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Protein

Echinoderm microtubule-associated protein-like elp-1

Gene

elp-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.By similarity

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiO45487

Names & Taxonomyi

Protein namesi
Recommended name:
Echinoderm microtubule-associated protein-like elp-1
Gene namesi
Name:elp-1
ORF Names:F38A6.2
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiF38A6.2a ; CE15999 ; WBGene00001248 ; elp-1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000509661 – 891Echinoderm microtubule-associated protein-like elp-1Add BLAST891

Proteomic databases

PaxDbiO45487
PRIDEiO45487

Expressioni

Gene expression databases

BgeeiWBGene00001248
ExpressionAtlasiO45487 baseline and differential

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi6239.F38A6.2a

Structurei

3D structure databases

ProteinModelPortaliO45487
SMRiO45487
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati330 – 401WD 1Add BLAST72
Repeati404 – 447WD 2Add BLAST44
Repeati499 – 537WD 3Add BLAST39
Repeati541 – 579WD 4Add BLAST39
Repeati626 – 664WD 5Add BLAST39
Repeati708 – 747WD 6Add BLAST40
Repeati753 – 792WD 7Add BLAST40
Repeati816 – 853WD 8Add BLAST38
Repeati859 – 890WD 9Add BLAST32

Sequence similaritiesi

Belongs to the WD repeat EMAP family.Curated

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

eggNOGiKOG2106 Eukaryota
ENOG410XNTQ LUCA
GeneTreeiENSGT00550000074369
HOGENOMiHOG000017827
InParanoidiO45487
KOiK18595
OMAiWATSTCT
OrthoDBiEOG091G02HZ
PhylomeDBiO45487

Family and domain databases

Gene3Di2.130.10.10, 4 hits
InterProiView protein in InterPro
IPR005108 HELP
IPR011047 Quinoprotein_ADH-like_supfam
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
PfamiView protein in Pfam
PF03451 HELP, 1 hit
PF00400 WD40, 1 hit
SMARTiView protein in SMART
SM00320 WD40, 9 hits
SUPFAMiSSF50998 SSF50998, 4 hits
PROSITEiView protein in PROSITE
PS50082 WD_REPEATS_2, 1 hit
PS50294 WD_REPEATS_REGION, 2 hits

Sequencei

Sequence statusi: Complete.

O45487-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSISNGWSSS SIISDVLPEE EFEEVEEDEL ILNENDRLKF RVDELEKIVV
60 70 80 90 100
AQRNEILLLQ SSTVEILRRL QNLEIQDQSR SPTCSGYSSL PRRISGSKSS
110 120 130 140 150
YTMSPSHAPP RSSHANSKSL YINGMNNNSE EVSPGPPRHR PPTRGSDGMV
160 170 180 190 200
NVSVGKSARG SPMRKWVSTH DMKDTDRFRR LSTSSEASTS ATMNPIVNSV
210 220 230 240 250
RRLSTTHRQS SPSLLSLCSV ISRSPSTSSI LRKNNRTCQF SNGSGHLPIF
260 270 280 290 300
IGGKTVQVPV PTGYENMDPT MDQDPPTMKV TLKHVYSYRG KDVRSNIEML
310 320 330 340 350
PTGELVFFSA NLVVLMNITG EDRSQRIYHG HTCDVKCITL HPNKILVASG
360 370 380 390 400
QSSCHSVEKF QKPEHTSPID SPEDLVRQLE MEHTEAHVRI WDTIKLTTLM
410 420 430 440 450
VLNGFEKGIC HVAFSKTDSG SLLAVVDDSL KHLMSVWNWQ KGKREGEVKA
460 470 480 490 500
SNDVVFECKW HPTIRNLIVL YGKGHFSFFN YDPATGVLVK TVATFEGRDK
510 520 530 540 550
PKTVLSMCFG ENDQVVTGDS NGTISIWDPR TCKTTKQAHS VHPGGVYSLT
560 570 580 590 600
LAKSGKILSG GKDRMVSEWD LQDLVRTRRP IELPDEKGFP RVILQNGSEL
610 620 630 640 650
IIGTSSNTLL FGNIENSTNL TSLIEGDPGN LTFLLTCSSN QLITSSQCGT
660 670 680 690 700
LRIWNHIDKK VEFSKKFIDS VECVDVDVTN THIILGFAAG LWIVMNITKQ
710 720 730 740 750
QTIQEKKEGT APITAVKFAP SGATFAVATK DPHLTIYRID ASKNLLVIAR
760 770 780 790 800
IHHIPAPIVA LDFSSDSQYL RGQSIGAHLL FWTKAGEICD GTSVKDVKWG
810 820 830 840 850
SSRVKIGFET ALVAHSSNGQ VTAVAQCEDI SACGMENGTI RIYKNPVTSV
860 870 880 890
TAGFVELLGH GRIIKSVAFS NKIQLFSCSP TDNSVFEWCL E
Length:891
Mass (Da):98,372
Last modified:June 1, 1998 - v1
Checksum:iA8EFC84FA6FCE852
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z92833 Genomic DNA Translation: CAB07379.1
PIRiT21942
RefSeqiNP_001256950.1, NM_001270021.1
UniGeneiCel.4267

Genome annotation databases

EnsemblMetazoaiF38A6.2a.1; F38A6.2a.1; WBGene00001248
F38A6.2a.2; F38A6.2a.2; WBGene00001248
GeneIDi180358
KEGGicel:CELE_F38A6.2
UCSCiF38A6.2 c. elegans

Similar proteinsi

Entry informationi

Entry nameiEMAL_CAEEL
AccessioniPrimary (citable) accession number: O45487
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 18, 2001
Last sequence update: June 1, 1998
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

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