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Protein

28S ribosomal protein S12, mitochondrial

Gene

Mrps12

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: UniProtKB

GO - Biological processi

  • mitochondrial translation Source: UniProtKB
  • translation Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840 Mitochondrial translation elongation
R-MMU-5419276 Mitochondrial translation termination

Names & Taxonomyi

Protein namesi
Recommended name:
28S ribosomal protein S12, mitochondrial
Short name:
MRP-S12
Short name:
S12mt
Alternative name(s):
MT-RPS12
Gene namesi
Name:Mrps12
Synonyms:Rpms12
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1346333 Mrps12

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 29MitochondrionSequence analysisAdd BLAST29
ChainiPRO_000003060730 – 13928S ribosomal protein S12, mitochondrialAdd BLAST110

Proteomic databases

EPDiO35680
MaxQBiO35680
PaxDbiO35680
PeptideAtlasiO35680
PRIDEiO35680

PTM databases

iPTMnetiO35680
PhosphoSitePlusiO35680

Expressioni

Gene expression databases

BgeeiENSMUSG00000045948
CleanExiMM_MRPS12
ExpressionAtlasiO35680 baseline and differential
GenevisibleiO35680 MM

Interactioni

Subunit structurei

Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.By similarity

Protein-protein interaction databases

BioGridi204858, 1 interactor
STRINGi10090.ENSMUSP00000062066

Structurei

3D structure databases

ProteinModelPortaliO35680
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG1750 Eukaryota
COG0048 LUCA
GeneTreeiENSGT00550000075103
HOGENOMiHOG000040063
HOVERGENiHBG001525
InParanoidiO35680
KOiK02950
OMAiHSLQEHH
OrthoDBiEOG091G0U3U
PhylomeDBiO35680
TreeFamiTF315095

Family and domain databases

CDDicd03368 Ribosomal_S12, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR006032 Ribosomal_S12/S23
IPR005679 Ribosomal_S12_bac
PANTHERiPTHR11652 PTHR11652, 1 hit
PfamiView protein in Pfam
PF00164 Ribosom_S12_S23, 1 hit
PIRSFiPIRSF002133 Ribosomal_S12/S23, 1 hit
PRINTSiPR01034 RIBOSOMALS12
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00981 rpsL_bact, 1 hit
PROSITEiView protein in PROSITE
PS00055 RIBOSOMAL_S12, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O35680-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSWPGLLYGL TTSLSRGLAL APQLWAARSM ATLNQMHRLG PRKEPPKRLG
60 70 80 90 100
PTEGRPQLKG VVLRTFIRKP KKPNSANRKC CRVRLSTGKE AVCFIPGEGH
110 120 130
TLQEHHVVLV EGGRTQDLPG VKLKVVRGKY DCGHVQKKK
Length:139
Mass (Da):15,437
Last modified:January 1, 1998 - v1
Checksum:iB365FE940025EA08
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11682 mRNA Translation: CAA72378.1
BC012679 mRNA Translation: AAH12679.1
BC027522 mRNA Translation: AAH27522.1
CCDSiCCDS21052.1
RefSeqiNP_036015.1, NM_011885.4
XP_006539971.1, XM_006539908.2
UniGeneiMm.358650

Genome annotation databases

EnsembliENSMUST00000056078; ENSMUSP00000062066; ENSMUSG00000045948
ENSMUST00000171183; ENSMUSP00000132443; ENSMUSG00000045948
GeneIDi24030
KEGGimmu:24030
UCSCiuc009fzo.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRT12_MOUSE
AccessioniPrimary (citable) accession number: O35680
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

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