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Protein

60 kDa chaperonin

Gene

groL

Organism
Bartonella quintana (strain Toulouse) (Rochalimaea quintana)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Heat shock protein 60
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation, mopA
Ordered Locus Names:BQ10750
OrganismiBartonella quintana (strain Toulouse) (Rochalimaea quintana)
Taxonomic identifieri283165 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
Proteomesi
  • UP000000597 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000632841 – 54760 kDa chaperoninAdd BLAST547

Proteomic databases

PRIDEiO33964

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi283165.BQ10750

Structurei

3D structure databases

ProteinModelPortaliO33964
SMRiO33964
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9 Bacteria
COG0459 LUCA
HOGENOMiHOG000076290
KOiK04077
OMAiTDTDKME
OrthoDBiPOG091H00E7

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

O33964-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAKEVKFGR EARERLLRGV DILANAVKVT LGPKGRNVVI DKSFGAPRIT
60 70 80 90 100
KDGVSVAKEI ELEDKFENMG AQMLREVASK TNDIAGDGTT TATVLGQAIV
110 120 130 140 150
QEGVKAVAAG MNPMDLKRGI DAAVEEVVGN LFKKAKKIQT SAEIAQVGTI
160 170 180 190 200
SANGAAEIGK MIADAMEKVG NEGVITVEEA KTAETELEVV EGMQFDRGYL
210 220 230 240 250
SPYFVTNADK MVADLDDPYI LIHEKKLSNL QSLLPVLEAV VQSGKPLLII
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKIAAVKAPG FGDRRKAMLE DIAILTSGQV
310 320 330 340 350
ISEDVGIKLE NVTLDMLGRA KKVNISKENT TIIDGAGKKA EINARVNQIK
360 370 380 390 400
VQIEETTSDY DREKLQERLA KLAGGVAVIR VGGATEVEVK EKKDRVDDAL
410 420 430 440 450
NATRAAVEEG IVAGGGTALL RAANALAIKG SNPDQEAGIN IVRRALQAPA
460 470 480 490 500
RQIATNAGEE AAIIVGKVLE NNADTFGYNT ATGQFGDLIA LGIVDPVKVV
510 520 530 540
RSALQNAASI ASLLITTEAM VAEVPKKDTP MPPMPGGGMG GMGGMDF
Length:547
Mass (Da):57,610
Last modified:January 1, 1998 - v1
Checksum:i8620CFC50BF2D6F4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78515 Genomic DNA Translation: AAB69095.1
BX897700 Genomic DNA Translation: CAF26542.1
RefSeqiWP_011179743.1, NC_005955.1

Genome annotation databases

EnsemblBacteriaiCAF26542; CAF26542; BQ10750
GeneIDi34145597
KEGGibqu:BQ10750

Similar proteinsi

Entry informationi

Entry nameiCH60_BARQU
AccessioniPrimary (citable) accession number: O33964
Secondary accession number(s): Q6FYV0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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