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UniProtKB - O43081 (YHS6_SCHPO)
Protein
Uncharacterized MFS-type transporter C947.06c
Gene
SPBC947.06c
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- spermidine transmembrane transporter activity Source: PomBase
- spermine transmembrane transporter activity Source: PomBase
- xenobiotic transmembrane transporter activity Source: GO_Central
GO - Biological processi
- spermidine transmembrane transport Source: PomBase
- spermine transmembrane transport Source: PomBase
- xenobiotic detoxification by transmembrane export across the plasma membrane Source: GO_Central
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized MFS-type transporter C947.06c |
Gene namesi | ORF Names:SPBC947.06c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC947.06c |
VEuPathDBi | FungiDB:SPBC947.06c |
Subcellular locationi
Other locations
- Membrane Sequence analysis; Multi-pass membrane protein Sequence analysis
Plasma Membrane
- plasma membrane Source: PomBase
Other locations
- integral component of membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 93 – 113 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 123 – 143 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 153 – 173 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 180 – 200 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 214 – 234 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 288 – 308 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 327 – 347 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 368 – 388 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 393 – 413 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 427 – 449 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 461 – 481 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000343519 | 1 – 498 | Uncharacterized MFS-type transporter C947.06cAdd BLAST | 498 |
Proteomic databases
PaxDbi | O43081 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 277789, 13 interactors |
STRINGi | 4896.SPBC947.06c.1 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the major facilitator superfamily.Sequence analysis
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0255, Eukaryota |
HOGENOMi | CLU_008455_11_6_1 |
InParanoidi | O43081 |
OMAi | GVHWGAS |
PhylomeDBi | O43081 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
O43081-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKENDHLNSV SSSEIEKCDE DVEEELYSYP DSDFLVTFNG EDDPEKPLNW
60 70 80 90 100
PVSIKLLNTA LYGLTTFAAQ FNSTTMSPTT SHLVNAYPIG HEVAVLPTCL
110 120 130 140 150
YILGIAFGPM IFAPFSEVNG RKIGVLVPFF LSILFTIGTA SSDSVAAIMC
160 170 180 190 200
TRFFAGLFAG APVVSSGGVM ADLWCPAQRG TALIFYAFFV VSGADFGPII
210 220 230 240 250
SSLVTEHSDT AWRWPLWTIV IIECFILTLD VFLIKETFGP VILATKAKNL
260 270 280 290 300
RLTTKNWGLH AAHDEYRLDF KEFVTLHLVR PFAMLATPIV FFIAMFASYV
310 320 330 340 350
YGILYLVLTT IPYTFGMTKN WQGTISTLPM IAMFTGVVIG GSFNIMWNQR
360 370 380 390 400
YAKLITANGG KPLPEQRLPL MMAVGWLMPA GIFVFAWTNS PNIHWIAPFI
410 420 430 440 450
GISMMGAGFF VIFQGCLNYL VDTFTKFAAS AIAANTFTRS IFAGTFPLFS
460 470 480 490
EIMFKKLGVH WGGSLVGFIA LGMIPIPFIF YMMGDKLRRK NRFIKLIT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA17034.1 |
PIRi | T40776 |
RefSeqi | NP_595270.1, NM_001021177.2 |
Genome annotation databases
EnsemblFungii | SPBC947.06c.1; SPBC947.06c.1:pep; SPBC947.06c |
GeneIDi | 2541275 |
KEGGi | spo:SPBC947.06c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA17034.1 |
PIRi | T40776 |
RefSeqi | NP_595270.1, NM_001021177.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 277789, 13 interactors |
STRINGi | 4896.SPBC947.06c.1 |
Proteomic databases
PaxDbi | O43081 |
Genome annotation databases
EnsemblFungii | SPBC947.06c.1; SPBC947.06c.1:pep; SPBC947.06c |
GeneIDi | 2541275 |
KEGGi | spo:SPBC947.06c |
Organism-specific databases
PomBasei | SPBC947.06c |
VEuPathDBi | FungiDB:SPBC947.06c |
Phylogenomic databases
eggNOGi | KOG0255, Eukaryota |
HOGENOMi | CLU_008455_11_6_1 |
InParanoidi | O43081 |
OMAi | GVHWGAS |
PhylomeDBi | O43081 |
Miscellaneous databases
PROi | PR:O43081 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YHS6_SCHPO | |
Accessioni | O43081Primary (citable) accession number: O43081 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 2008 |
Last sequence update: | June 1, 1998 | |
Last modified: | September 29, 2021 | |
This is version 122 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families