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Protein

Altronate oxidoreductase

Gene

uxaB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

Member of the exu locus which is required for galacturonate utilization.

Catalytic activityi

D-altronate + NAD+ = D-tagaturonate + NADH.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 30NADUniRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciBSUB:BSU12380-MONOMER
UniPathwayiUPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Altronate oxidoreductaseUniRule annotation (EC:1.1.1.58UniRule annotation)
Alternative name(s):
Tagaturonate dehydrogenaseUniRule annotation
Tagaturonate reductaseUniRule annotation
Gene namesi
Name:uxaBUniRule annotation
Synonyms:yjmI
Ordered Locus Names:BSU12380
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001707391 – 480Altronate oxidoreductaseAdd BLAST480

Proteomic databases

PaxDbiO34354
PRIDEiO34354

Expressioni

Inductioni

Induced by galacturonate, repressed by glucose.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100006841

Structurei

3D structure databases

ProteinModelPortaliO34354
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the mannitol dehydrogenase family. UxaB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107QZW Bacteria
COG0246 LUCA
HOGENOMiHOG000029586
InParanoidiO34354
KOiK00041
OMAiVVIVRPI
PhylomeDBiO34354

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
HAMAPiMF_00670 Altron_oxidoreduct, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR023668 Altronate_OxRdtase
IPR000669 Mannitol_DH
IPR013118 Mannitol_DH_C
IPR013131 Mannitol_DH_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF01232 Mannitol_dh, 1 hit
PF08125 Mannitol_dh_C, 1 hit
PRINTSiPR00084 MTLDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 1 hit

Sequencei

Sequence statusi: Complete.

O34354-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKLNKNVYD HYTQYPEKIL QFGEGNFLRG FIDWQIDQLN QHTDFNGSVA
60 70 80 90 100
VVQPRGSEKI KRLNEQDGLY TLFLQGMKDG EAVNEHMIIN SISRGIDLFS
110 120 130 140 150
DYEAYKELAS SERLRFIISN TTEAGIVCDE KDRLEDRPQK TFPGKLTAFL
160 170 180 190 200
YFRYQAFKGD QTKGCVLIPC ELIENNGEKL RETVLHYAHL WKLEEGFTQW
210 220 230 240 250
IHEANTFCNS LVDRIVPGFP VDSIDEITAD LGYQDDLIVV GEQYYLWVIE
260 270 280 290 300
GPDWIGKELP FAAAGLHTKI VSDLTPYRTK KVRILNGAHT AMTPVALLYG
310 320 330 340 350
LKTVRDAVEH PEVGRFIREL IDDEILPVLK MEGLSQYADD VLNRFKNPYI
360 370 380 390 400
KHYLESIALN AISKFKTRNL PTLKEYAEQK GQLPERLVFS FSALLYFYHD
410 420 430 440 450
NETLQDDPAV LQFFKEVWCQ EDGDMLRIAS RVLGEQRLWG ADLNEIPKLT
460 470 480
DRVAVYLNHI HELGMQRALE QYCIQGGEVR
Length:480
Mass (Da):55,361
Last modified:January 1, 1998 - v1
Checksum:iDC7DBC8DA500F8D4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF015825 Genomic DNA Translation: AAC46334.1
AL009126 Genomic DNA Translation: CAB13095.1
PIRiC69853
RefSeqiNP_389120.1, NC_000964.3
WP_003245710.1, NZ_JNCM01000035.1

Genome annotation databases

EnsemblBacteriaiCAB13095; CAB13095; BSU12380
GeneIDi936468
KEGGibsu:BSU12380
PATRICifig|224308.179.peg.1339

Similar proteinsi

Entry informationi

Entry nameiUXAB_BACSU
AccessioniPrimary (citable) accession number: O34354
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2003
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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