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UniProtKB - O34442 (MGTE_BACSU)
Protein
Magnesium transporter MgtE
Gene
mgtE
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Acts as a magnesium transporter.
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 96 | Magnesium 1By similarity | 1 | |
Metal bindingi | 216 | Magnesium 3By similarity | 1 | |
Metal bindingi | 218 | Magnesium 4By similarity | 1 | |
Metal bindingi | 228 | Magnesium 5By similarity | 1 | |
Metal bindingi | 249 | Magnesium 1By similarity | 1 | |
Metal bindingi | 257 | Magnesium 3By similarity | 1 | |
Metal bindingi | 260 | Magnesium 3By similarity | 1 | |
Metal bindingi | 261 | Magnesium 4By similarity | 1 | |
Metal bindingi | 419 | Magnesium 4By similarity | 1 | |
Metal bindingi | 433 | Magnesium 6By similarity | 1 |
GO - Molecular functioni
- magnesium ion transmembrane transporter activity Source: InterPro
- metal ion binding Source: UniProtKB-KW
Keywordsi
Biological process | Transport |
Ligand | Magnesium, Metal-binding |
Enzyme and pathway databases
BioCyci | BSUB:BSU13300-MONOMER |
Protein family/group databases
TCDBi | 1.A.26.1.3, the mg(2+) transporter-e (mgte) family |
Names & Taxonomyi
Protein namesi | Recommended name: Magnesium transporter MgtE |
Gene namesi | Name:mgtE Synonyms:ykoK Ordered Locus Names:BSU13300 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane By similarity; Multi-pass membrane protein By similarity
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 277 | CytoplasmicBy similarityAdd BLAST | 277 | |
Transmembranei | 278 – 305 | Helical; Name=1By similarityAdd BLAST | 28 | |
Intramembranei | 306 – 320 | By similarityAdd BLAST | 15 | |
Transmembranei | 321 – 344 | Helical; Name=2By similarityAdd BLAST | 24 | |
Topological domaini | 345 – 351 | CytoplasmicBy similarity | 7 | |
Transmembranei | 352 – 382 | Helical; Name=3By similarityAdd BLAST | 31 | |
Intramembranei | 383 – 386 | By similarity | 4 | |
Transmembranei | 387 – 415 | Helical; Name=4By similarityAdd BLAST | 29 | |
Intramembranei | 416 – 425 | By similarity | 10 | |
Transmembranei | 426 – 448 | Helical; Name=5By similarityAdd BLAST | 23 | |
Topological domaini | 449 – 451 | PeriplasmicBy similarity | 3 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000363887 | 1 – 451 | Magnesium transporter MgtEAdd BLAST | 451 |
Proteomic databases
PaxDbi | O34442 |
PRIDEi | O34442 |
Interactioni
Subunit structurei
Homodimer.
By similarityProtein-protein interaction databases
STRINGi | 224308.BSU13300 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 140 – 203 | CBS 1PROSITE-ProRule annotationAdd BLAST | 64 | |
Domaini | 204 – 260 | CBS 2PROSITE-ProRule annotationAdd BLAST | 57 |
Sequence similaritiesi
Belongs to the SLC41A transporter family.Curated
Keywords - Domaini
CBS domain, Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2239, Bacteria |
InParanoidi | O34442 |
OMAi | TMTVAVR |
PhylomeDBi | O34442 |
Family and domain databases
Gene3Di | 1.10.357.20, 1 hit 1.25.60.10, 1 hit |
InterProi | View protein in InterPro IPR000644, CBS_dom IPR006668, Mg_transptr_MgtE_intracell_dom IPR038076, MgtE_N_sf IPR006669, MgtE_transporter IPR006667, SLC41_membr_dom IPR036739, SLC41_membr_dom_sf |
PANTHERi | PTHR43773, PTHR43773, 1 hit |
Pfami | View protein in Pfam PF00571, CBS, 2 hits PF01769, MgtE, 1 hit PF03448, MgtE_N, 1 hit |
SMARTi | View protein in SMART SM00116, CBS, 2 hits SM00924, MgtE_N, 1 hit |
SUPFAMi | SSF161093, SSF161093, 1 hit |
TIGRFAMsi | TIGR00400, mgtE, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 2 hits |
i Sequence
Sequence statusi: Complete.
