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Entry version 119 (08 May 2019)
Sequence version 2 (20 Feb 2007)
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Protein

Secretogranin-1

Gene

Chgb

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-RNO-8957275 Post-translational protein phosphorylation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Secretogranin-1
Alternative name(s):
Chromogranin-B
Short name:
CgB
Glucagonoma peptide
Secretogranin-I
Short name:
SgI
Cleaved into the following 3 chains:
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Chgb
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Rat genome database

More...
RGDi
2339 Chgb

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 201 PublicationAdd BLAST20
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000544621 – 675Secretogranin-1Add BLAST655
<p>This subsection of the ‘PTM / Processing’ section describes the position and length of an active peptide in the mature protein.<p><a href='/help/peptide' target='_top'>More...</a></p>PeptideiPRO_0000432733572 – 582PE-11By similarityAdd BLAST11
PeptideiPRO_0000411990615 – 675CCB peptide long formAdd BLAST61
PeptideiPRO_0000005447615 – 674CCB peptide short formAdd BLAST60

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi36 ↔ 57By similarity
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei93PhosphoserineCombined sources1
Modified residuei99PhosphoserineSequence analysis1
Modified residuei100PhosphoserineSequence analysis1
Modified residuei129PhosphoserineCombined sources1
Modified residuei147PhosphoserineCombined sources1
Modified residuei190PhosphoserineCombined sources1
Modified residuei255PhosphoserineCombined sources1
Modified residuei259PhosphoserineCombined sources1
Modified residuei291PhosphoserineSequence analysis1
Modified residuei309PhosphoserineBy similarity1
Modified residuei333PhosphoserineCombined sources1
Modified residuei339Sulfotyrosine1 Publication1
Modified residuei362PhosphoserineBy similarity1
Modified residuei372PhosphoserineBy similarity1
Modified residuei375PhosphoserineCombined sources1
Modified residuei397PhosphoserineSequence analysis1
Modified residuei469SulfotyrosineBy similarity1
Modified residuei490PhosphoserineCombined sources1
Modified residuei529PhosphoserineSequence analysis1
Modified residuei540PhosphoserineSequence analysis1
Modified residuei563SulfotyrosineBy similarity1
Modified residuei622Sulfotyrosine; partial1 Publication1
Modified residuei624PhosphoserineCombined sources1 Publication1
Modified residuei674Arginine amide; in CCB peptide short form1 Publication1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Extensively processed in glucagonoma tissue by limited proteolysis at conserved basic residues. Alternative processing are seen in different tissues. The proglucagon-converting enzymes present in transformed alpha-cells are likely candidates to be involved in tissue-specific processing.

Keywords - PTMi

Amidation, Cleavage on pair of basic residues, Disulfide bond, Phosphoprotein, Sulfation

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
O35314

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O35314

PRoteomics IDEntifications database

More...
PRIDEi
O35314

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O35314

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O35314

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in the brain, adrenal medulla and anterior pituitary. In the brain, localized to the hippocampal formation, the endocrine hypothalamus, the olfactory system, and in anatomically distinct structures in the pons-medulla.1 Publication

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

First expressed in the brain around embryonic days 13-14, and peaks by postnatal day 20.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000021269 Expressed in 5 organ(s), highest expression level in brain

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O35314 RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
O35314, 2 interactors

Molecular INTeraction database

More...
MINTi
O35314

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000028892

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi162 – 167Poly-Glu6

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IVJ3 Eukaryota
ENOG410ZHMS LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154206

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000132984

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O35314

KEGG Orthology (KO)

More...
KOi
K19991

Identification of Orthologs from Complete Genome Data

More...
OMAi
MDDNFLE

Database of Orthologous Groups

More...
OrthoDBi
670416at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O35314

TreeFam database of animal gene trees

More...
TreeFami
TF336596

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001819 Chromogranin_AB
IPR018054 Chromogranin_CS
IPR001990 Granin

The PANTHER Classification System

More...
PANTHERi
PTHR10583 PTHR10583, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01271 Granin, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00659 CHROMOGRANIN

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00422 GRANINS_1, 1 hit
PS00423 GRANINS_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

