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UniProtKB - O34557 (RPE_BACSU)
Protein
Ribulose-phosphate 3-epimerase
Gene
rpe
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.
UniRule annotationCatalytic activityi
- EC:5.1.3.1UniRule annotation
Cofactori
a divalent metal cationUniRule annotationNote: Binds 1 divalent metal cation per subunit.UniRule annotation
: Carbohydrate degradation Pathwayi
This protein is involved in Carbohydrate degradation.UniRule annotationView all proteins of this organism that are known to be involved in Carbohydrate degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 7 | SubstrateUniRule annotation | 1 | |
Metal bindingi | 32 | Divalent metal cation; via tele nitrogenUniRule annotation | 1 | |
Active sitei | 34 | Proton acceptorUniRule annotation | 1 | |
Metal bindingi | 34 | Divalent metal cationUniRule annotation | 1 | |
Metal bindingi | 65 | Divalent metal cation; via pros nitrogenUniRule annotation | 1 | |
Binding sitei | 65 | SubstrateUniRule annotation | 1 | |
Active sitei | 175 | Proton donorUniRule annotation | 1 | |
Metal bindingi | 175 | Divalent metal cationUniRule annotation | 1 |
GO - Molecular functioni
- D-ribulose-phosphate 3-epimerase activity Source: GO_Central
- metal ion binding Source: GO_Central
GO - Biological processi
- cellular carbohydrate metabolic process Source: GO_Central
- pentose catabolic process Source: GO_Central
- pentose-phosphate shunt, non-oxidative branch Source: GO_Central
Keywordsi
Molecular function | Isomerase |
Biological process | Carbohydrate metabolism |
Ligand | Metal-binding |
Enzyme and pathway databases
BioCyci | BSUB:BSU15790-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:rpeUniRule annotation Synonyms:yloR Ordered Locus Names:BSU15790 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000171561 | 1 – 217 | Ribulose-phosphate 3-epimeraseAdd BLAST | 217 |
Proteomic databases
PaxDbi | O34557 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 141 – 144 | Substrate bindingUniRule annotation | 4 | |
Regioni | 175 – 177 | Substrate bindingUniRule annotation | 3 | |
Regioni | 197 – 198 | Substrate bindingUniRule annotation | 2 |
Sequence similaritiesi
Belongs to the ribulose-phosphate 3-epimerase family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0036, Bacteria |
InParanoidi | O34557 |
OMAi | WLQVDGG |
PhylomeDBi | O34557 |
Family and domain databases
CDDi | cd00429, RPE, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_02227, RPE, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR026019, Ribul_P_3_epim IPR000056, Ribul_P_3_epim-like IPR011060, RibuloseP-bd_barrel |
PANTHERi | PTHR11749, PTHR11749, 1 hit |
Pfami | View protein in Pfam PF00834, Ribul_P_3_epim, 1 hit |
PIRSFi | PIRSF001461, RPE, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
TIGRFAMsi | TIGR01163, rpe, 1 hit |
PROSITEi | View protein in PROSITE PS01085, RIBUL_P_3_EPIMER_1, 1 hit PS01086, RIBUL_P_3_EPIMER_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O34557-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIKVAPSILS ADFAALGNEI KDVEKGGADC IHIDVMDGHF VPNITIGPLI
60 70 80 90 100
VEAVRPVTDL PLDVHLMIEE PDRYIPAFAK AGADILSVHA EACPHLHRTI
110 120 130 140 150
QLIKEQGVKA GVVLNPHTPV QVIEHVFDDL DLVLLMTVNP GFGGQKFIHS
160 170 180 190 200
VLPKIKEVKR MADEKGKKDL LIEVDGGVNK ETAPLVIEAG ANLLVAGSAV
210
YGQSDRKKAI SEIRGSK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y13937 Genomic DNA Translation: CAA74252.1 AL009126 Genomic DNA Translation: CAB13452.1 |
PIRi | B69879 |
RefSeqi | NP_389461.1, NC_000964.3 WP_003232058.1, NZ_JNCM01000035.1 |
Genome annotation databases
EnsemblBacteriai | CAB13452; CAB13452; BSU_15790 |
GeneIDi | 936393 |
KEGGi | bsu:BSU15790 |
PATRICi | fig|224308.179.peg.1719 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Y13937 Genomic DNA Translation: CAA74252.1 AL009126 Genomic DNA Translation: CAB13452.1 |
PIRi | B69879 |
RefSeqi | NP_389461.1, NC_000964.3 WP_003232058.1, NZ_JNCM01000035.1 |
3D structure databases
AlphaFoldDBi | O34557 |
SMRi | O34557 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU15790 |
Proteomic databases
PaxDbi | O34557 |
Genome annotation databases
EnsemblBacteriai | CAB13452; CAB13452; BSU_15790 |
GeneIDi | 936393 |
KEGGi | bsu:BSU15790 |
PATRICi | fig|224308.179.peg.1719 |
Phylogenomic databases
eggNOGi | COG0036, Bacteria |
InParanoidi | O34557 |
OMAi | WLQVDGG |
PhylomeDBi | O34557 |
Enzyme and pathway databases
BioCyci | BSUB:BSU15790-MONOMER |
Family and domain databases
CDDi | cd00429, RPE, 1 hit |
Gene3Di | 3.20.20.70, 1 hit |
HAMAPi | MF_02227, RPE, 1 hit |
InterProi | View protein in InterPro IPR013785, Aldolase_TIM IPR026019, Ribul_P_3_epim IPR000056, Ribul_P_3_epim-like IPR011060, RibuloseP-bd_barrel |
PANTHERi | PTHR11749, PTHR11749, 1 hit |
Pfami | View protein in Pfam PF00834, Ribul_P_3_epim, 1 hit |
PIRSFi | PIRSF001461, RPE, 1 hit |
SUPFAMi | SSF51366, SSF51366, 1 hit |
TIGRFAMsi | TIGR01163, rpe, 1 hit |
PROSITEi | View protein in PROSITE PS01085, RIBUL_P_3_EPIMER_1, 1 hit PS01086, RIBUL_P_3_EPIMER_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RPE_BACSU | |
Accessioni | O34557Primary (citable) accession number: O34557 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | January 1, 1998 | |
Last modified: | May 25, 2022 | |
This is version 123 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families