We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - O34824 (GLMM_BACSU)
Protein
Phosphoglucosamine mutase
Gene
glmM
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity).
Glucosamine-1-phosphate is used for cell wall biosynthesis (Probable).
UniRule annotation1 PublicationCatalytic activityi
- EC:5.4.2.10UniRule annotation
Cofactori
Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 100 | Phosphoserine intermediate | 1 | |
Metal bindingi | 100 | Magnesium; via phosphate groupUniRule annotation | 1 | |
Metal bindingi | 240 | MagnesiumUniRule annotation | 1 | |
Metal bindingi | 242 | MagnesiumUniRule annotation | 1 | |
Metal bindingi | 244 | MagnesiumUniRule annotation | 1 |
GO - Molecular functioni
- magnesium ion binding Source: UniProtKB-UniRule
- phosphoglucosamine mutase activity Source: GO_Central
- phosphomannomutase activity Source: GO_Central
GO - Biological processi
- carbohydrate metabolic process Source: InterPro
- peptidoglycan biosynthetic process Source: GO_Central
- UDP-N-acetylglucosamine biosynthetic process Source: GO_Central
Keywordsi
Molecular function | Isomerase |
Ligand | Magnesium, Metal-binding |
Enzyme and pathway databases
BioCyci | BSUB:BSU01770-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:glmMUniRule annotation Synonyms:ybbT Ordered Locus Names:BSU01770 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000147846 | 1 – 448 | Phosphoglucosamine mutaseAdd BLAST | 448 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 100 | PhosphoserineUniRule annotation | 1 |
Post-translational modificationi
Activated by phosphorylation.UniRule annotation
Keywords - PTMi
PhosphoproteinProteomic databases
jPOSTi | O34824 |
PaxDbi | O34824 |
PRIDEi | O34824 |
Expressioni
Inductioni
Constitutively expressed, part of the cdaA-cdaR-glmM-glmS operon (PubMed:23192352).1 Publication
Interactioni
Subunit structurei
Homodimer, may form a complex with CdaA.
1 PublicationProtein-protein interaction databases
IntActi | O34824, 1 interactor |
MINTi | O34824 |
STRINGi | 224308.BSU01770 |
Family & Domainsi
Sequence similaritiesi
Belongs to the phosphohexose mutase family.UniRule annotation
Phylogenomic databases
eggNOGi | COG1109, Bacteria |
InParanoidi | O34824 |
OMAi | MFGEEYT |
PhylomeDBi | O34824 |
Family and domain databases
CDDi | cd05802, GlmM, 1 hit |
HAMAPi | MF_01554_B, GlmM_B, 1 hit |
InterProi | View protein in InterPro IPR005844, A-D-PHexomutase_a/b/a-I IPR016055, A-D-PHexomutase_a/b/a-I/II/III IPR005845, A-D-PHexomutase_a/b/a-II IPR005846, A-D-PHexomutase_a/b/a-III IPR005843, A-D-PHexomutase_C IPR036900, A-D-PHexomutase_C_sf IPR016066, A-D-PHexomutase_CS IPR005841, Alpha-D-phosphohexomutase_SF IPR006352, GlmM_bact |
Pfami | View protein in Pfam PF02878, PGM_PMM_I, 1 hit PF02879, PGM_PMM_II, 1 hit PF02880, PGM_PMM_III, 1 hit PF00408, PGM_PMM_IV, 1 hit |
PRINTSi | PR00509, PGMPMM |
SUPFAMi | SSF53738, SSF53738, 3 hits SSF55957, SSF55957, 1 hit |
TIGRFAMsi | TIGR01455, glmM, 1 hit |
PROSITEi | View protein in PROSITE PS00710, PGM_PMM, 1 hit |
i Sequence
Sequence statusi: Complete.
