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Protein
Submitted name:

Uncharacterized protein

Gene

CELE_Y43F4B.5

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

ReactomeiR-CEL-3322077 Glycogen synthesis
R-CEL-6798695 Neutrophil degranulation
R-CEL-70171 Glycolysis
R-CEL-70221 Glycogen breakdown (glycogenolysis)
R-CEL-70370 Galactose catabolism
R-CEL-71336 Pentose phosphate pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
ORF Names:CELE_Y43F4B.5Imported, Y43F4B.5Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiY43F4B.5a ; CE16630 ; WBGene00012803

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

EPDiO45934
PaxDbiO45934
PeptideAtlasiO45934

2D gel databases

World-2DPAGEi0020:O45934

Expressioni

Gene expression databases

BgeeiWBGene00012803 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Interactioni

Protein-protein interaction databases

DIPiDIP-24402N
IntActiO45934, 1 interactor
STRINGi6239.Y43F4B.5a.1

Structurei

3D structure databases

ProteinModelPortaliO45934
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini48 – 185PGM_PMM_IInterPro annotationAdd BLAST138
Domaini221 – 320PGM_PMM_IIInterPro annotationAdd BLAST100
Domaini331 – 457PGM_PMM_IIIInterPro annotationAdd BLAST127
Domaini522 – 553PGM_PMM_IVInterPro annotationAdd BLAST32

Sequence similaritiesi

Belongs to the phosphohexose mutase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1220 Eukaryota
COG1109 LUCA
GeneTreeiENSGT00390000017247
HOGENOMiHOG000268676
InParanoidiO45934
KOiK15779
OMAiHWKVFTG
OrthoDBiEOG091G040C
PhylomeDBiO45934

Family and domain databases

InterProiView protein in InterPro
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005843 A-D-PHexomutase_C
IPR036900 A-D-PHexomutase_C_sf
IPR016066 A-D-PHexomutase_CS
IPR005841 Alpha-D-phosphohexomutase_SF
PfamiView protein in Pfam
PF02878 PGM_PMM_I, 1 hit
PF02879 PGM_PMM_II, 1 hit
PF02880 PGM_PMM_III, 1 hit
PF00408 PGM_PMM_IV, 1 hit
PRINTSiPR00509 PGMPMM
SUPFAMiSSF53738 SSF53738, 3 hits
SSF55957 SSF55957, 1 hit
PROSITEiView protein in PROSITE
PS00710 PGM_PMM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O45934-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTLGCAKLDK QVADWLAWDK NDKNRNEIQK LVDEKNVDAL KARMDTRLVF
60 70 80 90 100
GTAGVRSPMQ AGFGRLNDLT IIQITHGFAR HMLNVYGQPK NGVAIGFDGR
110 120 130 140 150
YNSRRFAELS ANVFVRNNIP VYLFSEVSPT PVVSWATIKL GCDAGLIITA
160 170 180 190 200
SHNPKEDNGY KAYWSNGAQI IGPHDTEIVR IKEAEPQPRD EYWDLSELKS
210 220 230 240 250
SPLFHSADVV IDPYFEVEKS LNFTREINGS TPLKFTYSAF HGIGYHYTKR
260 270 280 290 300
MFAEFGFPAS SFISVAEQQD PNPDFPTIPF PNPEEGRKVL TLAMETADKN
310 320 330 340 350
GSTVILANDP DADRIQMAEK QKDGEWRVFT GNEMGALITW WIWTNWRKAN
360 370 380 390 400
PNADASKVYI LNSAVSSQIV KTIADAEGFK NETTLTGFKW MGNRAEELRA
410 420 430 440 450
DGNQVILAWE ESIGYMPGHT MDKDGVSAAA VFAEIAAFLH AEGKSLQDQL
460 470 480 490 500
YALYNRYGFH LVRSTYWMVP APEVTKKLFS TLRADLKFPT KIGEAEVASV
510 520 530 540 550
RDLTIGYDNS KPDNKPVLPL STSSEMVTFF LKTGSVTTLR ASGTEPKIKY
560 570 580 590
YIELITAPGK TQNDLESVIS EMDQLEKDVV ATLLRPQQFG LIPRK
Length:595
Mass (Da):66,587
Last modified:June 1, 1998 - v1
Checksum:i4E0135585AAB0088
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q86DA0Q86DA0_CAEEL
Uncharacterized protein
CELE_Y43F4B.5, Y43F4B.5
459Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CAA16334.1
PIRiT26843
RefSeqiNP_001022872.1, NM_001027701.2
UniGeneiCel.32900

Genome annotation databases

EnsemblMetazoaiY43F4B.5a; Y43F4B.5a; WBGene00012803
GeneIDi176749
KEGGicel:CELE_Y43F4B.5
UCSCiY43F4B.5a.1 c. elegans

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284603 Genomic DNA Translation: CAA16334.1
PIRiT26843
RefSeqiNP_001022872.1, NM_001027701.2
UniGeneiCel.32900

3D structure databases

ProteinModelPortaliO45934
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-24402N
IntActiO45934, 1 interactor
STRINGi6239.Y43F4B.5a.1

2D gel databases

World-2DPAGEi0020:O45934

Proteomic databases

EPDiO45934
PaxDbiO45934
PeptideAtlasiO45934

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiY43F4B.5a; Y43F4B.5a; WBGene00012803
GeneIDi176749
KEGGicel:CELE_Y43F4B.5
UCSCiY43F4B.5a.1 c. elegans

Organism-specific databases

CTDi176749
WormBaseiY43F4B.5a ; CE16630 ; WBGene00012803

Phylogenomic databases

eggNOGiKOG1220 Eukaryota
COG1109 LUCA
GeneTreeiENSGT00390000017247
HOGENOMiHOG000268676
InParanoidiO45934
KOiK15779
OMAiHWKVFTG
OrthoDBiEOG091G040C
PhylomeDBiO45934

Enzyme and pathway databases

ReactomeiR-CEL-3322077 Glycogen synthesis
R-CEL-6798695 Neutrophil degranulation
R-CEL-70171 Glycolysis
R-CEL-70221 Glycogen breakdown (glycogenolysis)
R-CEL-70370 Galactose catabolism
R-CEL-71336 Pentose phosphate pathway

Gene expression databases

BgeeiWBGene00012803 Expressed in 5 organ(s), highest expression level in multi-cellular organism

Family and domain databases

InterProiView protein in InterPro
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005843 A-D-PHexomutase_C
IPR036900 A-D-PHexomutase_C_sf
IPR016066 A-D-PHexomutase_CS
IPR005841 Alpha-D-phosphohexomutase_SF
PfamiView protein in Pfam
PF02878 PGM_PMM_I, 1 hit
PF02879 PGM_PMM_II, 1 hit
PF02880 PGM_PMM_III, 1 hit
PF00408 PGM_PMM_IV, 1 hit
PRINTSiPR00509 PGMPMM
SUPFAMiSSF53738 SSF53738, 3 hits
SSF55957 SSF55957, 1 hit
PROSITEiView protein in PROSITE
PS00710 PGM_PMM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO45934_CAEEL
AccessioniPrimary (citable) accession number: O45934
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: October 10, 2018
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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