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Entry version 127 (10 Apr 2019)
Sequence version 1 (01 Jun 1998)
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Protein

ACT domain-containing protein ACR3

Gene

ACR3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May bind amino acids.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • amino acid binding Source: TAIR

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ACT domain-containing protein ACR3Curated
Alternative name(s):
Protein ACT DOMAIN REPEATS 31 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ACR31 Publication
Ordered Locus Names:At1g76990Imported
ORF Names:F22K20.9Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT1G76990

The Arabidopsis Information Resource

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TAIRi
locus:2025317 AT1G76990

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004314571 – 453ACT domain-containing protein ACR3Add BLAST453

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
O49285

PRoteomics IDEntifications database

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PRIDEi
O49285

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O49285

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in roots, cotyledons, rosette and cauline leaves, sepals, style, and pedicels and tips of young developing siliques.1 Publication

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Down-regulated by abscisic acid (ABA).1 Publication

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
O49285 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O49285 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
3702.AT1G76990.3

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
O49285

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O49285

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini37 – 112ACT 1PROSITE-ProRule annotationAdd BLAST76
Domaini130 – 212ACT 2PROSITE-ProRule annotationAdd BLAST83
Domaini266 – 341ACT 3PROSITE-ProRule annotationAdd BLAST76
Domaini344 – 423ACT 4PROSITE-ProRule annotationAdd BLAST80

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHHT Eukaryota
ENOG410ZR0Z LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000239159

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O49285

Identification of Orthologs from Complete Genome Data

More...
OMAi
SDCTLVK

Database of Orthologous Groups

More...
OrthoDBi
514448at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O49285

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR040217 ACR1-12
IPR002912 ACT_dom

The PANTHER Classification System

More...
PANTHERi
PTHR31096 PTHR31096, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01842 ACT, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51671 ACT, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O49285-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKVYWPYFD PEYENLSSRI NPPSVSIDNT SCKECTLVKV DSMNKPGILL
60 70 80 90 100
EVVQVLTDLD LTITKAYISS DGGWFMDVFH VTDQQGNKVT DSKTIDYIEK
110 120 130 140 150
VLGPKGHASA SQNTWPGKRV GVHSLGDHTS IEIIARDRPG LLSEVSAVLA
160 170 180 190 200
DLNINVVAAE AWTHNRRIAC VLYVNDNATS RAVDDPERLS SMEEQLNNVL
210 220 230 240 250
RGCEEQDEKF ARTSLSIGST HVDRRLHQMF FADRDYEAVT KLDDSASCGF
260 270 280 290 300
EPKITVEHCE EKGYSVINVS CEDRPKLMFD IVCTLTDMQY IVFHATISSS
310 320 330 340 350
GSHASQEYFI RHKDGCTLDT EGEKERVVKC LEAAIHRRVS EGWSLELCAK
360 370 380 390 400
DRVGLLSEVT RILREHGLSV SRAGVTTVGE QAVNVFYVKD ASGNPVDVKT
410 420 430 440 450
IEALRGEIGH SMMIDFKNKV PSRKWKEEGQ AGTGGGWAKT SFFFGNLLEK

LLP
Length:453
Mass (Da):50,403
Last modified:June 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i398854A709EFBFA4
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AF528059 mRNA Translation: AAM93428.1
AC002291 Genomic DNA Translation: AAC00631.1
CP002684 Genomic DNA Translation: AEE35917.1
CP002684 Genomic DNA Translation: AEE35918.1
CP002684 Genomic DNA Translation: AEE35919.1
CP002684 Genomic DNA Translation: AEE35920.1
CP002684 Genomic DNA Translation: AEE35921.1
AF360322 mRNA Translation: AAK26032.1
AY113891 mRNA Translation: AAM44939.1
AK317369 mRNA Translation: BAH20041.1
AY087972 mRNA Translation: AAM65519.1

Protein sequence database of the Protein Information Resource

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PIRi
H96798

NCBI Reference Sequences

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RefSeqi
NP_001031289.1, NM_001036212.1
NP_001117608.1, NM_001124136.2
NP_565146.1, NM_106350.3
NP_849896.1, NM_179565.2
NP_849897.1, NM_179566.2

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
At.22030

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G76990.1; AT1G76990.1; AT1G76990
AT1G76990.2; AT1G76990.2; AT1G76990
AT1G76990.3; AT1G76990.3; AT1G76990
AT1G76990.4; AT1G76990.4; AT1G76990
AT1G76990.5; AT1G76990.5; AT1G76990

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
844035

Gramene; a comparative resource for plants

More...
Gramenei
AT1G76990.1; AT1G76990.1; AT1G76990
AT1G76990.2; AT1G76990.2; AT1G76990
AT1G76990.3; AT1G76990.3; AT1G76990
AT1G76990.4; AT1G76990.4; AT1G76990
AT1G76990.5; AT1G76990.5; AT1G76990

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G76990

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF528059 mRNA Translation: AAM93428.1
AC002291 Genomic DNA Translation: AAC00631.1
CP002684 Genomic DNA Translation: AEE35917.1
CP002684 Genomic DNA Translation: AEE35918.1
CP002684 Genomic DNA Translation: AEE35919.1
CP002684 Genomic DNA Translation: AEE35920.1
CP002684 Genomic DNA Translation: AEE35921.1
AF360322 mRNA Translation: AAK26032.1
AY113891 mRNA Translation: AAM44939.1
AK317369 mRNA Translation: BAH20041.1
AY087972 mRNA Translation: AAM65519.1
PIRiH96798
RefSeqiNP_001031289.1, NM_001036212.1
NP_001117608.1, NM_001124136.2
NP_565146.1, NM_106350.3
NP_849896.1, NM_179565.2
NP_849897.1, NM_179566.2
UniGeneiAt.22030

3D structure databases

ProteinModelPortaliO49285
SMRiO49285
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G76990.3

PTM databases

iPTMnetiO49285

Proteomic databases

PaxDbiO49285
PRIDEiO49285

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G76990.1; AT1G76990.1; AT1G76990
AT1G76990.2; AT1G76990.2; AT1G76990
AT1G76990.3; AT1G76990.3; AT1G76990
AT1G76990.4; AT1G76990.4; AT1G76990
AT1G76990.5; AT1G76990.5; AT1G76990
GeneIDi844035
GrameneiAT1G76990.1; AT1G76990.1; AT1G76990
AT1G76990.2; AT1G76990.2; AT1G76990
AT1G76990.3; AT1G76990.3; AT1G76990
AT1G76990.4; AT1G76990.4; AT1G76990
AT1G76990.5; AT1G76990.5; AT1G76990
KEGGiath:AT1G76990

Organism-specific databases

AraportiAT1G76990
TAIRilocus:2025317 AT1G76990

Phylogenomic databases

eggNOGiENOG410IHHT Eukaryota
ENOG410ZR0Z LUCA
HOGENOMiHOG000239159
InParanoidiO49285
OMAiSDCTLVK
OrthoDBi514448at2759
PhylomeDBiO49285

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O49285

Gene expression databases

ExpressionAtlasiO49285 baseline and differential
GenevisibleiO49285 AT

Family and domain databases

InterProiView protein in InterPro
IPR040217 ACR1-12
IPR002912 ACT_dom
PANTHERiPTHR31096 PTHR31096, 1 hit
PfamiView protein in Pfam
PF01842 ACT, 4 hits
PROSITEiView protein in PROSITE
PS51671 ACT, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiACR3_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O49285
Secondary accession number(s): Q8LA88
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 7, 2015
Last sequence update: June 1, 1998
Last modified: April 10, 2019
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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