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UniProtKB - O49549 (O49549_ARATH)

Entry version 120 (31 Jul 2019)
Sequence version 2 (01 Nov 1998)
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Protein
Submitted name:

Uncharacterized protein F7J7.10

Gene

F7J7.10

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein F7J7.10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:F7J7.10Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		O49549

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		O49549 baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati4 – 38PPRPROSITE-ProRule annotationAdd BLAST35
Repeati39 – 73PPRPROSITE-ProRule annotationAdd BLAST35
Repeati74 – 100PPRPROSITE-ProRule annotationAdd BLAST27
Repeati106 – 136PPRPROSITE-ProRule annotationAdd BLAST31
Repeati142 – 172PPRPROSITE-ProRule annotationAdd BLAST31
Repeati208 – 242PPRPROSITE-ProRule annotationAdd BLAST35
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini381 – 419RING-typeInterPro annotationAdd BLAST39
Domaini926 – 1051PHD-typeInterPro annotationAdd BLAST126
Domaini1128 – 1209BRCTInterPro annotationAdd BLAST82
Domaini1230 – 1322BRCTInterPro annotationAdd BLAST93

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni452 – 893DisorderedSequence analysisAdd BLAST442

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1291 – 1311Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi462 – 500PolyampholyteSequence analysisAdd BLAST39
Compositional biasi514 – 535PolarSequence analysisAdd BLAST22
Compositional biasi536 – 561PolyampholyteSequence analysisAdd BLAST26
Compositional biasi570 – 584PolyampholyteSequence analysisAdd BLAST15
Compositional biasi585 – 607PolarSequence analysisAdd BLAST23
Compositional biasi608 – 624PolyampholyteSequence analysisAdd BLAST17
Compositional biasi689 – 728PolarSequence analysisAdd BLAST40
Compositional biasi742 – 759PolarSequence analysisAdd BLAST18
Compositional biasi800 – 822PolyampholyteSequence analysisAdd BLAST23
Compositional biasi838 – 853PolyampholyteSequence analysisAdd BLAST16
Compositional biasi854 – 878PolarSequence analysisAdd BLAST25
Compositional biasi879 – 893PolyampholyteSequence analysisAdd BLAST15

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PPR family. PCMP-H subfamily.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410ITQ6 Eukaryota
ENOG4111WR7 LUCA

Database of Orthologous Groups

More...OrthoDBi		1344243at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 2 hits
3.30.40.10, 2 hits
3.40.50.10190, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011364 BRCA1
IPR031099 BRCA1-associated
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR032867 DYW_dom
IPR034732 EPHD
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS

The PANTHER Classification System

More...PANTHERi		PTHR13763 PTHR13763, 1 hit
PTHR13763:SF0 PTHR13763:SF0, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00533 BRCT, 1 hit
PF16589 BRCT_2, 1 hit
PF14432 DYW_deaminase, 1 hit
PF01535 PPR, 4 hits

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF001734 BRCA1, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00292 BRCT, 2 hits
SM00184 RING, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52113 SSF52113, 2 hits

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR00756 PPR, 2 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50172 BRCT, 2 hits
PS51805 EPHD, 1 hit
PS51375 PPR, 6 hits
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

