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Protein

Tumor protein D54

Gene

TPD52L2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • regulation of cell proliferation Source: UniProtKB

Enzyme and pathway databases

SignaLink: a signaling pathway resource with multi-layered regulatory networks

More...
SignaLinki
O43399

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tumor protein D54
Short name:
hD54
Alternative name(s):
Tumor protein D52-like 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TPD52L2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 20

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000101150.17

Human Gene Nomenclature Database

More...
HGNCi
HGNC:12007 TPD52L2

Online Mendelian Inheritance in Man (OMIM)

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MIMi
603747 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O43399

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7165

Open Targets

More...
OpenTargetsi
ENSG00000101150

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36688

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TPD52L2

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001857441 – 206Tumor protein D54Add BLAST206

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineCombined sources1
Modified residuei3PhosphoserineCombined sources1
Modified residuei12PhosphoserineCombined sources1
Modified residuei19PhosphoserineCombined sources1
Modified residuei21PhosphoserineCombined sources1
Modified residuei96PhosphoserineCombined sources1
Modified residuei149PhosphoserineCombined sources1
Modified residuei161PhosphoserineCombined sources1
Modified residuei163PhosphothreonineCombined sources1
Modified residuei166PhosphoserineCombined sources1
Modified residuei173PhosphothreonineCombined sources1
Modified residuei192PhosphoserineBy similarity1
Modified residuei195PhosphoserineCombined sources1

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
O43399

PeptideAtlas

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PeptideAtlasi
O43399

PRoteomics IDEntifications database

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PRIDEi
O43399

ProteomicsDB human proteome resource

More...
ProteomicsDBi
48923
48924 [O43399-2]
48925 [O43399-3]
48926 [O43399-4]
48927 [O43399-5]

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
O43399-5 [O43399-5]

2D gel databases

USC-OGP 2-DE database

More...
OGPi
O43399

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O43399

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O43399

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O43399

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000101150 Expressed in 230 organ(s), highest expression level in blood

CleanEx database of gene expression profiles

More...
CleanExi
HS_TPD52L2

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
O43399 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O43399 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA047489

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a homodimer or heterodimer with other members of the family (By similarity). Interacts with MAL2.By similarity1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
Tpd52Q623932EBI-782616,EBI-782591From Mus musculus.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
113018, 71 interactors

Protein interaction database and analysis system

More...
IntActi
O43399, 12 interactors

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O43399

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili38 – 82Sequence analysisAdd BLAST45

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TPD52 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

Ensembl GeneTree

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GeneTreei
ENSGT00940000155572

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231968

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG058643

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
O43399

Identification of Orthologs from Complete Genome Data

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OMAi
RARPFSH

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0MLN

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O43399

TreeFam database of animal gene trees

More...
TreeFami
TF317562

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.50.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012341 6hp_glycosidase-like_sf
IPR007327 TPD52

The PANTHER Classification System

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PANTHERi
PTHR19307 PTHR19307, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF04201 TPD52, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (7+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 7 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Note: Additional isoforms seem to exist.

This entry has 7 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: O43399-1) [UniParc]FASTAAdd to basket
Also known as: HD54+ins2

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDSAGQDINL NSPNKGLLSD SMTDVPVDTG VAARTPAVEG LTEAEEEELR
60 70 80 90 100
AELTKVEEEI VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV
110 120 130 140 150
QVSSAYVKTS EKLGEWNEKV TQSDLYKKTQ ETLSQAGQKT SAALSTVGSA
160 170 180 190 200
ISRKLGDMRN SATFKSFEDR VGTIKSKVVG DRENGSDNLP SSAGSGDKPL

SDPAPF
Length:206
Mass (Da):22,238
Last modified:January 23, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i58F01BC67B1E3DE9
GO
Isoform 2 (identifier: O43399-2) [UniParc]FASTAAdd to basket
Also known as: HD54-ins2

The sequence of this isoform differs from the canonical sequence as follows:
     106-125: Missing.

