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UniProtKB - O48850 (VA725_ARATH)
Protein
Vesicle-associated membrane protein 725
Gene
VAMP725
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Involved in the targeting and/or fusion of transport vesicles to their target membrane.
1 PublicationGO - Biological processi
- protein transport Source: UniProtKB-KW
- vesicle-mediated transport Source: InterPro
Keywordsi
Biological process | Protein transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Vesicle-associated membrane protein 7251 PublicationShort name: AtVAMP7251 Publication |
Gene namesi | Name:VAMP7251 Publication Ordered Locus Names:At2g32670Imported ORF Names:F24L7.19Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G32670 |
TAIRi | locus:2046367, AT2G32670 |
Subcellular locationi
Endosome
- Early endosome membrane 1 Publication; Single-pass type IV membrane protein By similarity
Plasma membrane
- Cell membrane 1 Publication; Single-pass type IV membrane protein By similarity
Endosome
- early endosome membrane Source: UniProtKB-SubCell
- endosome Source: TAIR
Plasma Membrane
- plasma membrane Source: TAIR
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 261 | CytoplasmicSequence analysisAdd BLAST | 261 | |
Transmembranei | 262 – 282 | Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 283 – 285 | VesicularSequence analysis | 3 |
Keywords - Cellular componenti
Cell membrane, Endosome, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000206758 | 1 – 285 | Vesicle-associated membrane protein 725Add BLAST | 285 |
Proteomic databases
PaxDbi | O48850 |
PRIDEi | O48850 |
ProteomicsDBi | 243255 |
Expressioni
Tissue specificityi
Expressed in flowers, leaves, stems and roots.1 Publication
Gene expression databases
ExpressionAtlasi | O48850, baseline and differential |
Genevisiblei | O48850, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 3174, 1 interactor |
STRINGi | 3702.AT2G32670.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 75 – 179 | LonginPROSITE-ProRule annotationAdd BLAST | 105 | |
Domaini | 195 – 255 | v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST | 61 |
Sequence similaritiesi
Belongs to the synaptobrevin family.Curated
Keywords - Domaini
Coiled coil, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0859, Eukaryota |
HOGENOMi | CLU_064620_1_0_1 |
InParanoidi | O48850 |
OMAi | NCEDSHP |
OrthoDBi | 1211929at2759 |
PhylomeDBi | O48850 |
Family and domain databases
CDDi | cd14824, Longin, 1 hit |
InterProi | View protein in InterPro IPR011012, Longin-like_dom_sf IPR010908, Longin_dom IPR001388, Synaptobrevin IPR042855, V_SNARE_CC |
Pfami | View protein in Pfam PF13774, Longin, 1 hit PF00957, Synaptobrevin, 1 hit |
PRINTSi | PR00219, SYNAPTOBREVN |
SMARTi | View protein in SMART SM01270, Longin, 1 hit |
SUPFAMi | SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS50859, LONGIN, 1 hit PS00417, SYNAPTOBREVIN, 1 hit PS50892, V_SNARE, 1 hit |
i Sequence
Sequence statusi: Complete.
O48850-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDRSVVPISL APFQFLLVFW IFLTSVHTNP NKQQKTVVSL SLWWNSKNRI
60 70 80 90 100
RGCVWFFFLL RVTRTMGQQN LIYSFVARGT VILVEYTEFK GNFTAVAAQC
110 120 130 140 150
LQKLPSSNNK FTYNCDGHTF NYLVENGFTY CVVAVESVGR QIPMAFLERV
160 170 180 190 200
KEDFNKRYGG GKATTAQANS LNREFGSKLK EHMQYCVDHP DEISKLAKVK
210 220 230 240 250
AQVTEVKGVM MENIEKVLDR GEKIELLVDK TENLRSQAQD FRTQGTKIRR
260 270 280
KMWFENMKIK LIVLGIIITL ILIIILSVCG GFKCT
Sequence cautioni
The sequence AAC04496 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC003974 Genomic DNA Translation: AAC04496.1 Different initiation. CP002685 Genomic DNA Translation: AEC08714.1 AK118318 mRNA Translation: BAC42934.1 BT006042 mRNA Translation: AAP06822.1 |
PIRi | T00801 |
RefSeqi | NP_180826.2, NM_128826.4 |
Genome annotation databases
EnsemblPlantsi | AT2G32670.1; AT2G32670.1; AT2G32670 |
GeneIDi | 817827 |
Gramenei | AT2G32670.1; AT2G32670.1; AT2G32670 |
KEGGi | ath:AT2G32670 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC003974 Genomic DNA Translation: AAC04496.1 Different initiation. CP002685 Genomic DNA Translation: AEC08714.1 AK118318 mRNA Translation: BAC42934.1 BT006042 mRNA Translation: AAP06822.1 |
PIRi | T00801 |
RefSeqi | NP_180826.2, NM_128826.4 |
3D structure databases
SMRi | O48850 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 3174, 1 interactor |
STRINGi | 3702.AT2G32670.1 |
Proteomic databases
PaxDbi | O48850 |
PRIDEi | O48850 |
ProteomicsDBi | 243255 |
Genome annotation databases
EnsemblPlantsi | AT2G32670.1; AT2G32670.1; AT2G32670 |
GeneIDi | 817827 |
Gramenei | AT2G32670.1; AT2G32670.1; AT2G32670 |
KEGGi | ath:AT2G32670 |
Organism-specific databases
Araporti | AT2G32670 |
TAIRi | locus:2046367, AT2G32670 |
Phylogenomic databases
eggNOGi | KOG0859, Eukaryota |
HOGENOMi | CLU_064620_1_0_1 |
InParanoidi | O48850 |
OMAi | NCEDSHP |
OrthoDBi | 1211929at2759 |
PhylomeDBi | O48850 |
Miscellaneous databases
PROi | PR:O48850 |
Gene expression databases
ExpressionAtlasi | O48850, baseline and differential |
Genevisiblei | O48850, AT |
Family and domain databases
CDDi | cd14824, Longin, 1 hit |
InterProi | View protein in InterPro IPR011012, Longin-like_dom_sf IPR010908, Longin_dom IPR001388, Synaptobrevin IPR042855, V_SNARE_CC |
Pfami | View protein in Pfam PF13774, Longin, 1 hit PF00957, Synaptobrevin, 1 hit |
PRINTSi | PR00219, SYNAPTOBREVN |
SMARTi | View protein in SMART SM01270, Longin, 1 hit |
SUPFAMi | SSF64356, SSF64356, 1 hit |
PROSITEi | View protein in PROSITE PS50859, LONGIN, 1 hit PS00417, SYNAPTOBREVIN, 1 hit PS50892, V_SNARE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | VA725_ARATH | |
Accessioni | O48850Primary (citable) accession number: O48850 Secondary accession number(s): Q8GXC1 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 17, 2003 |
Last sequence update: | May 10, 2005 | |
Last modified: | September 29, 2021 | |
This is version 147 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families