UniProtKB - O34815 (YOAD_BACSU)
Protein
Putative 2-hydroxyacid dehydrogenase YoaD
Gene
yoaD
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 193 | NADSequence analysis | 1 | |
Active sitei | 251 | Sequence analysis | 1 | |
Binding sitei | 275 | NADSequence analysis | 1 | |
Active sitei | 280 | Sequence analysis | 1 | |
Active sitei | 300 | Proton donorSequence analysis | 1 |
GO - Molecular functioni
- NAD binding Source: InterPro
- phosphoglycerate dehydrogenase activity Source: GO_Central
GO - Biological processi
- cellular amino acid metabolic process Source: GO_Central
Keywordsi
Molecular function | Oxidoreductase |
Ligand | NAD |
Enzyme and pathway databases
BioCyci | BSUB:BSU18560-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:yoaD Ordered Locus Names:BSU18560 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000386538 | 1 – 344 | Putative 2-hydroxyacid dehydrogenase YoaDAdd BLAST | 344 |
Proteomic databases
PaxDbi | O34815 |
PRIDEi | O34815 |
Expressioni
Inductioni
Induced by sulfate, part of the yoaDCB operon.1 Publication
Structurei
3D structure databases
ProteinModelPortali | O34815 |
SMRi | O34815 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.Curated
Phylogenomic databases
eggNOGi | ENOG4108M3J Bacteria COG0111 LUCA |
HOGENOMi | HOG000136700 |
InParanoidi | O34815 |
KOi | K00058 |
OMAi | CRGMPSN |
PhylomeDBi | O34815 |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00670 D_2_HYDROXYACID_DH_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O34815-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKNTMKRMFC SMTVLVTAPY NEEGRKELEN LFGSVAYQSW KEQGRAYRED
60 70 80 90 100
ELIQLLKATN ATGLITELDQ VTDSVFASVP ELSFVGVCRG MPSNVDVAAA
110 120 130 140 150
SKRGIPVFYT PGRNAQAVAE MFIGNVISFL RHTSASNQWL KDGEWDSDYL
160 170 180 190 200
QAYVKFKGNE LTGKTVGMIG FGAVGQRIAK LLTAFDCKIK YYDPYIQDDH
210 220 230 240 250
PLYEKASLKT VFSDSDIVSV HLPRTEETLG LIDRQYFDLM KESAIFVNTS
260 270 280 290 300
RAVVVNREDL LFVLKEHKIS GAILDVFYHE PPEESDYELI SLPNVLATPH
310 320 330 340
LAGATFEVED HHVTILNKAL KKWKGEKTLN IQTMYNKDAL KTGG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF027868 Genomic DNA Translation: AAB84446.1 AL009126 Genomic DNA Translation: CAB13749.1 |
PIRi | F69895 |
RefSeqi | NP_389738.1, NC_000964.3 WP_009967372.1, NZ_JNCM01000036.1 |
Genome annotation databases
EnsemblBacteriai | CAB13749; CAB13749; BSU18560 |
GeneIDi | 940109 |
KEGGi | bsu:BSU18560 |
PATRICi | fig|224308.179.peg.2023 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF027868 Genomic DNA Translation: AAB84446.1 AL009126 Genomic DNA Translation: CAB13749.1 |
PIRi | F69895 |
RefSeqi | NP_389738.1, NC_000964.3 WP_009967372.1, NZ_JNCM01000036.1 |
3D structure databases
ProteinModelPortali | O34815 |
SMRi | O34815 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
STRINGi | 224308.Bsubs1_010100010221 |
Proteomic databases
PaxDbi | O34815 |
PRIDEi | O34815 |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
EnsemblBacteriai | CAB13749; CAB13749; BSU18560 |
GeneIDi | 940109 |
KEGGi | bsu:BSU18560 |
PATRICi | fig|224308.179.peg.2023 |
Phylogenomic databases
eggNOGi | ENOG4108M3J Bacteria COG0111 LUCA |
HOGENOMi | HOG000136700 |
InParanoidi | O34815 |
KOi | K00058 |
OMAi | CRGMPSN |
PhylomeDBi | O34815 |
Enzyme and pathway databases
BioCyci | BSUB:BSU18560-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00670 D_2_HYDROXYACID_DH_2, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | YOAD_BACSU | |
Accessioni | O34815Primary (citable) accession number: O34815 Secondary accession number(s): Q796G0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 13, 2009 |
Last sequence update: | January 1, 1998 | |
Last modified: | January 16, 2019 | |
This is version 115 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Bacillus subtilis
Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList