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UniProtKB - O42944 (OMH2_SCHPO)
Protein
O-glycoside alpha-1,2-mannosyltransferase homolog 2
Gene
omh2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Probable mannosyltransferase involved in O-glycosylation of cell wall and secreted proteins.
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 271 | NucleophileSequence analysis | 1 |
GO - Molecular functioni
- alpha-1,2-mannosyltransferase activity Source: PomBase
GO - Biological processi
- cell wall mannoprotein biosynthetic process Source: PomBase
- mannosylation Source: GO_Central
- protein N-linked glycosylation Source: GO_Central
- protein O-linked glycosylation Source: GO_Central
- protein O-linked mannosylation Source: PomBase
Keywordsi
Molecular function | Glycosyltransferase, Transferase |
Protein family/group databases
CAZyi | GT15, Glycosyltransferase Family 15 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:omh2 ORF Names:SPBC16H5.09c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC16H5.09c, omh2 |
VEuPathDBi | FungiDB:SPBC16H5.09c |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Single-pass type II membrane protein 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: PomBase
- endoplasmic reticulum membrane Source: UniProtKB-SubCell
Golgi apparatus
- Golgi apparatus Source: GO_Central
- Golgi membrane Source: PomBase
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 6 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 7 – 27 | Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST | 21 | |
Topological domaini | 28 – 372 | LumenalSequence analysisAdd BLAST | 345 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000316584 | 1 – 372 | O-glycoside alpha-1,2-mannosyltransferase homolog 2Add BLAST | 372 |
Proteomic databases
MaxQBi | O42944 |
PaxDbi | O42944 |
PTM databases
SwissPalmi | O42944 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 276450, 3 interactors |
STRINGi | 4896.SPBC16H5.09c.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycosyltransferase 15 family.Curated
Keywords - Domaini
Signal-anchor, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG4472, Eukaryota |
HOGENOMi | CLU_024327_4_1_1 |
InParanoidi | O42944 |
OMAi | DPFQYMQ |
PhylomeDBi | O42944 |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR002685, Glyco_trans_15 IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR31121, PTHR31121, 1 hit |
Pfami | View protein in Pfam PF01793, Glyco_transf_15, 1 hit |
PIRSFi | PIRSF018153, Glyco_trans_15, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
i Sequence
Sequence statusi: Complete.
O42944-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRISRLLIRV LLGFVILFIT YILFPSIPKA LVNTLNVYKL EERLNYYNDR
60 70 80 90 100
LLDGNLKSKE LENATFVTLA RNADLYDLIE TINIYENRFN SKHNYPWVFL
110 120 130 140 150
NDEPFTRTFE VVMSRLTSGP TYFGVVNSSE WDIPKWIDMD IAHSNWNRLS
160 170 180 190 200
REGVLYGGMK SYRQMCRYFS GFFWRHPLLD PYKYYWRVEP STKLLCEVNK
210 220 230 240 250
DPFRQLRLLN KTYGFVITLF EIGQTVPSLW NSTLEFIEKY PETLAKNNLW
260 270 280 290 300
EWISDDNGKK FSHCHFWSNF EIADLDFFRS DSYRKYFDFL DKKGGFFYER
310 320 330 340 350
WGDAPVHSIA LSLFLDRNKL HYFDEIGYSH APLLHCPRKG RCFCKPEEID
360 370
LSSNSSCIAR FINLTNEDYD EL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA17907.1 |
PIRi | T39616 |
RefSeqi | NP_595938.1, NM_001021846.2 |
Genome annotation databases
EnsemblFungii | SPBC16H5.09c.1; SPBC16H5.09c.1:pep; SPBC16H5.09c |
GeneIDi | 2539904 |
KEGGi | spo:SPBC16H5.09c |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA17907.1 |
PIRi | T39616 |
RefSeqi | NP_595938.1, NM_001021846.2 |
3D structure databases
SMRi | O42944 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 276450, 3 interactors |
STRINGi | 4896.SPBC16H5.09c.1 |
Protein family/group databases
CAZyi | GT15, Glycosyltransferase Family 15 |
PTM databases
SwissPalmi | O42944 |
Proteomic databases
MaxQBi | O42944 |
PaxDbi | O42944 |
Genome annotation databases
EnsemblFungii | SPBC16H5.09c.1; SPBC16H5.09c.1:pep; SPBC16H5.09c |
GeneIDi | 2539904 |
KEGGi | spo:SPBC16H5.09c |
Organism-specific databases
PomBasei | SPBC16H5.09c, omh2 |
VEuPathDBi | FungiDB:SPBC16H5.09c |
Phylogenomic databases
eggNOGi | KOG4472, Eukaryota |
HOGENOMi | CLU_024327_4_1_1 |
InParanoidi | O42944 |
OMAi | DPFQYMQ |
PhylomeDBi | O42944 |
Miscellaneous databases
PROi | PR:O42944 |
Family and domain databases
Gene3Di | 3.90.550.10, 1 hit |
InterProi | View protein in InterPro IPR002685, Glyco_trans_15 IPR029044, Nucleotide-diphossugar_trans |
PANTHERi | PTHR31121, PTHR31121, 1 hit |
Pfami | View protein in Pfam PF01793, Glyco_transf_15, 1 hit |
PIRSFi | PIRSF018153, Glyco_trans_15, 1 hit |
SUPFAMi | SSF53448, SSF53448, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | OMH2_SCHPO | |
Accessioni | O42944Primary (citable) accession number: O42944 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 5, 2008 |
Last sequence update: | June 1, 1998 | |
Last modified: | February 23, 2022 | |
This is version 112 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families