O34442-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVQNMTYDEL ILRIIILLRD GKIRDFRSVI DELQPYDMAF IFKEMPEKHR
60 70 80 90 100
ARYLSYLTVD DITDMIGELE REFQLVVLNK VGKTKATLAM NKMDNDDLAQ
110 120 130 140 150
LLEEMDEELK EQLLSSMEAS ESKAVQLLMN YPADSAGRMM TNRYVWIPQH
160 170 180 190 200
YTVKDAVVKL KSFAEIAESI NYLYVINESK QLVGVLSYRD LILGEPEEKV
210 220 230 240 250
QDLMFTRVIS ADALQDQEEV ARLIERYDFL AIPVVEENNV LVGIVTVDDI
260 270 280 290 300
IDVVIREADE DYEKFAASGK DITFDTKAYV AAYRRLPWLI LLLFIGLISG
310 320 330 340 350
SIISYFEDAL KQVVALAFFM PMVSGMTGNT GTQSLAVVIR GLSKEEMNKK
360 370 380 390 400
TIVRLIFREF RTSIFIGAVC SVLIAIVSII WQGNALLGFV VASSLFLTLI
410 420 430 440 450
IGTMSGTIIP IILHKLKVDP AIASGPLITT LNDILSLLIY FGIATAFIHS
L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ002571 Genomic DNA Translation: CAA05608.1 AL009126 Genomic DNA Translation: CAB13187.1 |
PIRi | G69859 |
RefSeqi | NP_389213.1, NC_000964.3 WP_003232543.1, NZ_JNCM01000035.1 |
Genome annotation databases
EnsemblBacteriai | CAB13187; CAB13187; BSU_13300 |
GeneIDi | 936439 |
KEGGi | bsu:BSU13300 |
PATRICi | fig|224308.179.peg.1445 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ002571 Genomic DNA Translation: CAA05608.1 AL009126 Genomic DNA Translation: CAB13187.1 |
PIRi | G69859 |
RefSeqi | NP_389213.1, NC_000964.3 WP_003232543.1, NZ_JNCM01000035.1 |
3D structure databases
SMRi | O34442 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224308.BSU13300 |
Protein family/group databases
TCDBi | 1.A.26.1.3, the mg(2+) transporter-e (mgte) family |
Proteomic databases
PaxDbi | O34442 |
PRIDEi | O34442 |
Genome annotation databases
EnsemblBacteriai | CAB13187; CAB13187; BSU_13300 |
GeneIDi | 936439 |
KEGGi | bsu:BSU13300 |
PATRICi | fig|224308.179.peg.1445 |
Phylogenomic databases
eggNOGi | COG2239, Bacteria |
InParanoidi | O34442 |
OMAi | TMTVAVR |
PhylomeDBi | O34442 |
Enzyme and pathway databases
BioCyci | BSUB:BSU13300-MONOMER |
Family and domain databases
Gene3Di | 1.10.357.20, 1 hit 1.25.60.10, 1 hit |
InterProi | View protein in InterPro IPR000644, CBS_dom IPR006668, Mg_transptr_MgtE_intracell_dom IPR038076, MgtE_N_sf IPR006669, MgtE_transporter IPR006667, SLC41_membr_dom IPR036739, SLC41_membr_dom_sf |
PANTHERi | PTHR43773, PTHR43773, 1 hit |
Pfami | View protein in Pfam PF00571, CBS, 2 hits PF01769, MgtE, 1 hit PF03448, MgtE_N, 1 hit |
SMARTi | View protein in SMART SM00116, CBS, 2 hits SM00924, MgtE_N, 1 hit |
SUPFAMi | SSF161093, SSF161093, 1 hit |
TIGRFAMsi | TIGR00400, mgtE, 1 hit |
PROSITEi | View protein in PROSITE PS51371, CBS, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | MGTE_BACSU | |
Accessioni | O34442Primary (citable) accession number: O34442 Secondary accession number(s): Q796L4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 10, 2009 |
Last sequence update: | January 1, 1998 | |
Last modified: | September 29, 2021 | |
This is version 121 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families