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Protein

Vesicle-associated membrane protein 725

Gene

VAMP725

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Involved in the targeting and/or fusion of transport vesicles to their target membrane.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-8856825 Cargo recognition for clathrin-mediated endocytosis

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle-associated membrane protein 7251 Publication
Short name:
AtVAMP7251 Publication
Gene namesi
Name:VAMP7251 Publication
Ordered Locus Names:At2g32670Imported
ORF Names:F24L7.19Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G32670
TAIRilocus:2046367 AT2G32670

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 261CytoplasmicSequence analysisAdd BLAST261
Transmembranei262 – 282Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini283 – 285VesicularSequence analysis3

Keywords - Cellular componenti

Cell membrane, Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002067581 – 285Vesicle-associated membrane protein 725Add BLAST285

Proteomic databases

PaxDbiO48850
PRIDEiO48850

Expressioni

Tissue specificityi

Expressed in flowers, leaves, stems and roots.1 Publication

Gene expression databases

ExpressionAtlasiO48850 differential
GenevisibleiO48850 AT

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi3174, 1 interactor
STRINGi3702.AT2G32670.1

Structurei

3D structure databases

ProteinModelPortaliO48850
SMRiO48850
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 179LonginPROSITE-ProRule annotationAdd BLAST105
Domaini195 – 255v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST61

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0859 Eukaryota
COG5143 LUCA
HOGENOMiHOG000042712
InParanoidiO48850
KOiK08511
OMAiNTFREML
OrthoDBiEOG09360NHL
PhylomeDBiO48850

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR010908 Longin_dom
IPR001388 Synaptobrevin
PfamiView protein in Pfam
PF13774 Longin, 1 hit
PF00957 Synaptobrevin, 1 hit
PRINTSiPR00219 SYNAPTOBREVN
SMARTiView protein in SMART
SM01270 Longin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS50859 LONGIN, 1 hit
PS00417 SYNAPTOBREVIN, 1 hit
PS50892 V_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

O48850-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRSVVPISL APFQFLLVFW IFLTSVHTNP NKQQKTVVSL SLWWNSKNRI
60 70 80 90 100
RGCVWFFFLL RVTRTMGQQN LIYSFVARGT VILVEYTEFK GNFTAVAAQC
110 120 130 140 150
LQKLPSSNNK FTYNCDGHTF NYLVENGFTY CVVAVESVGR QIPMAFLERV
160 170 180 190 200
KEDFNKRYGG GKATTAQANS LNREFGSKLK EHMQYCVDHP DEISKLAKVK
210 220 230 240 250
AQVTEVKGVM MENIEKVLDR GEKIELLVDK TENLRSQAQD FRTQGTKIRR
260 270 280
KMWFENMKIK LIVLGIIITL ILIIILSVCG GFKCT
Length:285
Mass (Da):32,691
Last modified:May 10, 2005 - v2
Checksum:iF8A28595547166EE
GO

Sequence cautioni

The sequence AAC04496 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC003974 Genomic DNA Translation: AAC04496.1 Different initiation.
CP002685 Genomic DNA Translation: AEC08714.1
AK118318 mRNA Translation: BAC42934.1
BT006042 mRNA Translation: AAP06822.1
PIRiT00801
RefSeqiNP_180826.2, NM_128826.4
UniGeneiAt.38037
At.66389

Genome annotation databases

EnsemblPlantsiAT2G32670.1; AT2G32670.1; AT2G32670
GeneIDi817827
GrameneiAT2G32670.1; AT2G32670.1; AT2G32670
KEGGiath:AT2G32670

Similar proteinsi

Entry informationi

Entry nameiVA725_ARATH
AccessioniPrimary (citable) accession number: O48850
Secondary accession number(s): Q8GXC1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 132 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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