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UniProtKB - O35305 (TNR11_MOUSE)

Entry version 155 (07 Apr 2021)
Sequence version 1 (01 Jan 1998)
Previous versions | rss
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Protein

Tumor necrosis factor receptor superfamily member 11A

Gene

Tnfrsf11a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi134Sodium; via carbonyl oxygen1
Metal bindingi135Sodium; via carbonyl oxygen1
Metal bindingi138Sodium; via carbonyl oxygen1
Metal bindingi161Sodium; via carbonyl oxygen1
Metal bindingi163Sodium; via carbonyl oxygen1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
LigandMetal-binding, Sodium

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-5668541, TNFR2 non-canonical NF-kB pathway
R-MMU-5676594, TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tumor necrosis factor receptor superfamily member 11A
Alternative name(s):
Osteoclast differentiation factor receptor
Short name:
ODFR
Receptor activator of NF-KB
CD_antigen: CD265
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tnfrsf11a
Synonyms:Rank
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1314891, Tnfrsf11a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini31 – 214ExtracellularSequence analysisAdd BLAST184
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei215 – 234HelicalSequence analysisAdd BLAST20
Topological domaini235 – 625CytoplasmicSequence analysisAdd BLAST391

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 30Sequence analysisAdd BLAST30
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003458631 – 625Tumor necrosis factor receptor superfamily member 11AAdd BLAST595

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi35 ↔ 47
Disulfide bondi48 ↔ 61
Disulfide bondi51 ↔ 69
Disulfide bondi72 ↔ 87
Disulfide bondi93 ↔ 113
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi106N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi115 ↔ 128
Disulfide bondi125 ↔ 127
Disulfide bondi134 ↔ 152
Disulfide bondi155 ↔ 170
Glycosylationi175N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi176 ↔ 195
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei571PhosphoserineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		O35305

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O35305

PeptideAtlas

More...PeptideAtlasi		O35305

PRoteomics IDEntifications database

More...PRIDEi		O35305

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		260632

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		O35305, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O35305

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O35305

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Ubiquitous expression with high levels in trabecular bone, thymus, small intestine, lung, brain and kidney. Weakly expressed in spleen and bone marrow.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000026321, Expressed in submandibular gland and 136 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O35305, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to the clefts between the subunits of the TNFSF11 ligand trimer to form a heterohexamer.

Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6 (By similarity).

Interacts (via cytoplasmic domain) with GAB2 (By similarity).

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		204246, 4 interactors

Database of interacting proteins

More...DIPi		DIP-48710N

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...ELMi		O35305

Protein interaction database and analysis system

More...IntActi		O35305, 11 interactors

Molecular INTeraction database

More...MINTi		O35305

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000027559

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O35305, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1625
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O35305

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		O35305

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati35 – 69TNFR-Cys 1Add BLAST35
Repeati72 – 113TNFR-Cys 2Add BLAST42
Repeati115 – 152TNFR-Cys 3Add BLAST38
Repeati155 – 195TNFR-Cys 4Add BLAST41

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502RWJI, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000161211

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_026571_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O35305

Identification of Orthologs from Complete Genome Data

More...OMAi		FRGWITC

Database of Orthologous Groups

More...OrthoDBi		1038336at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O35305

TreeFam database of animal gene trees

More...TreeFami		TF331157

Family and domain databases

Conserved Domains Database

More...CDDi		cd13411, TNFRSF11A, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR041648, RANK_CRD_2
IPR001368, TNFR/NGFR_Cys_rich_reg
IPR022323, TNFR_11
IPR022361, TNFR_11A
IPR034040, TNFRSF11A_N

Pfam protein domain database

More...Pfami		View protein in Pfam
PF18278, RANK_CRD_2, 1 hit
PF00020, TNFR_c6, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01961, TNFACTORR11
PR01974, TNFACTORR11A

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00208, TNFR, 4 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00652, TNFR_NGFR_1, 1 hit
PS50050, TNFR_NGFR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

