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Protein

39S ribosomal protein L23, mitochondrial

Gene

Mrpl23

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • mitochondrial translation Source: GO_Central
  • translation Source: MGI

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L23, mitochondrial
Short name:
L23mt
Short name:
MRP-L23
Alternative name(s):
L23 mitochondrial-related protein
Gene namesi
Name:Mrpl23
Synonyms:L23mrp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1196612 Mrpl23

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001294851 – 14639S ribosomal protein L23, mitochondrialAdd BLAST146

Proteomic databases

EPDiO35972
MaxQBiO35972
PaxDbiO35972
PeptideAtlasiO35972
PRIDEiO35972

PTM databases

iPTMnetiO35972
PhosphoSitePlusiO35972

Expressioni

Gene expression databases

BgeeiENSMUSG00000037772 Expressed in 22 organ(s), highest expression level in brown adipose tissue
CleanExiMM_MRPL23
ExpressionAtlasiO35972 baseline and differential
GenevisibleiO35972 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi202972, 1 interactor
DIPiDIP-61654N
IntActiO35972, 1 interactor
STRINGi10090.ENSMUSP00000039784

Structurei

3D structure databases

ProteinModelPortaliO35972
SMRiO35972
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG4089 Eukaryota
ENOG4111IAB LUCA
GeneTreeiENSGT00390000007739
HOGENOMiHOG000231896
HOVERGENiHBG052914
InParanoidiO35972
KOiK02892
OMAiEMTKYDV
OrthoDBiEOG091G16EY
PhylomeDBiO35972
TreeFamiTF105852

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR012678 Ribosomal_L23/L15e_core_dom_sf
IPR013025 Ribosomal_L25/23
PfamiView protein in Pfam
PF00276 Ribosomal_L23, 1 hit
SUPFAMiSSF54189 SSF54189, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

O35972-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MARNVLYPLY QLGGPQLRVF RTNFFIQLVR PGTAQPEDTV QFRIPMEMTR
60 70 80 90 100
VDLRNYLEQI YNVPVAAVRT RVQHGSNRRR DHKNVRIKKP DYKVAYVQLA
110 120 130 140
HGQTFTFPDL FPEKDPRSPE PLEEELPQQR QSSDLRCPGI PSWFGL
Length:146
Mass (Da):17,122
Last modified:January 1, 1998 - v1
Checksum:i0116ADE56C9B1553
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GSZ9A0A1B0GSZ9_MOUSE
39S ribosomal protein L23, mitochon...
Mrpl23
172Annotation score:
A0A1B0GQZ1A0A1B0GQZ1_MOUSE
39S ribosomal protein L23, mitochon...
Mrpl23 mCG_130909
101Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U84902 mRNA Translation: AAC53392.1
U84903 Genomic DNA Translation: AAC53393.1
AB049646 mRNA Translation: BAB40851.1
AK086805 mRNA Translation: BAC39746.1
BC081460 mRNA Translation: AAH81460.1
U71209 Genomic DNA Translation: AAB70459.1
CCDSiCCDS22032.1
RefSeqiNP_035418.1, NM_011288.1
UniGeneiMm.12144

Genome annotation databases

EnsembliENSMUST00000038675; ENSMUSP00000039784; ENSMUSG00000037772
GeneIDi19935
KEGGimmu:19935
UCSCiuc009kny.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U84902 mRNA Translation: AAC53392.1
U84903 Genomic DNA Translation: AAC53393.1
AB049646 mRNA Translation: BAB40851.1
AK086805 mRNA Translation: BAC39746.1
BC081460 mRNA Translation: AAH81460.1
U71209 Genomic DNA Translation: AAB70459.1
CCDSiCCDS22032.1
RefSeqiNP_035418.1, NM_011288.1
UniGeneiMm.12144

3D structure databases

ProteinModelPortaliO35972
SMRiO35972
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi202972, 1 interactor
DIPiDIP-61654N
IntActiO35972, 1 interactor
STRINGi10090.ENSMUSP00000039784

PTM databases

iPTMnetiO35972
PhosphoSitePlusiO35972

Proteomic databases

EPDiO35972
MaxQBiO35972
PaxDbiO35972
PeptideAtlasiO35972
PRIDEiO35972

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000038675; ENSMUSP00000039784; ENSMUSG00000037772
GeneIDi19935
KEGGimmu:19935
UCSCiuc009kny.1 mouse

Organism-specific databases

CTDi6150
MGIiMGI:1196612 Mrpl23

Phylogenomic databases

eggNOGiKOG4089 Eukaryota
ENOG4111IAB LUCA
GeneTreeiENSGT00390000007739
HOGENOMiHOG000231896
HOVERGENiHBG052914
InParanoidiO35972
KOiK02892
OMAiEMTKYDV
OrthoDBiEOG091G16EY
PhylomeDBiO35972
TreeFamiTF105852

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Miscellaneous databases

PROiPR:O35972
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000037772 Expressed in 22 organ(s), highest expression level in brown adipose tissue
CleanExiMM_MRPL23
ExpressionAtlasiO35972 baseline and differential
GenevisibleiO35972 MM

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR012678 Ribosomal_L23/L15e_core_dom_sf
IPR013025 Ribosomal_L25/23
PfamiView protein in Pfam
PF00276 Ribosomal_L23, 1 hit
SUPFAMiSSF54189 SSF54189, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiRM23_MOUSE
AccessioniPrimary (citable) accession number: O35972
Secondary accession number(s): Q78E46
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: January 1, 1998
Last modified: November 7, 2018
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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