O49549-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
IKPDGFTIVS LLSACAKIGA LTLGKRVHVY MIKVGLTRNL HSSNVLLDLY 
        60         70         80         90        100
ARCGRVEEAK TLFDEMVDKN SVSWTSLIVG LAVNGFGKEA IELFKYMEST 
       110        120        130        140        150
EGLLPCEITF VGILYACSHC GMVKEGFEYF RRMREEYKIE PRIEHFGCMV 
       160        170        180        190        200
DLLARAGQVK KAYEYIKSMP MQPNVVIWRT LLGACTVHGD SDLAEFARIQ 
       210        220        230        240        250
ILQLEPNHSG DYVLLSNMYA SEQRWSDVQK IRKQMLRDGV KKVPGHSLVE 
       260        270        280        290        300
VGNRVHEFLM GDKSHPQSDA IYAKLKEMTG RLRSEGYVPQ ISNVYVDVEE 
       310        320        330        340        350
EEKENAVVYH SEKIAIAFML ISTPERSPIT VVKNLRVCAD CHLAIKLVSK 
       360        370        380        390        400
VYNREIVVRD RSRSKMADTS HLERMGRELK CPICLSLYNS AVSLSCNHVF 
       410        420        430        440        450
CNACIVKSMK MDATCPVCKI PYHRREIRGA PHMDSLVSIY KNMEDASGIK 
       460        470        480        490        500
LFVSQNNPSP SDKEKQVRDA SVEKASDKNR QGSRKGRASK RNEYGKTKEI 
       510        520        530        540        550
DVDAPGPIVM KPSSQTKKRV QLLQNLSAES LTKPTESVET AEKPKDYTEN 
       560        570        580        590        600
TVIRLDEHPS LNKEGNLSPF FWLRDEDDGE NSSQRTESDQ LLGTTPVNVP 
       610        620        630        640        650
SFSDLMDSDH ESPSKEDEQQ KPNPGDMFDS EMFEWTQRPC SPEILPSPVK 
       660        670        680        690        700
AKVLGRDEID LTQKKLPKVK VASSKCKNRK AGSARNTVAR RSIGVSQEDN 
       710        720        730        740        750
MESSAAATIS EQQDSRGTSG TIIRNDVNTD ENVKAKRATR SKAQSTRVQS 
       760        770        780        790        800
DLNVSNEADG KQGTKRKRSS IKSSPAHPIA GPNELSLGTE IVGKGDQDQA 
       810        820        830        840        850
HGPSDTHPEK RSPTEKPSLK KRGRKSNASS SLKDLSGKTQ KKTSEKKLKL 
       860        870        880        890        900
DSHMISSKAT QPHGNGILTA GLNQGGDKQD SRNNRKSTVG KDDHTMQVIE 
       910        920        930        940        950
KCSTINKSSS GGSAHLRRCN GSLTKKFTCA FCQCSEDTEA SGEMTHYYRG 
       960        970        980        990       1000
EPVSADFNGG SKVIHVHKNC AEWAPNVYFN DLTIVNLDVE LTRSRRISCS 
      1010       1020       1030       1040       1050
CCGLKGAALG CYNKSCKNSF HVTCAKLIPE CRWDNVSVAY IVEALYSPLH 
      1060       1070       1080       1090       1100
SSFNTFSYQQ VKFVMLCPLD ASIKLPCEEA NSKDRKCKRT PKEPLHSQPK 
      1110       1120       1130       1140       1150
QVSGKANIRE LHIKQFHGFS KKLVLSCSGL TVEEKTVIAE FAELSGVTIS 
      1160       1170       1180       1190       1200
KNWDSTVTHV IASINENGAC KRTLKFMMAI LEGKWILTID WIKACMKNTK 
      1210       1220       1230       1240       1250
YVSEEPYEIT MDVHGIREGP YLGRQRALKK KPKLFTGLKF YIMGDFELAY 
      1260       1270       1280       1290       1300
KGYLQDLIVA AGGTILRRRP VSSDDNEAST IVVFSVEPSK KKTLTQRRSD 
      1310       1320       1330 
AEALAKSARA RAASSSWVLD SIAGCQILVL I
Length:1,331
Mass (Da):148,109
Last modified:November 1, 1998 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1FD980FA6DB4B08D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL021960 Genomic DNA Translation: CAA17526.1

Protein sequence database of the Protein Information Resource

More...PIRi		T04938

Genome annotation databases

Ensembl plant genome annotation project

More...EnsemblPlantsi		AT4G21065.1; AT4G21065.1; AT4G21065

Gramene; a comparative resource for plants

More...Gramenei		AT4G21065.1; AT4G21065.1; AT4G21065

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL021960 Genomic DNA Translation: CAA17526.1
PIRiT04938

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PRIDEiO49549

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT4G21065.1; AT4G21065.1; AT4G21065
GrameneiAT4G21065.1; AT4G21065.1; AT4G21065

Phylogenomic databases

eggNOGiENOG410ITQ6 Eukaryota
ENOG4111WR7 LUCA
OrthoDBi1344243at2759

Gene expression databases

ExpressionAtlasiO49549 baseline and differential

Family and domain databases

Gene3Di1.25.40.10, 2 hits
3.30.40.10, 2 hits
3.40.50.10190, 2 hits
InterProiView protein in InterPro
IPR011364 BRCA1
IPR031099 BRCA1-associated
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR032867 DYW_dom
IPR034732 EPHD
IPR002885 Pentatricopeptide_repeat
IPR011990 TPR-like_helical_dom_sf
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR13763 PTHR13763, 1 hit
PTHR13763:SF0 PTHR13763:SF0, 1 hit
PfamiView protein in Pfam
PF00533 BRCT, 1 hit
PF16589 BRCT_2, 1 hit
PF14432 DYW_deaminase, 1 hit
PF01535 PPR, 4 hits
PIRSFiPIRSF001734 BRCA1, 6 hits
SMARTiView protein in SMART
SM00292 BRCT, 2 hits
SM00184 RING, 1 hit
SUPFAMiSSF52113 SSF52113, 2 hits
TIGRFAMsiTIGR00756 PPR, 2 hits
PROSITEiView protein in PROSITE
PS50172 BRCT, 2 hits
PS51805 EPHD, 1 hit
PS51375 PPR, 6 hits
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO49549_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O49549
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: November 1, 1998
Last modified: July 31, 2019
This is version 120 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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