SPAC4F10.16c

Functionⁱ

Catalyzes the hydrolysis of ATP coupled with the transport of phospholipids.By similarity

Catalytic activityⁱ

ATP + H₂O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	600	4-aspartylphosphate intermediateBy similarity		1

GO - Molecular functionⁱ

ATP binding Source: UniProtKB-KW
magnesium ion binding Source: InterPro
phospholipid-translocating ATPase activity Source: PomBase

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

Golgi vesicle budding Source: GO_Central
phospholipid translocation Source: PomBase

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase
Biological process	Lipid transport, Transport
Ligand	ATP-binding, Magnesium, Nucleotide-binding

Enzyme and pathway databases

Reactomeⁱ	R-SPO-936837 Ion transport by P-type ATPases

Reactomeⁱ

R-SPO-936837 Ion transport by P-type ATPases

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Putative phospholipid-transporting ATPase C4F10.16c (EC:3.6.3.1)
Gene namesⁱ	ORF Names:SPAC4F10.16c
Organismⁱ	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifierⁱ	284812 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe
Proteomesⁱ	UP000002485 Componentⁱ: Chromosome I

Organism-specific databases

EuPathDBⁱ	FungiDB:SPAC4F10.16c
PomBaseⁱ	SPAC4F10.16c

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 154	CytoplasmicSequence analysisAdd BLAST	154
Transmembraneⁱ	155 – 172	HelicalSequence analysisAdd BLAST	18
Topological domainⁱ	173 – 177	LumenalSequence analysis	5
Transmembraneⁱ	178 – 197	HelicalSequence analysisAdd BLAST	20
Topological domainⁱ	198 – 482	CytoplasmicSequence analysisAdd BLAST	285
Transmembraneⁱ	483 – 503	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	504 – 531	LumenalSequence analysisAdd BLAST	28
Transmembraneⁱ	532 – 552	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	553 – 1091	CytoplasmicSequence analysisAdd BLAST	539
Transmembraneⁱ	1092 – 1112	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	1113 – 1124	LumenalSequence analysisAdd BLAST	12
Transmembraneⁱ	1125 – 1145	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	1146 – 1174	CytoplasmicSequence analysisAdd BLAST	29
Transmembraneⁱ	1175 – 1197	HelicalSequence analysisAdd BLAST	23
Topological domainⁱ	1198 – 1212	LumenalSequence analysisAdd BLAST	15
Transmembraneⁱ	1213 – 1233	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	1234 – 1240	CytoplasmicSequence analysis	7
Transmembraneⁱ	1241 – 1261	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	1262 – 1276	LumenalSequence analysisAdd BLAST	15
Transmembraneⁱ	1277 – 1297	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	1298 – 1367	CytoplasmicSequence analysisAdd BLAST	70

Keywords - Cellular componentⁱ

Endoplasmic reticulum, Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000343137	1 – 1367	Putative phospholipid-transporting ATPase C4F10.16cAdd BLAST		1367

Proteomic databases

PaxDbⁱ	O36028
PRIDEⁱ	O36028

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	279941, 8 interactors
STRINGⁱ	4896.SPAC4F10.16c.1

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O36028
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. [View classification]Curated

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMⁱ	HOG000202528
InParanoidⁱ	O36028
KEGG Orthology (KO) More...KOⁱ	K01530
Database of Orthologous Groups More...OrthoDBⁱ	EOG092C0BQ4
PhylomeDBⁱ	O36028

Family and domain databases

Gene3Dⁱ	3.40.50.1000, 1 hit
InterProⁱ	View protein in InterPro IPR023299 ATPase_P-typ_cyto_dom_N IPR018303 ATPase_P-typ_P_site IPR023298 ATPase_P-typ_TM_dom_sf IPR008250 ATPase_P-typ_transduc_dom_A_sf IPR036412 HAD-like_sf IPR023214 HAD_sf IPR006539 P-type_ATPase_IV IPR032631 P-type_ATPase_N IPR001757 P_typ_ATPase IPR032630 P_typ_ATPase_c IPR026871 PLip_transp_ATPase
PANTHERⁱ	PTHR24092 PTHR24092, 1 hit PTHR24092:SF34 PTHR24092:SF34, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF16212 PhoLip_ATPase_C, 1 hit PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMⁱ	SSF56784 SSF56784, 2 hits SSF81653 SSF81653, 2 hits SSF81660 SSF81660, 2 hits SSF81665 SSF81665, 3 hits
TIGRFAMsⁱ	TIGR01652 ATPase-Plipid, 1 hit TIGR01494 ATPase_P-type, 1 hit
PROSITEⁱ	View protein in PROSITE PS00154 ATPASE_E1_E2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

