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Protein
Submitted name:

Pregnancy-associated glycoprotein 10

Gene

PAG10

Organism
Bos taurus (Bovine)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei90PROSITE-ProRule annotation1
Active sitei271PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.089

Names & Taxonomyi

Protein namesi
Submitted name:
Pregnancy-associated glycoprotein 10Imported
Gene namesi
Name:PAG10Imported
OrganismiBos taurus (Bovine)Imported
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 15Sequence analysisAdd BLAST15
ChainiPRO_501308495316 – 381Sequence analysisAdd BLAST366

Keywords - PTMi

Disulfide bondSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO46498
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini72 – 378Peptidase A1InterPro annotationAdd BLAST307

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
HOGENOMiHOG000197681
HOVERGENiHBG000482
KOiK06002

Family and domain databases

Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR012848 Aspartic_peptidase_N
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF07966 A1_Propeptide, 1 hit
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 2 hits
PS51767 PEPTIDASE_A1, 1 hit

Sequencei

Sequence statusi: Complete.

O46498-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKWLGLLGLV ALSECMVIIP LRQMKTMRET LRERHLLTNF SEEHPYNLSQ
60 70 80 90 100
KAANDQNIIY HHPLRSYKDF SYIGNINIGT PPQEFQVLFD TGSSSLWVPS
110 120 130 140 150
IYCQSSSCYK HNSFVPCNSS TFKATNKIFN TNYTATSIKG YLVYDTVRIG
160 170 180 190 200
NLVSVAQPFG LSLKEFGFDD VPFDGILGLG YPRRTITGAN PIFDNLWKQG
210 220 230 240 250
VISEPVFAFY LSSQKENGSV VMFGGVNRAY YKGELNWVPV SQVGSWHINI
260 270 280 290 300
DSISMNGTVV ACKRGCQALL DTGTAFLRGP RGSVSKIQKL IHARPIDREH
310 320 330 340 350
VVSCQAIGTL PPAVFTINGI DYPVPAQAYI QSLSGYCFSN FLVRPQRVNE
360 370 380
SETWILGEVF LRLYFSVFDR GNNRIGLAPA V
Length:381
Mass (Da):42,586
Last modified:October 2, 2007 - v2
Checksum:i50A5F6C13F1B4F4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020512 mRNA Translation: AAC04683.2
RefSeqiNP_788794.2, NM_176621.3
UniGeneiBt.4115

Genome annotation databases

GeneIDi337904
KEGGibta:337904

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF020512 mRNA Translation: AAC04683.2
RefSeqiNP_788794.2, NM_176621.3
UniGeneiBt.4115

3D structure databases

ProteinModelPortaliO46498
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiA01.089

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi337904
KEGGibta:337904

Organism-specific databases

CTDi337904

Phylogenomic databases

eggNOGiKOG1339 Eukaryota
ENOG410XNV7 LUCA
HOGENOMiHOG000197681
HOVERGENiHBG000482
KOiK06002

Family and domain databases

Gene3Di2.40.70.10, 2 hits
InterProiView protein in InterPro
IPR001461 Aspartic_peptidase_A1
IPR001969 Aspartic_peptidase_AS
IPR012848 Aspartic_peptidase_N
IPR033121 PEPTIDASE_A1
IPR021109 Peptidase_aspartic_dom_sf
PANTHERiPTHR13683 PTHR13683, 1 hit
PfamiView protein in Pfam
PF07966 A1_Propeptide, 1 hit
PF00026 Asp, 1 hit
PRINTSiPR00792 PEPSIN
SUPFAMiSSF50630 SSF50630, 1 hit
PROSITEiView protein in PROSITE
PS00141 ASP_PROTEASE, 2 hits
PS51767 PEPTIDASE_A1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO46498_BOVIN
AccessioniPrimary (citable) accession number: O46498
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: October 2, 2007
Last modified: March 28, 2018
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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