O34824-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKYFGTDGV RGVANSELTP ELAFKVGRFG GYVLTKDKQR PKVLIGRDTR
60 70 80 90 100
ISGHMLEGAL VAGLLSIGAE VMRLGVISTP GVSYLTKAMD AEAGVMISAS
110 120 130 140 150
HNPVQDNGIK FFGGDGFKLS DEQEAEIERL MDEPEDKLPR PVGADLGLVN
160 170 180 190 200
DYFEGGQKYL QFLKQTADED FTGIHVALDC ANGATSSLAT HLFADLDADV
210 220 230 240 250
STMGTSPNGL NINDGVGSTH PEALSAFVKE KNADLGLAFD GDGDRLIAVD
260 270 280 290 300
EKGNIVDGDQ IMYICSKHLK SEGRLKDDTV VSTVMSNLGF YKALEKEGIK
310 320 330 340 350
SVQTAVGDRY VVEAMKKDGY NVGGEQSGHL IFLDYNTTGD GLLSAIMLMN
360 370 380 390 400
TLKATGKPLS ELAAEMQKFP QLLVNVRVTD KYKVEENEKV KAVISEVEKE
410 420 430 440
MNGDGRILVR PSGTEPLVRV MAEAKTKELC DEYVNRIVEV VRSEMGLE
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 7 | T → K in BAA33070 (Ref. 1) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB006424 Genomic DNA Translation: BAA33070.1 AL009126 Genomic DNA Translation: CAB11953.1 |
PIRi | B69745 |
RefSeqi | NP_388058.1, NC_000964.3 WP_003234946.1, NZ_JNCM01000030.1 |
Genome annotation databases
EnsemblBacteriai | CAB11953; CAB11953; BSU_01770 |
GeneIDi | 938632 |
KEGGi | bsu:BSU01770 |
PATRICi | fig|224308.179.peg.183 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB006424 Genomic DNA Translation: BAA33070.1 AL009126 Genomic DNA Translation: CAB11953.1 |
PIRi | B69745 |
RefSeqi | NP_388058.1, NC_000964.3 WP_003234946.1, NZ_JNCM01000030.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
7OJR | X-ray | 3.05 | A | 1-448 | [»] | |
7OJS | X-ray | 4.20 | A/B/C/F/G/J | 1-369 | [»] | |
7OLH | X-ray | 3.65 | A/B/C/D/E/F | 1-448 | [»] | |
7OML | X-ray | 2.90 | A | 1-448 | [»] | |
SASBDBi | O34824 | |||||
SMRi | O34824 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | O34824, 1 interactor |
MINTi | O34824 |
STRINGi | 224308.BSU01770 |
Proteomic databases
jPOSTi | O34824 |
PaxDbi | O34824 |
PRIDEi | O34824 |
Protocols and materials databases
DNASUi | 938632 |
Genome annotation databases
EnsemblBacteriai | CAB11953; CAB11953; BSU_01770 |
GeneIDi | 938632 |
KEGGi | bsu:BSU01770 |
PATRICi | fig|224308.179.peg.183 |
Phylogenomic databases
eggNOGi | COG1109, Bacteria |
InParanoidi | O34824 |
OMAi | MFGEEYT |
PhylomeDBi | O34824 |
Enzyme and pathway databases
BioCyci | BSUB:BSU01770-MONOMER |
Family and domain databases
CDDi | cd05802, GlmM, 1 hit |
HAMAPi | MF_01554_B, GlmM_B, 1 hit |
InterProi | View protein in InterPro IPR005844, A-D-PHexomutase_a/b/a-I IPR016055, A-D-PHexomutase_a/b/a-I/II/III IPR005845, A-D-PHexomutase_a/b/a-II IPR005846, A-D-PHexomutase_a/b/a-III IPR005843, A-D-PHexomutase_C IPR036900, A-D-PHexomutase_C_sf IPR016066, A-D-PHexomutase_CS IPR005841, Alpha-D-phosphohexomutase_SF IPR006352, GlmM_bact |
Pfami | View protein in Pfam PF02878, PGM_PMM_I, 1 hit PF02879, PGM_PMM_II, 1 hit PF02880, PGM_PMM_III, 1 hit PF00408, PGM_PMM_IV, 1 hit |
PRINTSi | PR00509, PGMPMM |
SUPFAMi | SSF53738, SSF53738, 3 hits SSF55957, SSF55957, 1 hit |
TIGRFAMsi | TIGR01455, glmM, 1 hit |
PROSITEi | View protein in PROSITE PS00710, PGM_PMM, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GLMM_BACSU | |
Accessioni | O34824Primary (citable) accession number: O34824 Secondary accession number(s): O87090 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 20, 2005 |
Last sequence update: | January 1, 1998 | |
Last modified: | February 23, 2022 | |
This is version 127 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families