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Entry version 133 (02 Jun 2021)
Sequence version 1 (01 Jan 1998)
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Protein

Esterase EstA

Gene

estA

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Esterase whose enzymatic activity is required for rhamnolipid production, all kinds of cell motility (swimming, swarming, and twitching), and biofilm formation; the exact role of EstA in these processes is unclear. In vitro, has pronounced esterase activities towards p-nitrophenyl esters of short acyl chain length (C4-C6) and Tween detergents. Also shows relatively high activity towards beta-naphthyl butyrate, whereas its activities towards triacylglycerols and acyls-CoA are negligible.

2 Publications

Miscellaneous

Overexpression of EstA results in an increased production of rhamnolipids (PubMed:17631636). Rhamnolipid production is strongly influenced by the C/N ratio of the environment. At a C/N ratio of 83.2, a modified P.aeruginosa strain capable of overexpressing the estA gene can produce up to 3.9 times more rhamnolipids than the wild-type strain (PubMed:28837648).2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.<p><a href='/help/biophysicochemical_properties' target='_top'>More...</a></p>Kineticsi

  1. KM=0.7 mM for p-nitrophenyl butyrate1 Publication
  1. Vmax=220 µmol/min/mg enzyme with p-nitrophenyl butyrate as substrate1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei38NucleophileCurated1
Active sitei310Curated1
Active sitei313Curated1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase, Serine esterase

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PAER208964:G1FZ6-5227-MONOMER

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
3.1.1.1, 5087

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.B.12.5.9, the autotransporter-1 (at-1) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Esterase EstA (EC:3.1.1.12 Publications)
Alternative name(s):
Autotransporter esterase EstA
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:estA
Synonyms:papA
Ordered Locus Names:PA5112
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri208964 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002438 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

Organism-specific databases

Pseudomonas genome database

More...
PseudoCAPi
PA5112

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini25 – 397ExtracellularSequence analysisAdd BLAST373
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei398 – 408Beta strandedSequence analysisAdd BLAST11
Topological domaini409 – 410PeriplasmicSequence analysis2
Transmembranei411 – 421Beta strandedSequence analysisAdd BLAST11
Topological domaini422 – 437ExtracellularSequence analysisAdd BLAST16
Transmembranei438 – 447Beta strandedSequence analysis10
Topological domaini448 – 451PeriplasmicSequence analysis4
Transmembranei452 – 461Beta strandedSequence analysis10
Topological domaini462 – 488ExtracellularSequence analysisAdd BLAST27
Transmembranei489 – 500Beta strandedSequence analysisAdd BLAST12
Topological domaini501 – 507PeriplasmicSequence analysis7
Transmembranei508 – 518Beta strandedSequence analysisAdd BLAST11
Topological domaini519 – 547ExtracellularSequence analysisAdd BLAST29
Transmembranei548 – 558Beta strandedSequence analysisAdd BLAST11
Topological domaini559 – 561PeriplasmicSequence analysis3
Transmembranei562 – 571Beta strandedSequence analysis10
Topological domaini572 – 605ExtracellularSequence analysisAdd BLAST34
Transmembranei606 – 615Beta strandedSequence analysis10
Topological domaini616 – 618PeriplasmicSequence analysis3
Transmembranei619 – 628Beta strandedSequence analysis10
Topological domaini629 – 636ExtracellularSequence analysis8
Transmembranei637 – 646Beta strandedSequence analysis10

Keywords - Cellular componenti

Cell outer membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Strains lacking this gene produce only marginal amounts of extracellular rhamnolipids. They also show no swarming motility, and both other forms of surface motility, swimming and twitching, are completely absent in these mutant cells. Biofilm formation is also affected.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi38S → A: Loss of catalytic activity. Fails to complement the estA mutant phenotypes. 1 Publication1

Chemistry databases

Drug and drug target database

More...
DrugBanki
DB04233, (Hydroxyethyloxy)Tri(Ethyloxy)Octane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001784525 – 646Esterase EstAAdd BLAST622

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O33407

PRoteomics IDEntifications database

More...
PRIDEi
O33407

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1646
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O33407

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
O33407

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini366 – 646AutotransporterPROSITE-ProRule annotationAdd BLAST281

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains a C-terminal autotransporter domain that integrates into the outer membrane and enables the translocation of the catalytic N-terminal domain to the bacterial cell surface.1 Publication

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the 'GDSL' lipolytic enzyme family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_023098_5_0_6

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O33407

Identification of Orthologs from Complete Genome Data

More...
OMAi
GNYNWRK

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O33407

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.128.130, 1 hit
3.40.50.1110, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005546, Autotransporte_beta
IPR036709, Autotransporte_beta_dom_sf
IPR001087, GDSL
IPR017186, Lipase_autotranspt_EstA
IPR008265, Lipase_GDSL_AS
IPR036514, SGNH_hydro_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03797, Autotransporter, 1 hit
PF00657, Lipase_GDSL, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037375, Autotrns_EstA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00869, Autotransporter, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103515, SSF103515, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51208, AUTOTRANSPORTER, 1 hit
PS01098, LIPASE_GDSL_SER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

