UniProtKB - O49841 (RAC2A_ARATH)
Protein
Ras-related protein RABC2a
Gene
RABC2A
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Intracellular vesicle trafficking and protein transport.By similarity
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 20 – 27 | GTPBy similarity | 8 | |
Nucleotide bindingi | 67 – 71 | GTPBy similarity | 5 | |
Nucleotide bindingi | 127 – 130 | GTPBy similarity | 4 | |
Nucleotide bindingi | 157 – 158 | GTPBy similarity | 2 |
GO - Molecular functioni
- GTPase activity Source: GO_Central
- GTP binding Source: UniProtKB-KW
- GTP-dependent protein binding Source: TAIR
- myosin XI tail binding Source: TAIR
GO - Biological processi
- intracellular protein transport Source: GO_Central
Keywordsi
Biological process | Protein transport, Transport |
Ligand | GTP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Ras-related protein RABC2aShort name: AtRABC2a Alternative name(s): Ras-related protein Rab18B Short name: AtRab18B |
Gene namesi | Name:RABC2A Synonyms:RAB18B Ordered Locus Names:At5g03530 ORF Names:F12E4.310 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT5G03530 |
TAIRi | locus:2831859, AT5G03530 |
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Lipid-anchor Curated; Cytoplasmic side Curated
Other locations
- Cytoplasm 1 Publication
Note: Colocalizes with peroxisome.
Peroxisome
- peroxisome Source: TAIR
Plasma Membrane
- plasma membrane Source: TAIR
Other locations
- endomembrane system Source: GO_Central
Keywords - Cellular componenti
Cell membrane, Cytoplasm, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000407358 | 1 – 210 | Ras-related protein RABC2aAdd BLAST | 210 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Lipidationi | 208 | S-geranylgeranyl cysteineBy similarity | 1 | |
Lipidationi | 209 | S-geranylgeranyl cysteineBy similarity | 1 |
Keywords - PTMi
Lipoprotein, PrenylationProteomic databases
PaxDbi | O49841 |
PRIDEi | O49841 |
ProteomicsDBi | 236389 |
PTM databases
iPTMneti | O49841 |
Expressioni
Gene expression databases
ExpressionAtlasi | O49841, baseline and differential |
Genevisiblei | O49841, AT |
Interactioni
Subunit structurei
Interacts with XI-2/MYA2.
1 PublicationBinary interactionsi
O49841
With | #Exp. | IntAct |
---|---|---|
XI-2 [Q9LKB9] | 3 | EBI-2009559,EBI-2009528 |
GO - Molecular functioni
- GTP-dependent protein binding Source: TAIR
- myosin XI tail binding Source: TAIR
Protein-protein interaction databases
BioGRIDi | 17086, 1 interactor |
IntActi | O49841, 1 interactor |
STRINGi | 3702.AT5G03530.1 |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 41 – 49 | Effector regionBy similarity | 9 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | KOG0080, Eukaryota |
HOGENOMi | CLU_041217_10_1_1 |
InParanoidi | O49841 |
OMAi | SEPKFKL |
OrthoDBi | 1247169at2759 |
PhylomeDBi | O49841 |
Family and domain databases
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR025662, Sigma_54_int_dom_ATP-bd_1 IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51419, RAB, 1 hit PS00675, SIGMA54_INTERACT_1, 1 hit |
i Sequence
Sequence statusi: Complete.
O49841-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSSSGQSGY DLSFKILLIG DSGVGKSSLL VSFISSSVED LAPTIGVDFK
60 70 80 90 100
IKQLTVGGKR LKLTIWDTAG QERFRTLTSS YYRGAQGIIL VYDVTRRETF
110 120 130 140 150
TNLVDVWGKE IELYSTNQEC VRMLVGNKVD RESERGVSRE EGIALAKELN
160 170 180 190 200
CMFLECSART RQNVEQCFEE LALKIMEVPS LLEEGSSAVK RNILKQKPEH
210
QTNTQSGCCS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D89824 mRNA Translation: BAA24074.1 AL162751 Genomic DNA Translation: CAB83314.1 CP002688 Genomic DNA Translation: AED90619.1 CP002688 Genomic DNA Translation: ANM70568.1 AK119027 mRNA Translation: BAC43603.1 BT006101 mRNA Translation: AAP04086.1 |
PIRi | T48379 |
RefSeqi | NP_001332165.1, NM_001342711.1 NP_568121.1, NM_120433.3 |
Genome annotation databases
EnsemblPlantsi | AT5G03530.1; AT5G03530.1; AT5G03530 AT5G03530.2; AT5G03530.2; AT5G03530 |
GeneIDi | 831810 |
Gramenei | AT5G03530.1; AT5G03530.1; AT5G03530 AT5G03530.2; AT5G03530.2; AT5G03530 |
KEGGi | ath:AT5G03530 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D89824 mRNA Translation: BAA24074.1 AL162751 Genomic DNA Translation: CAB83314.1 CP002688 Genomic DNA Translation: AED90619.1 CP002688 Genomic DNA Translation: ANM70568.1 AK119027 mRNA Translation: BAC43603.1 BT006101 mRNA Translation: AAP04086.1 |
PIRi | T48379 |
RefSeqi | NP_001332165.1, NM_001342711.1 NP_568121.1, NM_120433.3 |
3D structure databases
SMRi | O49841 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 17086, 1 interactor |
IntActi | O49841, 1 interactor |
STRINGi | 3702.AT5G03530.1 |
PTM databases
iPTMneti | O49841 |
Proteomic databases
PaxDbi | O49841 |
PRIDEi | O49841 |
ProteomicsDBi | 236389 |
Genome annotation databases
EnsemblPlantsi | AT5G03530.1; AT5G03530.1; AT5G03530 AT5G03530.2; AT5G03530.2; AT5G03530 |
GeneIDi | 831810 |
Gramenei | AT5G03530.1; AT5G03530.1; AT5G03530 AT5G03530.2; AT5G03530.2; AT5G03530 |
KEGGi | ath:AT5G03530 |
Organism-specific databases
Araporti | AT5G03530 |
TAIRi | locus:2831859, AT5G03530 |
Phylogenomic databases
eggNOGi | KOG0080, Eukaryota |
HOGENOMi | CLU_041217_10_1_1 |
InParanoidi | O49841 |
OMAi | SEPKFKL |
OrthoDBi | 1247169at2759 |
PhylomeDBi | O49841 |
Miscellaneous databases
PROi | PR:O49841 |
Gene expression databases
ExpressionAtlasi | O49841, baseline and differential |
Genevisiblei | O49841, AT |
Family and domain databases
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR025662, Sigma_54_int_dom_ATP-bd_1 IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
PROSITEi | View protein in PROSITE PS51419, RAB, 1 hit PS00675, SIGMA54_INTERACT_1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RAC2A_ARATH | |
Accessioni | O49841Primary (citable) accession number: O49841 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 3, 2011 |
Last sequence update: | June 1, 1998 | |
Last modified: | December 2, 2020 | |
This is version 149 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families