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UniProtKB - O50008 (METE1_ARATH)

Entry version 168 (23 Feb 2022)
Sequence version 1 (01 Jun 1998)
Previous versions | rss
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Protein

5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1

Gene

MS1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+Note: Binds 2 Zn2+ ions per subunit.

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=60 µM for 5-methyltetrahydrofolate1 Publication
  1. Vmax=26.5 nmol/min/mg enzyme toward 5-methyltetrahydrofolate1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: L-methionine biosynthesis via de novo pathway

This protein is involved in step 1 of the subpathway that synthesizes L-methionine from L-homocysteine (MetE route). This subpathway is part of the pathway L-methionine biosynthesis via de novo pathway, which is itself part of Amino-acid biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-methionine from L-homocysteine (MetE route), the pathway L-methionine biosynthesis via de novo pathway and in Amino-acid biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei490L-homocysteine1
Binding sitei5675-methyltetrahydrofolate1 Publication1
Binding sitei605L-homocysteine1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi647Zinc 11
Metal bindingi649Zinc 11
Metal bindingi658Zinc 21
Metal bindingi662Zinc 21
Metal bindingi733Zinc 11

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processAmino-acid biosynthesis, Methionine biosynthesis
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		ARA:AT5G17920-MONOMER

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		2.1.1.14, 399

SABIO-RK: Biochemical Reaction Kinetics Database

More...SABIO-RKi		O50008

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00051;UER00082

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 (EC:2.1.1.14)
Alternative name(s):
Cobalamin-independent methionine synthase 1
Short name:
AtMS1
Vitamin-B12-independent methionine synthase 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MS1
Synonyms:CIMS
Ordered Locus Names:At5g17920
ORF Names:MPI7.9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

More...Araporti		AT5G17920

The Arabidopsis Information Resource

More...TAIRi		locus:2170318, AT5G17920

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000986961 – 7655-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1Add BLAST765

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O50008

PRoteomics IDEntifications database

More...PRIDEi		O50008

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		238988

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...SWISS-2DPAGEi		O50008

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O50008

MetOSite database of methionine sulfoxide sites

More...MetOSitei		O50008

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in leaves, stems, flowers, siliques and seeds.1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O50008, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O50008, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		16936, 14 interactors

Protein interaction database and analysis system

More...IntActi		O50008, 2 interactors

Molecular INTeraction database

More...MINTi		O50008

STRING: functional protein association networks

More...STRINGi		3702.AT5G17920.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1765
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O50008

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		O50008

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni437 – 439L-homocysteine binding3
Regioni521 – 5225-methyltetrahydrofolate binding2

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the vitamin-B12 independent methionine synthase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG2263, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_013175_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O50008

Identification of Orthologs from Complete Genome Data

More...OMAi		KVMKGML

Database of Orthologous Groups

More...OrthoDBi		237390at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O50008

Family and domain databases

Conserved Domains Database

More...CDDi		cd03311, CIMS_C_terminal_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		3.20.20.210, 2 hits

HAMAP database of protein families

More...HAMAPi		MF_00172, Meth_synth, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR013215, Cbl-indep_Met_Synth_N
IPR006276, Cobalamin-indep_Met_synthase
IPR002629, Met_Synth_C/arc
IPR038071, UROD/MetE-like_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF08267, Meth_synt_1, 1 hit
PF01717, Meth_synt_2, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF000382, MeTrfase_B12_ind, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF51726, SSF51726, 2 hits

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01371, met_syn_B12ind, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O50008-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASHIVGYPR MGPKRELKFA LESFWDGKST AEDLQKVSAD LRSSIWKQMS 
        60         70         80         90        100
AAGTKFIPSN TFAHYDQVLD TTAMLGAVPP RYGYTGGEIG LDVYFSMARG 
       110        120        130        140        150
NASVPAMEMT KWFDTNYHYI VPELGPEVNF SYASHKAVNE YKEAKALGVD 
       160        170        180        190        200
TVPVLVGPVS YLLLSKAAKG VDKSFELLSL LPKILPIYKE VITELKAAGA 
       210        220        230        240        250
TWIQLDEPVL VMDLEGQKLQ AFTGAYAELE STLSGLNVLV ETYFADIPAE 
       260        270        280        290        300
AYKTLTSLKG VTAFGFDLVR GTKTLDLVKA GFPEGKYLFA GVVDGRNIWA 
       310        320        330        340        350
NDFAASLSTL QALEGIVGKD KLVVSTSCSL LHTAVDLINE TKLDDEIKSW 
       360        370        380        390        400
LAFAAQKVVE VNALAKALAG QKDEALFSAN AAALASRRSS PRVTNEGVQK 
       410        420        430        440        450
AAAALKGSDH RRATNVSARL DAQQKKLNLP ILPTTTIGSF PQTVELRRVR 
       460        470        480        490        500
REYKAKKVSE EDYVKAIKEE IKKVVDLQEE LDIDVLVHGE PERNDMVEYF 
       510        520        530        540        550
GEQLSGFAFT ANGWVQSYGS RCVKPPVIYG DVSRPKAMTV FWSAMAQSMT 
       560        570        580        590        600
SRPMKGMLTG PVTILNWSFV RNDQPRHETC YQIALAIKDE VEDLEKGGIG 
       610        620        630        640        650
VIQIDEAALR EGLPLRKSEH AFYLDWAVHS FRITNCGVQD STQIHTHMCY 
       660        670        680        690        700
SHFNDIIHSI IDMDADVITI ENSRSDEKLL SVFREGVKYG AGIGPGVYDI 
       710        720        730        740        750
HSPRIPSSEE IADRVNKMLA VLEQNILWVN PDCGLKTRKY TEVKPALKNM 
       760 
VDAAKLIRSQ LASAK
Length:765
Mass (Da):84,357
Last modified:June 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2EA01908B5951154
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti270R → L in AAL09712 (PubMed:14593172).Curated1
Sequence conflicti282F → S in CAE55863 (PubMed:15024005).Curated1
Sequence conflicti295G → R in AAN31836 (PubMed:14593172).Curated1
Sequence conflicti351L → M in CAE55863 (PubMed:15024005).Curated1
Sequence conflicti442Q → R in AAN31836 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
U97200 mRNA Translation: AAC50037.1
AJ608673 mRNA Translation: CAE55863.1
AB011480 Genomic DNA Translation: BAB11226.1
CP002688 Genomic DNA Translation: AED92486.1
CP002688 Genomic DNA Translation: AED92487.1
AF370522 mRNA Translation: AAK43899.1
AY048201 mRNA Translation: AAK82464.1
AY056098 mRNA Translation: AAL06986.1
AY057478 mRNA Translation: AAL09712.1
AY057499 mRNA Translation: AAL09740.1
AY069876 mRNA Translation: AAL47432.1
AY070771 mRNA Translation: AAL50108.1
AY091692 mRNA Translation: AAM10291.1
BT000691 mRNA Translation: AAN31836.1