O33407-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIRMALKPLV AACLLASLST APQAAPSPYS TLVVFGDSLS DAGQFPDPAG
60 70 80 90 100
PAGSTSRFTN RVGPTYQNGS GEIFGPTAPM LLGNQLGIAP GDLAASTSPV
110 120 130 140 150
NAQQGIADGN NWAVGGYRTD QIYDSITAAN GSLIERDNTL LRSRDGYLVD
160 170 180 190 200
RARQGLGADP NALYYITGGG NDFLQGRILN DVQAQQAAGR LVDSVQALQQ
210 220 230 240 250
AGARYIVVWL LPDLGLTPAT FGGPLQPFAS QLSGTFNAEL TAQLSQAGAN
260 270 280 290 300
VIPLNIPLLL KEGMANPASF GLAADQNLIG TCFSGNGCTM NPTYGINGST
310 320 330 340 350
PDPSKLLFND SVHPTITGQR LIADYTYSLL SAPWELTLLP EMAHGTLRAY
360 370 380 390 400
QDELRSQWQA DWENWQNVGQ WRGFVGGGGQ RLDFDSQDSA ASGDGNGYNL
410 420 430 440 450
TLGGSYRIDE AWRAGVAAGF YRQKLEAGAK DSDYRMNSYM ASAFVQYQEN
460 470 480 490 500
RWWADAALTG GYLDYDDLKR KFALGGGERS EKGDTNGHLW AFSARLGYDI
510 520 530 540 550
AQQADSPWHL SPFVSADYAR VEVDGYSEKG ASATALDYDD QKRSSKRLGA
560 570 580 590 600
GLQGKYAFGS DTQLFAEYAH EREYEDDTQD LTMSLNSLPG NRFTLEGYTP
610 620 630 640
QDHLNRVSLG FSQKLAPELS LRGGYNWRKG EDDTQQSVSL ALSLDF
Length:646
Mass (Da):69,609
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAFF3CC4FFE25A191
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAC14200 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF005091 Genomic DNA Translation: AAB61674.1
AJ277638 Genomic DNA Translation: CAC14200.1 Different initiation.
AE004091 Genomic DNA Translation: AAG08497.1

Protein sequence database of the Protein Information Resource

More...
PIRi
G83006

NCBI Reference Sequences

More...
RefSeqi
NP_253799.1, NC_002516.2
WP_003115524.1, NZ_QZGE01000002.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAG08497; AAG08497; PA5112

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
878826

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pae:PA5112

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|208964.12.peg.5357

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF005091 Genomic DNA Translation: AAB61674.1
AJ277638 Genomic DNA Translation: CAC14200.1 Different initiation.
AE004091 Genomic DNA Translation: AAG08497.1
PIRiG83006
RefSeqiNP_253799.1, NC_002516.2
WP_003115524.1, NZ_QZGE01000002.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3KVNX-ray2.50A/X25-646[»]
SMRiO33407
ModBaseiSearch...
PDBe-KBiSearch...

Chemistry databases

DrugBankiDB04233, (Hydroxyethyloxy)Tri(Ethyloxy)Octane

Protein family/group databases

TCDBi1.B.12.5.9, the autotransporter-1 (at-1) family

Proteomic databases

PaxDbiO33407
PRIDEiO33407

Genome annotation databases

EnsemblBacteriaiAAG08497; AAG08497; PA5112
GeneIDi878826
KEGGipae:PA5112
PATRICifig|208964.12.peg.5357

Organism-specific databases

PseudoCAPiPA5112

Phylogenomic databases

HOGENOMiCLU_023098_5_0_6
InParanoidiO33407
OMAiGNYNWRK
PhylomeDBiO33407

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-5227-MONOMER
BRENDAi3.1.1.1, 5087

Miscellaneous databases

EvolutionaryTraceiO33407

Family and domain databases

Gene3Di2.40.128.130, 1 hit
3.40.50.1110, 1 hit
InterProiView protein in InterPro
IPR005546, Autotransporte_beta
IPR036709, Autotransporte_beta_dom_sf
IPR001087, GDSL
IPR017186, Lipase_autotranspt_EstA
IPR008265, Lipase_GDSL_AS
IPR036514, SGNH_hydro_sf
PfamiView protein in Pfam
PF03797, Autotransporter, 1 hit
PF00657, Lipase_GDSL, 1 hit
PIRSFiPIRSF037375, Autotrns_EstA, 1 hit
SMARTiView protein in SMART
SM00869, Autotransporter, 1 hit
SUPFAMiSSF103515, SSF103515, 1 hit
PROSITEiView protein in PROSITE
PS51208, AUTOTRANSPORTER, 1 hit
PS01098, LIPASE_GDSL_SER, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiESTA_PSEAE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O33407
Secondary accession number(s): Q7DC45, Q9F3Y2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 21, 2004
Last sequence update: January 1, 1998
Last modified: June 2, 2021
This is version 133 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
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