O36028-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPSLINFDAI SSLKSSLHGL SICAFNHLHH VPQHNGSLAH EGPTNQTDYS 
        60         70         80         90        100
SRHHESQFSQ EAHAEQRSRD DEEANSFEGS CNNSDQSWTS RVTSKKNEAG 
       110        120        130        140        150
TESGDASVRR IYVTSIPEEH RHLPSQWFPS NKIRTTKYTP VSFIPKNLWN 
       160        170        180        190        200
QFKNIANAFF LFVTLLQCIP LFCPEHLGLS FIPLSVILLT TAIKDGIEDY 
       210        220        230        240        250
RRCVLDKKFN NTLTWKLVGF NNANALGEHI GLWRKLKKFI SHTVADMSYC 
       260        270        280        290        300
LKNSGISSGL ATLTVDNISH RHSLESDSAF TLSSVSQDSL EIHEIGNSGP 
       310        320        330        340        350
SNSFSVIQEQ STGSSNAKFE RVCRKSLLVG DIVKVLADEA IPADLLILST 
       360        370        380        390        400
ENSNGVCYVE TKNLDGETNL KDKYALCSTK CCKSEYRCSA ASFWVECEQP 
       410        420        430        440        450
HADLYSLNGV VKAPGAVQSP SESTNGRKIH EEPFSISNVL LCGCTLRNSK 
       460        470        480        490        500
WVIGLVLYTG SETRIQKNRG LTPSKRSRIT RDLNWTIILN FLLLFAMCLF 
       510        520        530        540        550
SGVLRSIYSA QNNSARVFEL SKNSNTAPAH GIISIFTSLI LFQNLVPISL 
       560        570        580        590        600
YITMDIVRSI QSYFIFSDRE MYDEKLDCPC SPKSWNISDD LGQIEYIFSD 
       610        620        630        640        650
KTGTLTQNIM SFKKCSINGI RYGKSHNEDT CIKKRRNLNY NENLSCKVDL 
       660        670        680        690        700
DKKKMLETLS LSDSPNPESI TFISSKFVDH LQSNENYIQT EACFEFFKAL 
       710        720        730        740        750
ALCHSVVTDV QDETLIYNAQ SPDEEALVKV ARDFGFTLLN TKNRRYTIRI 
       760        770        780        790        800
RGENKNFRVL DIIPFTSTRK RMSVIIRDED GIIHLICKGA DTVIFPRLSS 
       810        820        830        840        850
GQNNIIEKTK KHLASFSSEG FRTLCIARRT IDKQDYLEWK VNFNEANSAI 
       860        870        880        890        900
HERNEKVSKV SEMIEQELEL LGGTAIEDKL QENVPETIAL LAIAGIKLWV 
       910        920        930        940        950
LTGDKVETAI NIGYSCNLLD PNMTIFRIDA NSFGALEEVE AFIRNTLCFN 
       960        970        980        990       1000
FGYMGTDEEF RFLLKDHSPP SPKHAIVIDG DALNFVLSEQ VSFLFLMLCK 
      1010       1020       1030       1040       1050
QCKTVLCCRV SPSQKAAVVA LVKKSLNVVT LAIGDGANDV SMIQEADVGV 
      1060       1070       1080       1090       1100
GIKGVEGQAA SMSADYAIGQ FSFLGRLLLV HGRWDYKRMS QMISFFFYKN 
      1110       1120       1130       1140       1150
VIWTFILFWY QFYNEFDGNY IFDYTYVMLF NLLFTSLPVI IAGCFDQDVD 
      1160       1170       1180       1190       1200
ASVSMKNPSL YQRGILGLEW NGKRFWSYML DGIYQSLVCF GVALFVFKFG 
      1210       1220       1230       1240       1250
DFVSWTGRNI ECIEDIGLFI SSPTIFVINI FILMNQERLN LISLITWMFS 
      1260       1270       1280       1290       1300
IGVFWIWTFI YSEVGPSYAF HKSASRTCQT FGFWCVTVLT IALCLLPRFS 
      1310       1320       1330       1340       1350
YICLQKLFYP RDIDLLRRRL CAKSDDETSS SSSFATDIEM CEQCNDPLSS 
      1360 
KKNSGIVTSV SFDDSNK

