 1, 1998 - v1
Checksum:i012A9CD9C60AA16C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y15787 Genomic DNA Translation: CAA75781.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y15787 Genomic DNA Translation: CAA75781.1

3D structure databases

ProteinModelPortaliO50293
SMRiO50293
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiO50293

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiEFTU_AQUPY
AccessioniPrimary (citable) accession number: O50293
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: June 1, 1998
Last modified: October 10, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again