Show »
Length:186
Mass (Da):19,901
Checksum:i002CD68479D8250C
GO
Isoform 3 (identifier: O43399-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     106-125: Missing.
     159-159: R → RAHPFSHSFSSYSIRHSISMPAMR

Show »
Length:209
Mass (Da):22,517
Checksum:i5087B635B9155443
GO
Isoform 4 (identifier: O43399-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     106-125: Missing.
     157-157: D → DMSSYSIRHSISMPA

Show »
Length:200
Mass (Da):21,450
Checksum:i9BAD0A523C8F14DB
GO
Isoform 5 (identifier: O43399-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     157-157: D → DMSSYSIRHSISMPA

Note: No experimental confirmation available.
Show »
Length:220
Mass (Da):23,787
Checksum:i0A47C22C7C285FFF
GO
Isoform 6 (identifier: O43399-6) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     7-29: Missing.
     106-125: Missing.

Show »
Length:163
Mass (Da):17,473
Checksum:i1CF34D45DF97AABC
GO
Isoform 7 (identifier: O43399-7) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     157-157: D → DMRAHPFSHSFSSYSIRHSISMPA

Note: No experimental confirmation available.
Show »
Length:229
Mass (Da):24,854
Checksum:i0AF18A6C7059BE30
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WYR3A0A087WYR3_HUMAN
Tumor protein D54
TPD52L2
222Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WZ51A0A087WZ51_HUMAN
Tumor protein D54
TPD52L2
152Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BU165202 differs from that shown. Reason: Frameshift at positions 155, 157, 173 and 188.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti72R → K in AAC98478 (PubMed:9838088).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0451547 – 29Missing in isoform 6. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_006547106 – 125Missing in isoform 2, isoform 3, isoform 4 and isoform 6. 1 PublicationAdd BLAST20
Alternative sequenceiVSP_038361157D → DMSSYSIRHSISMPA in isoform 4 and isoform 5. 2 Publications1
Alternative sequenceiVSP_047409157D → DMRAHPFSHSFSSYSIRHSI SMPA in isoform 7. 1 Publication1
Alternative sequenceiVSP_036756159R → RAHPFSHSFSSYSIRHSISM PAMR in isoform 3. Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF004429 mRNA Translation: AAC98477.1
AF004430 mRNA Translation: AAC98478.1
AK055068 mRNA Translation: BAG51460.1
AK298366 mRNA Translation: BAG60608.1
BT019631 mRNA Translation: AAV38437.1
AL118506 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75195.1
CH471077 Genomic DNA Translation: EAW75197.1
CH471077 Genomic DNA Translation: EAW75198.1
CH471077 Genomic DNA Translation: EAW75199.1
CH471077 Genomic DNA Translation: EAW75201.1
BC006804 mRNA Translation: AAH06804.1
BU165202 mRNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS13540.1 [O43399-1]
CCDS13541.1 [O43399-2]
CCDS13542.1 [O43399-7]
CCDS13543.1 [O43399-3]
CCDS13544.1 [O43399-5]
CCDS13545.1 [O43399-4]
CCDS58785.1 [O43399-6]

NCBI Reference Sequences

More...
RefSeqi
NP_001230821.1, NM_001243892.1 [O43399-6]
NP_003279.2, NM_003288.3 [O43399-1]
NP_955392.1, NM_199360.2 [O43399-7]
NP_955393.1, NM_199361.2 [O43399-3]
NP_955394.1, NM_199362.2 [O43399-5]
NP_955395.1, NM_199363.2 [O43399-4]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.473296

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000217121; ENSP00000217121; ENSG00000101150 [O43399-7]
ENST00000346249; ENSP00000343547; ENSG00000101150 [O43399-1]
ENST00000348257; ENSP00000343554; ENSG00000101150 [O43399-2]
ENST00000351424; ENSP00000340006; ENSG00000101150 [O43399-3]
ENST00000352482; ENSP00000344647; ENSG00000101150 [O43399-5]
ENST00000358548; ENSP00000351350; ENSG00000101150 [O43399-4]
ENST00000369927; ENSP00000358943; ENSG00000101150 [O43399-6]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7165

