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Protein
Submitted name:

CYtochrome P450 family

Gene

cyp-33c2

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-CEL-156581 Methylation
R-CEL-193048 Androgen biosynthesis
R-CEL-193993 Mineralocorticoid biosynthesis
R-CEL-194002 Glucocorticoid biosynthesis
R-CEL-211957 Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
R-CEL-211976 Endogenous sterols
R-CEL-211981 Xenobiotics
R-CEL-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
R-CEL-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
R-CEL-5423646 Aflatoxin activation and detoxification
R-CEL-9018681 Biosynthesis of protectins
R-CEL-9027307 Biosynthesis of maresin-like SPMs

Names & Taxonomyi

Protein namesi
Submitted name:
CYtochrome P450 familyImported
Gene namesi
Name:cyp-33c2Imported
Synonyms:cyp-33C2Imported
ORF Names:C45H4.17Imported, CELE_C45H4.17Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC45H4.17a ; CE25818 ; WBGene00016697 ; cyp-33C2

PTM / Processingi

Proteomic databases

PaxDbiO44706
PeptideAtlasiO44706

Expressioni

Gene expression databases

BgeeiWBGene00016697 Expressed in 3 organ(s), highest expression level in adult organism

Interactioni

Protein-protein interaction databases

DIPiDIP-26774N
STRINGi6239.C45H4.17

Structurei

3D structure databases

ProteinModelPortaliO44706
SMRiO44706
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140831
HOGENOMiHOG000036993
InParanoidiO44706
KOiK17955
OMAiIDMRPVF
OrthoDBiEOG091G0BT8
PhylomeDBiO44706

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

O44706-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLIILLLTVL TVYLVYELYW KRRNFPPGPC PLPVFGNLLS IANPPPGYEA
60 70 80 90 100
FERWTKKYGD IYTFWIGNTP HIMINTWDKI KETYIRDAET YTNKVRLPAL
110 120 130 140 150
DLFRGGEYGI IDSNGATWRE HRRFALSTMR DFGLGKNLMQ ENILMEVQDV
160 170 180 190 200
FARLDAKLGS ETDIPEVFDH AVANVVNQLL FGYRFVGPKE SEYQELKRII
210 220 230 240 250
EAPTDLFGKP HMFLAMNIPV IAKLMPEFMY EGPFKDFRDT AFAFFNKQIE
260 270 280 290 300
AHRQEVDLND LNSESTDFVE TFLKEQKRRE SEGDSETFSN VQLSNVCMDL
310 320 330 340 350
WFAGLNTTTN TITWAISYIL HHPEVQDKVH EEMDKVIGSD RLITTADKND
360 370 380 390 400
LPYFNAFINE AQRGINIVPL NLQHATTRDT VINGFKIPKG TGVVAQISTV
410 420 430 440 450
MNNEEVFPDP HTFNPDRFID EHGKLKRVEE LAPFSVGKRS CPGEGLARME
460 470 480 490
LFLFIANFLN RYKIYPSKEG PPSMDKSNGA LIAPRLFSAT LKRRS
Length:495
Mass (Da):56,822
Last modified:October 1, 2001 - v2
Checksum:iAE427F4F3F29B74C
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0M7RF95A0A0M7RF95_CAEEL
CYtochrome P450 family
cyp-33c2 cyp-33C2, C45H4.17, CELE_C45H4.17
95Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD67427.1
PIRiT32730
RefSeqiNP_503594.1, NM_071193.1
UniGeneiCel.4490

Genome annotation databases

EnsemblMetazoaiC45H4.17a; C45H4.17a; WBGene00016697
GeneIDi178695
KEGGicel:CELE_C45H4.17
UCSCiC45H4.17 c. elegans

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD67427.1
PIRiT32730
RefSeqiNP_503594.1, NM_071193.1
UniGeneiCel.4490

3D structure databases

ProteinModelPortaliO44706
SMRiO44706
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-26774N
STRINGi6239.C45H4.17

Proteomic databases

PaxDbiO44706
PeptideAtlasiO44706

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiC45H4.17a; C45H4.17a; WBGene00016697
GeneIDi178695
KEGGicel:CELE_C45H4.17
UCSCiC45H4.17 c. elegans

Organism-specific databases

CTDi178695
WormBaseiC45H4.17a ; CE25818 ; WBGene00016697 ; cyp-33C2

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00900000140831
HOGENOMiHOG000036993
InParanoidiO44706
KOiK17955
OMAiIDMRPVF
OrthoDBiEOG091G0BT8
PhylomeDBiO44706

Enzyme and pathway databases

ReactomeiR-CEL-156581 Methylation
R-CEL-193048 Androgen biosynthesis
R-CEL-193993 Mineralocorticoid biosynthesis
R-CEL-194002 Glucocorticoid biosynthesis
R-CEL-211957 Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2
R-CEL-211976 Endogenous sterols
R-CEL-211981 Xenobiotics
R-CEL-2142670 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)
R-CEL-2142816 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)
R-CEL-5423646 Aflatoxin activation and detoxification
R-CEL-9018681 Biosynthesis of protectins
R-CEL-9027307 Biosynthesis of maresin-like SPMs

Gene expression databases

BgeeiWBGene00016697 Expressed in 3 organ(s), highest expression level in adult organism

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO44706_CAEEL
AccessioniPrimary (citable) accession number: O44706
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: October 1, 2001
Last modified: October 10, 2018
This is version 145 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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