O35314-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQRAMLLGLL GAAALAAVIS APVDNRDHNE EMVTRCIIEV LSNALSKSSA
60 70 80 90 100
PTITPECRQV LRKSGKEVKG EEKGENENSK FEVRLLRDPS DASVGRWASS
110 120 130 140 150
REETGAPVED SPGQAKVDNE EWTGGGGHSR EAVDDQESLH PSNQQVSKEA
160 170 180 190 200
KIRHSEERGG KEEEEEEGKI YPKGEHRGDA GEEKKHTEES GEKHNAFSNK
210 220 230 240 250
RSEASAKKKE ESVARAEAHF VELEKTHSRE QSSQESGEET RRQEKPQELP
260 270 280 290 300
DQDQSEEESE EGEEGEEGAT SEVTKRRPRH HHWRSQSNKP SYEGRRPLSE
310 320 330 340 350
ERKHAAGESK DANVATANLG EKRGHHLAHY RASEEEPDYG EELRSYPGFQ
360 370 380 390 400
APQGLQYQGR GSEEVRAPSP RSEESQEKEY KRNHPDSELE STANRHSEET
410 420 430 440 450
EEERSYEGAK GRQHRGRGRE PGAYPALDSR QEKRLLDEGH DPVHESPVDT
460 470 480 490 500
AKRYPQSKWQ EQEKNYLNYD EEGDQGRWWQ QEEQLEPEES REEVSFPDRQ
510 520 530 540 550
YAPYPTTEKR KRLGALFNPY FDPLQWKNSD FEKKGNPDDS FLDDDGEDGN
560 570 580 590 600
GVTMTEKNFF PEYNYDWWEK RPFSEDVNWG YEKRSFARAP HLDLKRQYDD
610 620 630 640 650
GVAELDQLLH YRKKAAEFPD FYDSEEQMGP HQEAEDEKDR ADQRVLTEEE
660 670
KKELENLAAM DLELQKIAEK FSQRG
Length:675
Mass (Da):77,536
Last modified:February 20, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i042B045B272074FC
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti358Q → R in AAB72089 (PubMed:2641278).Curated1
Sequence conflicti461 – 464EQEK → GQGE in AAB72089 (PubMed:2641278).Curated4
Sequence conflicti588R → K in AAB72089 (PubMed:2641278).Curated1

<p>This subsection of the ‘Sequence’ section reports information derived from mass spectrometry experiments done on the entire protein or on biologically active derived peptide(s).<p><a href='/help/mass_spectrometry' target='_top'>More...</a></p>Mass spectrometryi

Molecular mass is 7270.2446 Da from positions 615 - 675. Determined by MALDI. Sulfated and phosphorylated CCB peptide long form.1 Publication
Molecular mass is 7190.3133 Da from positions 615 - 675. Determined by MALDI. Sulfated or phosphorylated CCB peptide long form.1 Publication
Molecular mass is 7110.2525 Da from positions 615 - 675. Determined by MALDI. CCB peptide long form without any modifications.1 Publication
Molecular mass is 7212.2845 Da from positions 615 - 674. Determined by MALDI. Sulfated and phosphorylated CCB peptide short form.1 Publication
Molecular mass is 7132.2800 Da from positions 615 - 674. Determined by MALDI. Sulfated or phosphorylated CCB peptide short form.1 Publication
Molecular mass is 7052.3410 Da from positions 615 - 674. Determined by MALDI. CCB peptide short form without any modifications.1 Publication

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF019974 mRNA Translation: AAB72089.1
BC128743 mRNA Translation: AAI28744.1

Protein sequence database of the Protein Information Resource

More...
PIRi
D49164

NCBI Reference Sequences

More...
RefSeqi
NP_036658.2, NM_012526.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000028892; ENSRNOP00000028892; ENSRNOG00000021269

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
24259

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:24259

UCSC genome browser

More...
UCSCi
RGD:2339 rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF019974 mRNA Translation: AAB72089.1
BC128743 mRNA Translation: AAI28744.1
PIRiD49164
RefSeqiNP_036658.2, NM_012526.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

IntActiO35314, 2 interactors
MINTiO35314
STRINGi10116.ENSRNOP00000028892

PTM databases

iPTMnetiO35314
PhosphoSitePlusiO35314

Proteomic databases

jPOSTiO35314
PaxDbiO35314
PRIDEiO35314

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000028892; ENSRNOP00000028892; ENSRNOG00000021269
GeneIDi24259
KEGGirno:24259
UCSCiRGD:2339 rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1114
RGDi2339 Chgb

Phylogenomic databases

eggNOGiENOG410IVJ3 Eukaryota
ENOG410ZHMS LUCA
GeneTreeiENSGT00940000154206
HOGENOMiHOG000132984
InParanoidiO35314
KOiK19991
OMAiMDDNFLE
OrthoDBi670416at2759
PhylomeDBiO35314
TreeFamiTF336596

Enzyme and pathway databases

ReactomeiR-RNO-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-RNO-8957275 Post-translational protein phosphorylation

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O35314

Gene expression databases

BgeeiENSRNOG00000021269 Expressed in 5 organ(s), highest expression level in brain
GenevisibleiO35314 RN

Family and domain databases

InterProiView protein in InterPro
IPR001819 Chromogranin_AB
IPR018054 Chromogranin_CS
IPR001990 Granin
PANTHERiPTHR10583 PTHR10583, 1 hit
PfamiView protein in Pfam
PF01271 Granin, 1 hit
PRINTSiPR00659 CHROMOGRANIN
PROSITEiView protein in PROSITE
PS00422 GRANINS_1, 1 hit
PS00423 GRANINS_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCG1_RAT
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O35314
Secondary accession number(s): A1A5N9, Q9QVG8, Q9QVH1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: February 20, 2007
Last modified: May 8, 2019
This is version 119 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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