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UniProtKB - O35114 (SCRB2_MOUSE)

Entry version 144 (02 Dec 2020)
Sequence version 3 (23 Jan 2007)
Previous versions | rss
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Protein

Lysosome membrane protein 2

Gene

Scarb2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.2 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-8856825, Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828, Clathrin-mediated endocytosis

Protein family/group databases

Transport Classification Database

More...TCDBi		9.B.39.1.9, the long chain fatty acid translocase (lcfat) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lysosome membrane protein 2
Alternative name(s):
85 kDa lysosomal membrane sialoglycoprotein
Short name:
LGP85
Lysosome membrane protein II
Short name:
LIMP II
Scavenger receptor class B member 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Scarb2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1196458, Scarb2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 4CytoplasmicSequence analysis4
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei5 – 27HelicalSequence analysisAdd BLAST23
Topological domaini28 – 433LumenalSequence analysisAdd BLAST406
Transmembranei434 – 459HelicalSequence analysisAdd BLAST26
Topological domaini460 – 478CytoplasmicSequence analysisAdd BLAST19

Keywords - Cellular componenti

Lysosome, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi45N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi68N → Q: Loss of glycosylation site. Causes retention in the endoplasmic reticulum and abolishes normal location in lysosomes. 1 Publication1
Mutagenesisi105N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi122N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi155L → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi156I → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi159M → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi160L → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi162A → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi163Y → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi166K → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi184I → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi187L → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi191F → D: Abolishes interaction with GBA. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi206N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi224N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi249N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi304N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi325N → Q: Loss of glycosylation site. Causes retention in the endoplasmic reticulum and abolishes normal location in lysosomes. 1 Publication1
Mutagenesisi400D → K: Slightly increased GBA binding. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi412N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1
Mutagenesisi430N → Q: Loss of glycosylation site. No effect on normal location in lysosomes. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001441561 – 478Lysosome membrane protein 2Add BLAST478

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi45N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi68N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi105N-linked (GlcNAc...) asparagine1 Publication1
Glycosylationi122N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi206N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi224N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi249N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi274 ↔ 329By similarity
Glycosylationi304N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi312 ↔ 318By similarity
Glycosylationi325N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi412N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi430N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Acylated by palmitic acid group(s).By similarity
Heavily glycosylated.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O35114

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		O35114

MaxQB - The MaxQuant DataBase

More...MaxQBi		O35114

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O35114

PeptideAtlas

More...PeptideAtlasi		O35114

PRoteomics IDEntifications database

More...PRIDEi		O35114

PTM databases

GlyConnect protein glycosylation platform

More...GlyConnecti		2497, 9 N-Linked glycans (2 sites)

GlyGen: Computational and Informatics Resources for Glycoscience

More...GlyGeni		O35114, 11 sites

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O35114

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O35114

SwissPalm database of S-palmitoylation events

More...SwissPalmi		O35114

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in the extracts of brain, heart, lung, liver and kidney.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000029426, Expressed in urinary bladder urothelium and 311 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O35114, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with GBA.

2 Publications

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		O35114, 6 interactors

Molecular INTeraction database

More...MINTi		O35114

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000031377

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O35114, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O35114

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni155 – 191Important for interaction with GBAAdd BLAST37

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CD36 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3776, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000153372

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_019853_3_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O35114

Identification of Orthologs from Complete Genome Data

More...OMAi		RCCFYAV

Database of Orthologous Groups

More...OrthoDBi		1106566at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O35114

TreeFam database of animal gene trees

More...TreeFami		TF317925

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR002159, CD36_fam
IPR005429, LimpII

The PANTHER Classification System

More...PANTHERi		PTHR11923, PTHR11923, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01130, CD36, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR01609, CD36FAMILY
PR01611, LIMPII