O35305-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPRARRRRQ LPAPLLALCV LLVPLQVTLQ VTPPCTQERH YEHLGRCCSR 
        60         70         80         90        100
CEPGKYLSSK CTPTSDSVCL PCGPDEYLDT WNEEDKCLLH KVCDAGKALV 
       110        120        130        140        150
AVDPGNHTAP RRCACTAGYH WNSDCECCRR NTECAPGFGA QHPLQLNKDT 
       160        170        180        190        200
VCTPCLLGFF SDVFSSTDKC KPWTNCTLLG KLEAHQGTTE SDVVCSSSMT 
       210        220        230        240        250
LRRPPKEAQA YLPSLIVLLL FISVVVVAAI IFGVYYRKGG KALTANLWNW 
       260        270        280        290        300
VNDACSSLSG NKESSGDRCA GSHSATSSQQ EVCEGILLMT REEKMVPEDG 
       310        320        330        340        350
AGVCGPVCAA GGPWAEVRDS RTFTLVSEVE TQGDLSRKIP TEDEYTDRPS 
       360        370        380        390        400
QPSTGSLLLI QQGSKSIPPF QEPLEVGEND SLSQCFTGTE STVDSEGCDF 
       410        420        430        440        450
TEPPSRTDSM PVSPEKHLTK EIEGDSCLPW VVSSNSTDGY TGSGNTPGED 
       460        470        480        490        500
HEPFPGSLKC GPLPQCAYSM GFPSEAAASM AEAGVRPQDR ADERGASGSG 
       510        520        530        540        550
SSPSDQPPAS GNVTGNSNST FISSGQVMNF KGDIIVVYVS QTSQEGPGSA 
       560        570        580        590        600
EPESEPVGRP VQEETLAHRD SFAGTAPRFP DVCATGAGLQ EQGAPRQKDG 
       610        620 
TSRPVQEQGG AQTSLHTQGS GQCAE
Length:625
Mass (Da):66,621
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF8C1872E99511D8E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti494R → K in AAH19185 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF019046 mRNA Translation: AAB86810.1
BC019185 mRNA Translation: AAH19185.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS15207.1

NCBI Reference Sequences

More...RefSeqi		NP_033425.3, NM_009399.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000027559; ENSMUSP00000027559; ENSMUSG00000026321

Database of genes from NCBI RefSeq genomes

More...GeneIDi		21934

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:21934

UCSC genome browser

More...UCSCi		uc007cgp.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF019046 mRNA Translation: AAB86810.1
BC019185 mRNA Translation: AAH19185.1
CCDSiCCDS15207.1
RefSeqiNP_033425.3, NM_009399.3

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3ME2X-ray2.80R26-210[»]
3ME4X-ray2.01A/B26-210[»]
3QBQX-ray2.50B/D32-201[»]
4GIQX-ray2.70R31-198[»]
5BNQX-ray2.80R26-210[»]
SMRiO35305
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi204246, 4 interactors
DIPiDIP-48710N
ELMiO35305
IntActiO35305, 11 interactors
MINTiO35305
STRINGi10090.ENSMUSP00000027559

PTM databases

GlyGeniO35305, 2 sites
iPTMnetiO35305
PhosphoSitePlusiO35305

Proteomic databases

MaxQBiO35305
PaxDbiO35305
PeptideAtlasiO35305
PRIDEiO35305
ProteomicsDBi260632

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		4165, 788 antibodies

Genome annotation databases

EnsembliENSMUST00000027559; ENSMUSP00000027559; ENSMUSG00000026321
GeneIDi21934
KEGGimmu:21934
UCSCiuc007cgp.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		8792
MGIiMGI:1314891, Tnfrsf11a

Phylogenomic databases

eggNOGiENOG502RWJI, Eukaryota
GeneTreeiENSGT00940000161211
HOGENOMiCLU_026571_0_0_1
InParanoidiO35305
OMAiFRGWITC
OrthoDBi1038336at2759
PhylomeDBiO35305
TreeFamiTF331157

Enzyme and pathway databases

ReactomeiR-MMU-5668541, TNFR2 non-canonical NF-kB pathway
R-MMU-5676594, TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		21934, 1 hit in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Tnfrsf11a, mouse
EvolutionaryTraceiO35305

Protein Ontology

More...PROi		PR:O35305
RNActiO35305, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000026321, Expressed in submandibular gland and 136 other tissues
GenevisibleiO35305, MM

Family and domain databases

CDDicd13411, TNFRSF11A, 1 hit
InterProiView protein in InterPro
IPR041648, RANK_CRD_2
IPR001368, TNFR/NGFR_Cys_rich_reg
IPR022323, TNFR_11
IPR022361, TNFR_11A
IPR034040, TNFRSF11A_N
PfamiView protein in Pfam
PF18278, RANK_CRD_2, 1 hit
PF00020, TNFR_c6, 1 hit
PRINTSiPR01961, TNFACTORR11
PR01974, TNFACTORR11A
SMARTiView protein in SMART
SM00208, TNFR, 4 hits
PROSITEiView protein in PROSITE
PS00652, TNFR_NGFR_1, 1 hit
PS50050, TNFR_NGFR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTNR11_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O35305
Secondary accession number(s): Q8VCT7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: January 1, 1998
Last modified: April 7, 2021
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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