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Protein

Chromo domain-containing protein 2

Gene

chp2

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromo domain-containing protein 2
Gene namesi
Name:chp2
ORF Names:SPBC16C6.10
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC16C6.10
PomBaseiSPBC16C6.10 chp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000802391 – 380Chromo domain-containing protein 2Add BLAST380

Proteomic databases

PaxDbiO42934
PRIDEiO42934

PTM databases

iPTMnetiO42934

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi276585, 8 interactors
STRINGi4896.SPBC16C6.10.1

Structurei

3D structure databases

ProteinModelPortaliO42934
SMRiO42934
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini176 – 238ChromoPROSITE-ProRule annotationAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi39 – 151Ser-richAdd BLAST113

Phylogenomic databases

InParanoidiO42934
OrthoDBiEOG092C3CYC
PhylomeDBiO42934

Family and domain databases

CDDicd00024 CHROMO, 1 hit
InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR008251 Chromo_shadow_dom
PfamiView protein in Pfam
PF00385 Chromo, 1 hit
PF01393 Chromo_shadow, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 1 hit
SM00300 ChSh, 1 hit
SUPFAMiSSF54160 SSF54160, 2 hits
PROSITEiView protein in PROSITE
PS50013 CHROMO_2, 1 hit

Sequencei

Sequence statusi: Complete.

O42934-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVKSADLDLM NSIISESDEN FSPPPFTVEE AENSINNKSS TASLESPQNG
60 70 80 90 100
SWHPSLYGLS VPEKTHIQNS LDLYSHGNSG SQKTHNVSFS CEIRKVKSSK
110 120 130 140 150
LSPISNMEDS EDKKEEDESS SYKNEFKSSS SASVSSNFEK TSGSDDHNSQ
160 170 180 190 200
SPVPLNEGFE YIASSGSEDK NSDEEFAVEM ILDSRMKKDG SGFQYYLKWE
210 220 230 240 250
GYDDPSDNTW NDEEDCAGCL ELIDAYWESR GGKPDLSSLI RLTRSRARSS
260 270 280 290 300
NEASYVEKDE SSNSDDSISY KRRRSRNAAN RITDYVDSDL SESSMKEKQS
310 320 330 340 350
KIEKYMKSDK SSKNFKPPFQ KKSWEDLVDC VKTVQQLDNG KLIAKIKWKN
360 370 380
GYVSTHDNII IHQKCPLKII EYYEAHIKFT
Length:380
Mass (Da):42,955
Last modified:June 1, 1998 - v1
Checksum:iA2D96BD5987807C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA16917.1
PIRiT39561
RefSeqiNP_596808.1, NM_001023829.2

Genome annotation databases

EnsemblFungiiSPBC16C6.10.1; SPBC16C6.10.1:pep; SPBC16C6.10
GeneIDi2540047
KEGGispo:SPBC16C6.10

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA16917.1
PIRiT39561
RefSeqiNP_596808.1, NM_001023829.2

3D structure databases

ProteinModelPortaliO42934
SMRiO42934
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276585, 8 interactors
STRINGi4896.SPBC16C6.10.1

PTM databases

iPTMnetiO42934

Proteomic databases

PaxDbiO42934
PRIDEiO42934

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC16C6.10.1; SPBC16C6.10.1:pep; SPBC16C6.10
GeneIDi2540047
KEGGispo:SPBC16C6.10

Organism-specific databases

EuPathDBiFungiDB:SPBC16C6.10
PomBaseiSPBC16C6.10 chp2

Phylogenomic databases

InParanoidiO42934
OrthoDBiEOG092C3CYC
PhylomeDBiO42934

Miscellaneous databases

PROiPR:O42934

Family and domain databases

CDDicd00024 CHROMO, 1 hit
InterProiView protein in InterPro
IPR016197 Chromo-like_dom_sf
IPR000953 Chromo/chromo_shadow_dom
IPR023780 Chromo_domain
IPR008251 Chromo_shadow_dom
PfamiView protein in Pfam
PF00385 Chromo, 1 hit
PF01393 Chromo_shadow, 1 hit
SMARTiView protein in SMART
SM00298 CHROMO, 1 hit
SM00300 ChSh, 1 hit
SUPFAMiSSF54160 SSF54160, 2 hits
PROSITEiView protein in PROSITE
PS50013 CHROMO_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCHP2_SCHPO
AccessioniPrimary (citable) accession number: O42934
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 13, 2005
Last sequence update: June 1, 1998
Last modified: February 28, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
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Main funding by: National Institutes of Health

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