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O35114-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRCCFYTAG TLSLLLLVTS VTLLVARVFQ KAVDQTIEKN MVLQNGTKVF 
        60         70         80         90        100
NSWEKPPLPV YIQFYFFNVT NPEEILQGEI PLLEEVGPYT YRELRNKANI 
       110        120        130        140        150
QFGENGTTIS AVTNKAYVFE RNQSVGDPNV DLIRTINIPL LTVVDLAQLT 
       160        170        180        190        200
LLRELIEAML KAYQQKLFVI HTVHELLWGY KDEILSLVHI FKPDVSPNFG 
       210        220        230        240        250
LFYERNGTND GEYVFLTGED NYLNFSKIVE WNGKTSLDWW TTDTCNMING 
       260        270        280        290        300
TDGDSFHPLI SKDEVLYLFP SDLCRSVHIT FSSFENVEGL PAFRYKVPAE 
       310        320        330        340        350
ILANTSENAG FCIPEGNCMD SGVLNISICK NGAPIIMSFP HFYQADEKFV 
       360        370        380        390        400
SAIKGMHPNK EEHESFVDIN PLTGIILRGA KRFQINTYVR KLDDFVETGD 
       410        420        430        440        450
IRTMVFPVMY LNESVLIDKE TANQLKSVIN TTLVVTNIPY IIMALGVFFG 
       460        470 
LVFTWLACRG QGSMDEGTAD ERAPLIRT
Length:478
Mass (Da):54,044
Last modified:January 23, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i55724B77855470DF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB008553 mRNA Translation: BAA23372.1
AK011123 mRNA Translation: BAB27416.1
AK083038 mRNA Translation: BAC38740.1
AK144235 mRNA Translation: BAE25789.1
BC029073 mRNA Translation: AAH29073.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS19431.1

Protein sequence database of the Protein Information Resource

More...PIRi		JC5670

NCBI Reference Sequences

More...RefSeqi		NP_031670.1, NM_007644.4

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000031377; ENSMUSP00000031377; ENSMUSG00000029426

Database of genes from NCBI RefSeq genomes

More...GeneIDi		12492

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:12492

UCSC genome browser

More...UCSCi		uc008ydm.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB008553 mRNA Translation: BAA23372.1
AK011123 mRNA Translation: BAB27416.1
AK083038 mRNA Translation: BAC38740.1
AK144235 mRNA Translation: BAE25789.1
BC029073 mRNA Translation: AAH29073.1
CCDSiCCDS19431.1
PIRiJC5670
RefSeqiNP_031670.1, NM_007644.4

3D structure databases

SMRiO35114
ModBaseiSearch...

Protein-protein interaction databases

IntActiO35114, 6 interactors
MINTiO35114
STRINGi10090.ENSMUSP00000031377

Protein family/group databases

TCDBi9.B.39.1.9, the long chain fatty acid translocase (lcfat) family

PTM databases

GlyConnecti2497, 9 N-Linked glycans (2 sites)
GlyGeniO35114, 11 sites
iPTMnetiO35114
PhosphoSitePlusiO35114
SwissPalmiO35114

Proteomic databases

EPDiO35114
jPOSTiO35114
MaxQBiO35114
PaxDbiO35114
PeptideAtlasiO35114
PRIDEiO35114

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		3014, 386 antibodies

Genome annotation databases

EnsembliENSMUST00000031377; ENSMUSP00000031377; ENSMUSG00000029426
GeneIDi12492
KEGGimmu:12492
UCSCiuc008ydm.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		950
MGIiMGI:1196458, Scarb2

Phylogenomic databases

eggNOGiKOG3776, Eukaryota
GeneTreeiENSGT00940000153372
HOGENOMiCLU_019853_3_0_1
InParanoidiO35114
OMAiRCCFYAV
OrthoDBi1106566at2759
PhylomeDBiO35114
TreeFamiTF317925

Enzyme and pathway databases

ReactomeiR-MMU-8856825, Cargo recognition for clathrin-mediated endocytosis
R-MMU-8856828, Clathrin-mediated endocytosis

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		12492, 1 hit in 17 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Scarb2, mouse

Protein Ontology

More...PROi		PR:O35114
RNActiO35114, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000029426, Expressed in urinary bladder urothelium and 311 other tissues
GenevisibleiO35114, MM

Family and domain databases

InterProiView protein in InterPro
IPR002159, CD36_fam
IPR005429, LimpII
PANTHERiPTHR11923, PTHR11923, 1 hit
PfamiView protein in Pfam
PF01130, CD36, 1 hit
PRINTSiPR01609, CD36FAMILY
PR01611, LIMPII

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSCRB2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O35114
Secondary accession number(s): Q3UNF8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: January 23, 2007
Last modified: December 2, 2020
This is version 144 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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