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7165

UCSC genome browser

More...
UCSCi
uc002ygy.4 human [O43399-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004429 mRNA Translation: AAC98477.1
AF004430 mRNA Translation: AAC98478.1
AK055068 mRNA Translation: BAG51460.1
AK298366 mRNA Translation: BAG60608.1
BT019631 mRNA Translation: AAV38437.1
AL118506 Genomic DNA No translation available.
CH471077 Genomic DNA Translation: EAW75195.1
CH471077 Genomic DNA Translation: EAW75197.1
CH471077 Genomic DNA Translation: EAW75198.1
CH471077 Genomic DNA Translation: EAW75199.1
CH471077 Genomic DNA Translation: EAW75201.1
BC006804 mRNA Translation: AAH06804.1
BU165202 mRNA No translation available.
CCDSiCCDS13540.1 [O43399-1]
CCDS13541.1 [O43399-2]
CCDS13542.1 [O43399-7]
CCDS13543.1 [O43399-3]
CCDS13544.1 [O43399-5]
CCDS13545.1 [O43399-4]
CCDS58785.1 [O43399-6]
RefSeqiNP_001230821.1, NM_001243892.1 [O43399-6]
NP_003279.2, NM_003288.3 [O43399-1]
NP_955392.1, NM_199360.2 [O43399-7]
NP_955393.1, NM_199361.2 [O43399-3]
NP_955394.1, NM_199362.2 [O43399-5]
NP_955395.1, NM_199363.2 [O43399-4]
UniGeneiHs.473296

3D structure databases

ProteinModelPortaliO43399
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi113018, 71 interactors
IntActiO43399, 12 interactors

PTM databases

iPTMnetiO43399
PhosphoSitePlusiO43399
SwissPalmiO43399

Polymorphism and mutation databases

BioMutaiTPD52L2

2D gel databases

OGPiO43399

Proteomic databases

EPDiO43399
PeptideAtlasiO43399
PRIDEiO43399
ProteomicsDBi48923
48924 [O43399-2]
48925 [O43399-3]
48926 [O43399-4]
48927 [O43399-5]
TopDownProteomicsiO43399-5 [O43399-5]

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
7165
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000217121; ENSP00000217121; ENSG00000101150 [O43399-7]
ENST00000346249; ENSP00000343547; ENSG00000101150 [O43399-1]
ENST00000348257; ENSP00000343554; ENSG00000101150 [O43399-2]
ENST00000351424; ENSP00000340006; ENSG00000101150 [O43399-3]
ENST00000352482; ENSP00000344647; ENSG00000101150 [O43399-5]
ENST00000358548; ENSP00000351350; ENSG00000101150 [O43399-4]
ENST00000369927; ENSP00000358943; ENSG00000101150 [O43399-6]
GeneIDi7165
KEGGihsa:7165
UCSCiuc002ygy.4 human [O43399-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
7165
DisGeNETi7165
EuPathDBiHostDB:ENSG00000101150.17

GeneCards: human genes, protein and diseases

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GeneCardsi
TPD52L2
HGNCiHGNC:12007 TPD52L2
HPAiHPA047489
MIMi603747 gene
neXtProtiNX_O43399
OpenTargetsiENSG00000101150
PharmGKBiPA36688

GenAtlas: human gene database

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GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000155572
HOGENOMiHOG000231968
HOVERGENiHBG058643
InParanoidiO43399
OMAiRARPFSH
OrthoDBiEOG091G0MLN
PhylomeDBiO43399
TreeFamiTF317562

Enzyme and pathway databases

SignaLinkiO43399

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
TPD52L2 human

The Gene Wiki collection of pages on human genes and proteins

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GeneWikii
TPD52L2

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
7165

Protein Ontology

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PROi
PR:O43399

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSG00000101150 Expressed in 230 organ(s), highest expression level in blood
CleanExiHS_TPD52L2
ExpressionAtlasiO43399 baseline and differential
GenevisibleiO43399 HS

Family and domain databases

Gene3Di1.50.10.10, 1 hit
InterProiView protein in InterPro
IPR012341 6hp_glycosidase-like_sf
IPR007327 TPD52
PANTHERiPTHR19307 PTHR19307, 1 hit
PfamiView protein in Pfam
PF04201 TPD52, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTPD54_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O43399
Secondary accession number(s): B4DPJ6
, E1P5G7, O43398, Q5JWU5, Q5JWU6, Q5JWU8, Q5U0E0, Q9H3Z6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2001
Last sequence update: January 23, 2002
Last modified: December 5, 2018
This is version 170 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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