Length:1,367

Mass (Da):154,282

Last modified:January 1, 1998 - v1

Checksum:ⁱ4DCFD8A7479465EB

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CU329670 Genomic DNA Translation: CAB11719.1
PIRⁱ	T38820
NCBI Reference Sequences More...RefSeqⁱ	NP_594759.1, NM_001020186.2

Genome annotation databases

EnsemblFungiⁱ	SPAC4F10.16c.1; SPAC4F10.16c.1:pep; SPAC4F10.16c
GeneIDⁱ	2543523
KEGGⁱ	spo:SPAC4F10.16c

Similar proteinsⁱ

50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O36028	Phospholipid-transporting ATPase		SCHCR		1376	UniRef50_O36028
Phospholipid-transporting ATPase		SCHJY		1364
Phospholipid-transporting ATPase		SCHOY		1382

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CU329670 Genomic DNA Translation: CAB11719.1
PIRⁱ	T38820
RefSeqⁱ	NP_594759.1, NM_001020186.2

3D structure databases

ProteinModelPortalⁱ	O36028
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	279941, 8 interactors
STRINGⁱ	4896.SPAC4F10.16c.1

Proteomic databases

PaxDbⁱ	O36028
PRIDEⁱ	O36028

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblFungiⁱ	SPAC4F10.16c.1; SPAC4F10.16c.1:pep; SPAC4F10.16c
GeneIDⁱ	2543523
KEGGⁱ	spo:SPAC4F10.16c

Organism-specific databases

EuPathDBⁱ	FungiDB:SPAC4F10.16c
PomBaseⁱ	SPAC4F10.16c

Phylogenomic databases

HOGENOMⁱ	HOG000202528
InParanoidⁱ	O36028
KOⁱ	K01530
OrthoDBⁱ	EOG092C0BQ4
PhylomeDBⁱ	O36028

Enzyme and pathway databases

Reactomeⁱ	R-SPO-936837 Ion transport by P-type ATPases

Reactomeⁱ

R-SPO-936837 Ion transport by P-type ATPases

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:O36028

PROⁱ

PR:O36028

Family and domain databases

Gene3Dⁱ	3.40.50.1000, 1 hit
InterProⁱ	View protein in InterPro IPR023299 ATPase_P-typ_cyto_dom_N IPR018303 ATPase_P-typ_P_site IPR023298 ATPase_P-typ_TM_dom_sf IPR008250 ATPase_P-typ_transduc_dom_A_sf IPR036412 HAD-like_sf IPR023214 HAD_sf IPR006539 P-type_ATPase_IV IPR032631 P-type_ATPase_N IPR001757 P_typ_ATPase IPR032630 P_typ_ATPase_c IPR026871 PLip_transp_ATPase
PANTHERⁱ	PTHR24092 PTHR24092, 1 hit PTHR24092:SF34 PTHR24092:SF34, 1 hit
Pfamⁱ	View protein in Pfam PF16212 PhoLip_ATPase_C, 1 hit PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMⁱ	SSF56784 SSF56784, 2 hits SSF81653 SSF81653, 2 hits SSF81660 SSF81660, 2 hits SSF81665 SSF81665, 3 hits
TIGRFAMsⁱ	TIGR01652 ATPase-Plipid, 1 hit TIGR01494 ATPase_P-type, 1 hit
PROSITEⁱ	View protein in PROSITE PS00154 ATPASE_E1_E2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ATCZ_SCHPO
Accessionⁱ	O36028Primary (citable) accession number: O36028
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
	Last sequence update:	January 1, 1998
	Last modified:	July 18, 2018
	This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Fungal Protein Annotation Program

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UniProtKB - O36028 (ATCZ_SCHPO)

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Putative phospholipid-transporting ATPase C4F10.16c

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Endoplasmic reticulum

Endoplasmic reticulum

Golgi apparatus

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