Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 108 (02 Jun 2021)
Sequence version 1 (01 Jun 1998)
Previous versions | rss
Add a publicationFeedback
Protein

Protein NRDE2 homolog

Gene

SPBC20F10.05

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein NRDE2 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SPBC20F10.05
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPBC20F10.05

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPBC20F10.05

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003431441 – 972Protein NRDE2 homologAdd BLAST972

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei970Phosphoserine1 Publication1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O42975

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O42975

PRoteomics IDEntifications database

More...
PRIDEi
O42975

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O42975

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O42975

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
277216, 57 interactors

Protein interaction database and analysis system

More...
IntActi
O42975, 10 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPBC20F10.05.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O42975

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati159 – 191HAT 1Add BLAST33
Repeati250 – 282HAT 2Add BLAST33
Repeati318 – 350HAT 3Add BLAST33
Repeati355 – 386HAT 4Add BLAST32
Repeati608 – 640HAT 5Add BLAST33
Repeati788 – 820HAT 6Add BLAST33
Repeati860 – 894HAT 7Add BLAST35

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 61DisorderedSequence analysisAdd BLAST61

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 23Polar residuesSequence analysisAdd BLAST23
Compositional biasi39 – 61Polar residuesSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NRDE2 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1972, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_312419_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O42975

Identification of Orthologs from Complete Genome Data

More...
OMAi
CKEREST

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O42975

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013633, NRDE-2

The PANTHER Classification System

More...
PANTHERi
PTHR13471, PTHR13471, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08424, NRDE-2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O42975-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSNHNTSVP KFSSFNSVKA KKNPITKSNK KYRSSHDQVS SNHAKSSFPS
60 70 80 90 100
HRSIQSNFAV DTKGEKQNLL YGINKRPVPK YHRSSSSVYG SAPLLRIVKE
110 120 130 140 150
SKEGITLNKK KSLEIKYDEE RSFDEKENDE SEFEDGQQGF IPLLVNRNSD
160 170 180 190 200
PSEKSTFSLN ILKAIKETDE EIKKNPGKAR LWIKMCEYQE RLLFDEFRRS
210 220 230 240 250
NSDDIKGKLK IENNSRSVKL SILEKALKEV KGCDHEILVS YYLQLGSEEW
260 270 280 290 300
SKEETNQKFE EVLIEHPGYL NLWMKYAEYF TGISEFTFND CLNMFSKCFK
310 320 330 340 350
FLKQKLSDRK SCKERESTDV TSNFEVEEAI LHLLIRLCDF LKNCGYYELA
360 370 380 390 400
WSIFQANMEL CYFYPRYLEK KLDSTFFESF SKFWNSDTPK FSEENARGWC
410 420 430 440 450
NVLDDESSQQ NQNFSSEIGI FQTVKLWYLN ESKFDTNPPP RSTMSCRKLS
460 470 480 490 500
GIDDPFRYIV FNDIQDFIVC FESETIAFAF KYKFFAFCGV PLFPPGISTN
510 520 530 540 550
SWFASYDKGI YNLLFGMASS ESFINGQIAE KNSFQFPCSI LPSYIDLFIS
560 570 580 590 600
LMSFKNLNFK LFDYNLAHHV KESMERAFHQ LVFSADDEYL ASVYLIYLKQ
610 620 630 640 650
METKNLSEEK PQVNKIVKKI LKKYDSSVSV WNTYAQLEHL SGAFTMAETI
660 670 680 690 700
FKTIFQIHAS QLRYIDNLNV YKNWAFRKLL INDTEGCLVI IKCLLFPGDK
710 720 730 740 750
SLTSDNNRAS EMLFGMLENC ASKEELLYVC LIYTIWTHCT DMDSMDNCVY
760 770 780 790 800
LCIQKFESYG WGASSEMECY FSYCSLIFYY QATTLQFYNL PKVRPFFEKG
810 820 830 840 850
VTLFSANTAI WEVYIFFESK LRQENKPKIR AMKILKSASN AVVTACWYLF
860 870 880 890 900
YVAVQQIEPT NSQYFLRTLD ITLNNEKLKS VAKFWRIYLK ILNLRLNGTE
910 920 930 940 950
WVSAITTKAL ASCPCNKGVC MDVIDLLLKK EMESRAIICY IIMLEKGFRV
960 970
HNEIRRDVLK FERGDELILS PN
Length:972
Mass (Da):113,249
Last modified:June 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i39EA1551A2C5DD8F
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA16845.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T39876

NCBI Reference Sequences

More...
RefSeqi
NP_596369.1, NM_001022290.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPBC20F10.05.1; SPBC20F10.05.1:pep; SPBC20F10.05

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2540691

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPBC20F10.05

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA16845.1
PIRiT39876
RefSeqiNP_596369.1, NM_001022290.2

3D structure databases

SMRiO42975
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi277216, 57 interactors
IntActiO42975, 10 interactors
STRINGi4896.SPBC20F10.05.1

PTM databases

iPTMnetiO42975
SwissPalmiO42975

Proteomic databases

MaxQBiO42975
PaxDbiO42975
PRIDEiO42975

Genome annotation databases

EnsemblFungiiSPBC20F10.05.1; SPBC20F10.05.1:pep; SPBC20F10.05
GeneIDi2540691
KEGGispo:SPBC20F10.05

Organism-specific databases

PomBaseiSPBC20F10.05
VEuPathDBiFungiDB:SPBC20F10.05

Phylogenomic databases

eggNOGiKOG1972, Eukaryota
HOGENOMiCLU_312419_0_0_1
InParanoidiO42975
OMAiCKEREST
PhylomeDBiO42975

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O42975

Family and domain databases

InterProiView protein in InterPro
IPR013633, NRDE-2
PANTHERiPTHR13471, PTHR13471, 1 hit
PfamiView protein in Pfam
PF08424, NRDE-2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNRDE2_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O42975
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 2008
Last sequence update: June 1, 1998
Last modified: June 2, 2021
This is version 108 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again