Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 108 (07 Apr 2021)
Sequence version 1 (01 Jan 1998)
Previous versions | rss
Add a publicationFeedback
Protein

Single-stranded-DNA-specific exonuclease RecJ

Gene

recJ

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative single-stranded-DNA-specific exonuclease (By similarity). RecA thread formation during DNA double-strand break repair requires RecJ or AadAB.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position and type of each DNA-binding domain present within the protein.<p><a href='/help/dna_bind' target='_top'>More...</a></p>DNA bindingi485 – 563OBAdd BLAST79

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding, Exonuclease, Hydrolase, Nuclease

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU27620-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Single-stranded-DNA-specific exonuclease RecJ (EC:3.1.-.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:recJ
Synonyms:yrvE
Ordered Locus Names:BSU27620
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Cells lacking this gene show only slightly increased sensitivity to DNA-damaging agents. However, cells lacking RecJ and with a mutated AadAB enzyme were extremely sensitive to these agents, as sensitive as recA deletion strains. The doubly mutated strain shows 10-fold impaired growth in the absence of these agents.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003608061 – 786Single-stranded-DNA-specific exonuclease RecJAdd BLAST786

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O32044

PRoteomics IDEntifications database

More...
PRIDEi
O32044

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
224308.BSU27620

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O32044

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili300 – 332Sequence analysisAdd BLAST33

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RecJ family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0608, Bacteria
COG4199, Bacteria

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O32044

Identification of Orthologs from Complete Genome Data

More...
OMAi
FIICDHH

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O32044

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001667, DDH_dom
IPR038763, DHH_sf
IPR003156, DHHA1_dom
IPR004610, RecJ
IPR018779, RecJ_C
IPR041122, RecJ_OB

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01368, DHH, 1 hit
PF02272, DHHA1, 1 hit
PF17768, RecJ_OB, 1 hit
PF10141, ssDNA-exonuc_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF64182, SSF64182, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00644, recJ, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O32044-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLASKMRWEI QRPDQDKVKS LTEQLHITPL VASLLVKRGF DTAESARLFL
60 70 80 90 100
HTKDADFYDP FEMKGMKEAA DRIKQAISQQ EKIMIYGDYD ADGVTSTSVM
110 120 130 140 150
LHTLQKLSAQ VDFYIPDRFK EGYGPNEQAF RSIKERGFSL IITVDTGIAA
160 170 180 190 200
VHEAKVAKEL GLDVIITDHH EPGPELPDVR AIVHPKQPGC TYPFKELAGV
210 220 230 240 250
GVAFKLAHAL LGELPDELLD LAAIGTIADL VPLHDENRLI ATLGLERLRR
260 270 280 290 300
TNRLGLKELI KLSGGDIGEA NEETVGFQLA PRLNAVGRIE QADPAVHLLM
310 320 330 340 350
SEDSFEAEEL AAEIDQLNKE RQKMVSKMTD EAIEMVEQQG LDQTAIVVAK
360 370 380 390 400
AGWNPGVVGI VASKLVDRFY RPAIVLGIDE EKGIAKGSAR SIRGFNLFES
410 420 430 440 450
LSECRDILPH FGGHPMAAGM TLKAEDVPDL RSRLNEIADN TLTEEDFIPV
460 470 480 490 500
QEVDLVCGVE DITVESIAEM NMLSPFGMLN PKPHVLVENA VLEDVRKIGA
510 520 530 540 550
NKTHVKMTIR NESSQLDCVG FNKGELQEGI VPGSRISIVG EMSINEWNNR
560 570 580 590 600
KKPQLMIKDA AVSEWQLFDL RGKRTWEDTV SALPSAKRAI VSFKEDSTTL
610 620 630 640 650
LQTEDLRREV HVISSKDQAK AFDLDGAYIV LLDPPPSLDM LARLLEGKAP
660 670 680 690 700
ERIYFIFLNH EDHFLSTFPA RDHFKWYYAF LLKRGAFDVK KHGSELAKHK
710 720 730 740 750
GWSVETINFM TKVFFDLGFV KIENGVLSVV SGAKKRDLTD SQTYQAKQQL
760 770 780
MELDQKLNYS SAEELKEWLN KLMKQDSEAY ESTRRT
Length:786
Mass (Da):88,023
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i49749992D35B1229
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL009126 Genomic DNA Translation: CAB14721.1

Protein sequence database of the Protein Information Resource

More...
PIRi
H69980

NCBI Reference Sequences

More...
RefSeqi
NP_390640.1, NC_000964.3
WP_003246110.1, NZ_JNCM01000036.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB14721; CAB14721; BSU_27620

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
937538

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU27620

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.3001

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA Translation: CAB14721.1
PIRiH69980
RefSeqiNP_390640.1, NC_000964.3
WP_003246110.1, NZ_JNCM01000036.1

3D structure databases

SMRiO32044
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU27620

Proteomic databases

PaxDbiO32044
PRIDEiO32044

Genome annotation databases

EnsemblBacteriaiCAB14721; CAB14721; BSU_27620
GeneIDi937538
KEGGibsu:BSU27620
PATRICifig|224308.179.peg.3001

Phylogenomic databases

eggNOGiCOG0608, Bacteria
COG4199, Bacteria
InParanoidiO32044
OMAiFIICDHH
PhylomeDBiO32044

Enzyme and pathway databases

BioCyciBSUB:BSU27620-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR001667, DDH_dom
IPR038763, DHH_sf
IPR003156, DHHA1_dom
IPR004610, RecJ
IPR018779, RecJ_C
IPR041122, RecJ_OB
PfamiView protein in Pfam
PF01368, DHH, 1 hit
PF02272, DHHA1, 1 hit
PF17768, RecJ_OB, 1 hit
PF10141, ssDNA-exonuc_C, 1 hit
SUPFAMiSSF64182, SSF64182, 1 hit
TIGRFAMsiTIGR00644, recJ, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRECJ_BACSU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O32044
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: January 1, 1998
Last modified: April 7, 2021
This is version 108 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again