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Entry version 110 (02 Jun 2021)
Sequence version 1 (01 Jan 1998)
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Protein

Putative phosphoenolpyruvate synthase

Gene

pps

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Might catalyze the phosphorylation of pyruvate to phosphoenolpyruvate.

Curated

Caution

Lacks almost all of the known catalytic and substrate-binding residues for this enzyme; hence it is annotated as putative.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei825Tele-phosphohistidine intermediateSequence analysis1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU18830-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative phosphoenolpyruvate synthase
Short name:
Putative PEP synthase
Alternative name(s):
Pyruvate, water dikinase
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pps
Ordered Locus Names:BSU18830
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003780891 – 866Putative phosphoenolpyruvate synthaseAdd BLAST866

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O34309

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
224308.BSU18830

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O34309

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni410 – 429DisorderedSequence analysisAdd BLAST20

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the PEP-utilizing enzyme family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0574, Bacteria
COG3848, Bacteria

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O34309

Identification of Orthologs from Complete Genome Data

More...
OMAi
WTRKIAA

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O34309

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.1490.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013815, ATP_grasp_subdomain_1
IPR008279, PEP-util_enz_mobile_dom
IPR036637, Phosphohistidine_dom_sf
IPR002192, PPDK_AMP/ATP-bd

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00391, PEP-utilizers, 1 hit
PF01326, PPDK_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52009, SSF52009, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O34309-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSLVLGLHE IEKTQLSLVG GKGLHLGELS KIQGIQVPEG FCVTTVGYQK
60 70 80 90 100
AIEQNETLQV LLDQLTMLKV EDRDQIGNIS RKIRQIIMEV DIPSDVVKAV
110 120 130 140 150
AQYLSQFGEE HAYAVRSSAT AEDLPHASFA GQQDTYLNIT GVDAILQHIS
160 170 180 190 200
KCWASLFTDR AVIYRMQNGF DHSQVYLSVI VQRMVFPQAS GILFTADPIT
210 220 230 240 250
SNRKVLSIDA GFGLGEALVS GLVSADCFKV QDGQIIDKRI ATKKMAIYGR
260 270 280 290 300
KEGGTETQQI DSDQQKAQTL TDEQILQLAR IGRQIEAHFG QPQDIEWCLA
310 320 330 340 350
RDTFYIVQSR PITTLFPIPE ASDQENHVYI SVGHQQMMTD PIKPLGLSFF
360 370 380 390 400
LLTTVAPMRK AGGRLFVDVT HHLASPDSRE VFLKGMGQHD QLLKDALMTI
410 420 430 440 450
IKRRDFIKSI PNDKTAPNPS RGNADMPAQV ENDPTIVSDL IESSQTSIEE
460 470 480 490 500
LKQNIQTKSG SDLFRFILED IQELKKILFN PKSSVLIRTA MNASLWINEK
510 520 530 540 550
MNEWLGEKNA ADTLSQSVPH NITSEMGLAL LDVADVIRPY PEVIDYLQHV
560 570 580 590 600
KDDNFLDELA KFDGGSKTRD AIYDYLSKYG MRCTGEIDIT RTRWSEKPTT
610 620 630 640 650
LVPMILNNIK NFEPNVGHRK FEQGRQEALK KEQELLDRLK QLPDGEQKAK
660 670 680 690 700
ETKRAIDIIR NFSGFREYPK YGMVNRYFVY KQALLKEAEQ LIEAGVIHEK
710 720 730 740 750
EDIYYLTFEE LHEVVRTHKL DYQIISTRKD EYTLYEKLSP PRVITSDGEI
760 770 780 790 800
VTGEYKRENL PAGAIVGLPV SSGVIEGRAR VILNMEDADL EDGDILVTSF
810 820 830 840 850
TDPSWTPLFV SIKGLVTEVG GLMTHGAVIA REYGLPAVVG VENAAKLIKD
860
GQRIRVHGTE GYIEIF
Length:866
Mass (Da):97,192
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5C1D3BC30F074DEA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti267 – 272AQTLTD → GSNTELI in CAA84277 (PubMed:7704256).Curated6
Sequence conflicti625 – 645RQEAL…QLPDG → ATGSFEERTRVIRSIEAITG C in CAA84277 (PubMed:7704256).CuratedAdd BLAST21
Sequence conflicti850D → H in CAA84277 (PubMed:7704256).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF027868 Genomic DNA Translation: AAB84457.1
AL009126 Genomic DNA Translation: CAB13775.1
Z34519 Genomic DNA Translation: CAA84277.1

Protein sequence database of the Protein Information Resource

More...
PIRi
F69681

NCBI Reference Sequences

More...
RefSeqi
NP_389764.1, NC_000964.3
WP_003231379.1, NZ_JNCM01000036.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB13775; CAB13775; BSU_18830

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
939985

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU18830

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.2053

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF027868 Genomic DNA Translation: AAB84457.1
AL009126 Genomic DNA Translation: CAB13775.1
Z34519 Genomic DNA Translation: CAA84277.1
PIRiF69681
RefSeqiNP_389764.1, NC_000964.3
WP_003231379.1, NZ_JNCM01000036.1

3D structure databases

SMRiO34309
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU18830

Proteomic databases

PaxDbiO34309

Genome annotation databases

EnsemblBacteriaiCAB13775; CAB13775; BSU_18830
GeneIDi939985
KEGGibsu:BSU18830
PATRICifig|224308.179.peg.2053

Phylogenomic databases

eggNOGiCOG0574, Bacteria
COG3848, Bacteria
InParanoidiO34309
OMAiWTRKIAA
PhylomeDBiO34309

Enzyme and pathway databases

BioCyciBSUB:BSU18830-MONOMER

Family and domain databases

Gene3Di3.30.1490.20, 1 hit
InterProiView protein in InterPro
IPR013815, ATP_grasp_subdomain_1
IPR008279, PEP-util_enz_mobile_dom
IPR036637, Phosphohistidine_dom_sf
IPR002192, PPDK_AMP/ATP-bd
PfamiView protein in Pfam
PF00391, PEP-utilizers, 1 hit
PF01326, PPDK_N, 1 hit
SUPFAMiSSF52009, SSF52009, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPPS_BACSU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O34309
Secondary accession number(s): O69265, Q796E8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: January 1, 1998
Last modified: June 2, 2021
This is version 110 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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