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Entry version 105 (16 Oct 2019)
Sequence version 1 (01 Jan 1998)
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Protein

Uncharacterized sodium-dependent transporter YocS

Gene

yocS

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processIon transport, Sodium transport, Symport, Transport
LigandSodium

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU19350-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Uncharacterized sodium-dependent transporter YocS
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yocS
Ordered Locus Names:BSU19350
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 6ExtracellularSequence analysis6
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 29HelicalSequence analysisAdd BLAST23
Topological domaini30 – 34CytoplasmicSequence analysis5
Transmembranei35 – 57HelicalSequence analysisAdd BLAST23
Topological domaini58 – 69ExtracellularSequence analysisAdd BLAST12
Transmembranei70 – 92HelicalSequence analysisAdd BLAST23
Topological domaini93 – 97CytoplasmicSequence analysis5
Transmembranei98 – 120HelicalSequence analysisAdd BLAST23
Topological domaini121 – 129ExtracellularSequence analysis9
Transmembranei130 – 150HelicalSequence analysisAdd BLAST21
Topological domaini151 – 159CytoplasmicSequence analysis9
Transmembranei160 – 180HelicalSequence analysisAdd BLAST21
Topological domaini181 – 190ExtracellularSequence analysis10
Transmembranei191 – 211HelicalSequence analysisAdd BLAST21
Topological domaini212 – 221CytoplasmicSequence analysis10
Transmembranei222 – 242HelicalSequence analysisAdd BLAST21
Topological domaini243 – 267ExtracellularSequence analysisAdd BLAST25
Transmembranei268 – 288HelicalSequence analysisAdd BLAST21
Topological domaini289 – 321CytoplasmicSequence analysisAdd BLAST33

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003604211 – 321Uncharacterized sodium-dependent transporter YocSAdd BLAST321

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O34524

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
224308.BSU19350

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O34524

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105C09 Bacteria
COG0385 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000236200

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O34524

KEGG Orthology (KO)

More...
KOi
K03453

Identification of Orthologs from Complete Genome Data

More...
OMAi
KSIMFVM

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O34524

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1530.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002657 BilAc:Na_symport/Acr3
IPR004710 Bilac:Na_transpt
IPR038770 Na+/solute_symporter_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10361 PTHR10361, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01758 SBF, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00841 bass, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O34524-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDIIRKISHF AGQTFGIWVI VFAVLGFSFP SLFTWISSYI TIFLGIIMFG
60 70 80 90 100
MGLTLQADDF KELVRKPWQV IIGVIAQYTI MPLVAFGLAF GLHLPAEIAV
110 120 130 140 150
GVILVGCCPG GTASNVMTFL AKGNTALSVA VTTISTLLAP VVTPLLIMLF
160 170 180 190 200
AKEWLPVSPG SLFISILQAV LFPIIAGLIV KMFFRKQVAK AVHALPLVSV
210 220 230 240 250
IGIVAIVSAV VSGNRENLLQ SGLLIFSVVI LHNGIGYLLG FLCAKLLKMD
260 270 280 290 300
YPSQKAIAIE VGMQNSGLGA ALATAHFSPL SAVPSAIFSV WHNLSGSMLA
310 320
TYWSKKVKKK QAGSKSSNLS L
Length:321
Mass (Da):34,251
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0D9CCF6B36E84A96
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF027868 Genomic DNA Translation: AAB84443.1
AL009126 Genomic DNA Translation: CAB13827.1

Protein sequence database of the Protein Information Resource

More...
PIRi
E69902

NCBI Reference Sequences

More...
RefSeqi
NP_389817.1, NC_000964.3
WP_004399225.1, NZ_JNCM01000036.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB13827; CAB13827; BSU19350

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
939452

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU19350

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.2116

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF027868 Genomic DNA Translation: AAB84443.1
AL009126 Genomic DNA Translation: CAB13827.1
PIRiE69902
RefSeqiNP_389817.1, NC_000964.3
WP_004399225.1, NZ_JNCM01000036.1

3D structure databases

SMRiO34524
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU19350

Proteomic databases

PaxDbiO34524

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
939452

Genome annotation databases

EnsemblBacteriaiCAB13827; CAB13827; BSU19350
GeneIDi939452
KEGGibsu:BSU19350
PATRICifig|224308.179.peg.2116

Phylogenomic databases

eggNOGiENOG4105C09 Bacteria
COG0385 LUCA
HOGENOMiHOG000236200
InParanoidiO34524
KOiK03453
OMAiKSIMFVM
PhylomeDBiO34524

Enzyme and pathway databases

BioCyciBSUB:BSU19350-MONOMER

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR002657 BilAc:Na_symport/Acr3
IPR004710 Bilac:Na_transpt
IPR038770 Na+/solute_symporter_sf
PANTHERiPTHR10361 PTHR10361, 1 hit
PfamiView protein in Pfam
PF01758 SBF, 1 hit
TIGRFAMsiTIGR00841 bass, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYOCS_BACSU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O34524
Secondary accession number(s): Q796C1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: October 16, 2019
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
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