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Protein

Testis-expressed protein 33

Gene

TEX33

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed protein 33
Gene namesi
Name:TEX33
Synonyms:C22orf33, EAN57
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000185264.11
HGNCiHGNC:28568 TEX33
neXtProtiNX_O43247

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000185264
PharmGKBiPA162378965

Polymorphism and mutation databases

BioMutaiTEX33

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000869021 – 280Testis-expressed protein 33Add BLAST280

Proteomic databases

PaxDbiO43247
PeptideAtlasiO43247
PRIDEiO43247
ProteomicsDBi48824
48825 [O43247-2]

PTM databases

iPTMnetiO43247
PhosphoSitePlusiO43247

Expressioni

Gene expression databases

BgeeiENSG00000185264 Expressed in 34 organ(s), highest expression level in testis
CleanExiHS_C22orf33
ExpressionAtlasiO43247 baseline and differential
GenevisibleiO43247 HS

Organism-specific databases

HPAiHPA005998

Interactioni

Protein-protein interaction databases

BioGridi130916, 8 interactors
IntActiO43247, 10 interactors
STRINGi9606.ENSP00000371243

Structurei

3D structure databases

ProteinModelPortaliO43247
SMRiO43247
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IJF8 Eukaryota
ENOG410Y5BD LUCA
GeneTreeiENSGT00390000013198
HOGENOMiHOG000048730
HOVERGENiHBG061061
InParanoidiO43247
OMAiYYDLGYN
OrthoDBiEOG091G12U6
PhylomeDBiO43247
TreeFamiTF335904

Family and domain databases

InterProiView protein in InterPro
IPR029234 TEX33
PANTHERiPTHR31702 PTHR31702, 1 hit
PfamiView protein in Pfam
PF15400 TEX33, 1 hit

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All

Isoform 1 (identifier: O43247-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MELGHGAGTT TFTRAHLNDK EGQQDLDPWK AAYSSLDTSK FKNQGLSSPQ
60 70 80 90 100
PLPLGASAQG SSLGQCHLKE IPPPPPTAAS RDSLGMDPQS RSLKNAGSRS
110 120 130 140 150
SSRENRATSG EGAQPCQGTD DGPSLGAQDQ RSTPTNQKGS IIPNNIRHKF
160 170 180 190 200
GSNVVDQLVS EEQAQKAIDE VFEGQKRASS WPSRTQNPVE ISSVFSDYYD
210 220 230 240 250
LGYNMRSNLF RGAAEETKSL MKASYTPEVI EKSVRDLEHW HGRKTDDLGR
260 270 280
WHQKNAMNLN LQKALEEKYG ENSKSKSSKY
Length:280
Mass (Da):30,725
Last modified:July 5, 2005 - v2
Checksum:i45647FA2FE223123
GO
Isoform 2 (identifier: O43247-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-85: Missing.

Note: No experimental confirmation available.
Show »
Length:195
Mass (Da):21,844
Checksum:iE6DE4B8BCBEE0D1A
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H0Y6N4H0Y6N4_HUMAN
Testis-expressed protein 33
TEX33
139Annotation score:

Sequence cautioni

The sequence CAA72029 differs from that shown. Reason: Erroneous gene model prediction.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0283511 – 85Missing in isoform 2. 1 PublicationAdd BLAST85

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456416 mRNA Translation: CAG30302.1
Z73420 Genomic DNA No translation available.
Z82180 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW60128.1
BC042635 mRNA Translation: AAH42635.1
Y11142 Genomic DNA Translation: CAA72029.1 Sequence problems.
CCDSiCCDS13937.1 [O43247-2]
CCDS54524.1 [O43247-1]
RefSeqiNP_001157329.1, NM_001163857.1 [O43247-1]
NP_848647.1, NM_178552.3 [O43247-2]
XP_011528467.1, XM_011530165.2 [O43247-1]
XP_011528468.1, XM_011530166.1 [O43247-2]
UniGeneiHs.124502

Genome annotation databases

EnsembliENST00000381821; ENSP00000371243; ENSG00000185264 [O43247-1]
ENST00000402860; ENSP00000385179; ENSG00000185264 [O43247-2]
ENST00000405091; ENSP00000386118; ENSG00000185264 [O43247-1]
GeneIDi339669
KEGGihsa:339669
UCSCiuc003aqe.4 human [O43247-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR456416 mRNA Translation: CAG30302.1
Z73420 Genomic DNA No translation available.
Z82180 Genomic DNA No translation available.
CH471095 Genomic DNA Translation: EAW60128.1
BC042635 mRNA Translation: AAH42635.1
Y11142 Genomic DNA Translation: CAA72029.1 Sequence problems.
CCDSiCCDS13937.1 [O43247-2]
CCDS54524.1 [O43247-1]
RefSeqiNP_001157329.1, NM_001163857.1 [O43247-1]
NP_848647.1, NM_178552.3 [O43247-2]
XP_011528467.1, XM_011530165.2 [O43247-1]
XP_011528468.1, XM_011530166.1 [O43247-2]
UniGeneiHs.124502

3D structure databases

ProteinModelPortaliO43247
SMRiO43247
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi130916, 8 interactors
IntActiO43247, 10 interactors
STRINGi9606.ENSP00000371243

PTM databases

iPTMnetiO43247
PhosphoSitePlusiO43247

Polymorphism and mutation databases

BioMutaiTEX33

Proteomic databases

PaxDbiO43247
PeptideAtlasiO43247
PRIDEiO43247
ProteomicsDBi48824
48825 [O43247-2]

Protocols and materials databases

DNASUi339669
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000381821; ENSP00000371243; ENSG00000185264 [O43247-1]
ENST00000402860; ENSP00000385179; ENSG00000185264 [O43247-2]
ENST00000405091; ENSP00000386118; ENSG00000185264 [O43247-1]
GeneIDi339669
KEGGihsa:339669
UCSCiuc003aqe.4 human [O43247-1]

Organism-specific databases

CTDi339669
EuPathDBiHostDB:ENSG00000185264.11
GeneCardsiTEX33
HGNCiHGNC:28568 TEX33
HPAiHPA005998
neXtProtiNX_O43247
OpenTargetsiENSG00000185264
PharmGKBiPA162378965
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IJF8 Eukaryota
ENOG410Y5BD LUCA
GeneTreeiENSGT00390000013198
HOGENOMiHOG000048730
HOVERGENiHBG061061
InParanoidiO43247
OMAiYYDLGYN
OrthoDBiEOG091G12U6
PhylomeDBiO43247
TreeFamiTF335904

Miscellaneous databases

GenomeRNAii339669
PROiPR:O43247

Gene expression databases

BgeeiENSG00000185264 Expressed in 34 organ(s), highest expression level in testis
CleanExiHS_C22orf33
ExpressionAtlasiO43247 baseline and differential
GenevisibleiO43247 HS

Family and domain databases

InterProiView protein in InterPro
IPR029234 TEX33
PANTHERiPTHR31702 PTHR31702, 1 hit
PfamiView protein in Pfam
PF15400 TEX33, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTEX33_HUMAN
AccessioniPrimary (citable) accession number: O43247
Secondary accession number(s): B1AH46
, Q6ICF2, Q8IVQ2, Q9Y4V8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: July 5, 2005
Last modified: September 12, 2018
This is version 123 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 22
    Human chromosome 22: entries, gene names and cross-references to MIM
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