NCBI Reference Sequences

More...RefSeqi		NP_001078599.1, NM_001085130.2
NP_197294.1, NM_121798.4

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT5G17920.1; AT5G17920.1; AT5G17920
AT5G17920.2; AT5G17920.2; AT5G17920

Database of genes from NCBI RefSeq genomes

More...GeneIDi		831660

Gramene; a comparative resource for plants

More...Gramenei		AT5G17920.1; AT5G17920.1; AT5G17920
AT5G17920.2; AT5G17920.2; AT5G17920

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ath:AT5G17920

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U97200 mRNA Translation: AAC50037.1
AJ608673 mRNA Translation: CAE55863.1
AB011480 Genomic DNA Translation: BAB11226.1
CP002688 Genomic DNA Translation: AED92486.1
CP002688 Genomic DNA Translation: AED92487.1
AF370522 mRNA Translation: AAK43899.1
AY048201 mRNA Translation: AAK82464.1
AY056098 mRNA Translation: AAL06986.1
AY057478 mRNA Translation: AAL09712.1
AY057499 mRNA Translation: AAL09740.1
AY069876 mRNA Translation: AAL47432.1
AY070771 mRNA Translation: AAL50108.1
AY091692 mRNA Translation: AAM10291.1
BT000691 mRNA Translation: AAN31836.1
RefSeqiNP_001078599.1, NM_001085130.2
NP_197294.1, NM_121798.4

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1U1HX-ray2.55A1-765[»]
1U1JX-ray2.40A1-765[»]
1U1UX-ray2.95A1-765[»]
1U22X-ray2.65A1-765[»]
SMRiO50008
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi16936, 14 interactors
IntActiO50008, 2 interactors
MINTiO50008
STRINGi3702.AT5G17920.1

PTM databases

iPTMnetiO50008
MetOSiteiO50008

2D gel databases

SWISS-2DPAGEiO50008

Proteomic databases

PaxDbiO50008
PRIDEiO50008
ProteomicsDBi238988

Genome annotation databases

EnsemblPlantsiAT5G17920.1; AT5G17920.1; AT5G17920
AT5G17920.2; AT5G17920.2; AT5G17920
GeneIDi831660
GrameneiAT5G17920.1; AT5G17920.1; AT5G17920
AT5G17920.2; AT5G17920.2; AT5G17920
KEGGiath:AT5G17920

Organism-specific databases

AraportiAT5G17920
TAIRilocus:2170318, AT5G17920

Phylogenomic databases

eggNOGiKOG2263, Eukaryota
HOGENOMiCLU_013175_0_0_1
InParanoidiO50008
OMAiKVMKGML
OrthoDBi237390at2759
PhylomeDBiO50008

Enzyme and pathway databases

UniPathwayiUPA00051;UER00082
BioCyciARA:AT5G17920-MONOMER
BRENDAi2.1.1.14, 399
SABIO-RKiO50008

Miscellaneous databases

EvolutionaryTraceiO50008

Protein Ontology

More...PROi		PR:O50008

Gene expression databases

ExpressionAtlasiO50008, baseline and differential
GenevisibleiO50008, AT

Family and domain databases

CDDicd03311, CIMS_C_terminal_like, 1 hit
Gene3Di3.20.20.210, 2 hits
HAMAPiMF_00172, Meth_synth, 1 hit
InterProiView protein in InterPro
IPR013215, Cbl-indep_Met_Synth_N
IPR006276, Cobalamin-indep_Met_synthase
IPR002629, Met_Synth_C/arc
IPR038071, UROD/MetE-like_sf
PfamiView protein in Pfam
PF08267, Meth_synt_1, 1 hit
PF01717, Meth_synt_2, 1 hit
PIRSFiPIRSF000382, MeTrfase_B12_ind, 1 hit
SUPFAMiSSF51726, SSF51726, 2 hits
TIGRFAMsiTIGR01371, met_syn_B12ind, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMETE1_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O50008
Secondary accession number(s): Q6KCR2, Q8H162, Q93ZK3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: June 1, 1998
Last modified: February 23, 2022
This is version 168 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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