The new UniProt website is here!
Take me to UniProt BETA
UniProtKB - O32034 (TRHP1_BACSU)
Protein
tRNA hydroxylation protein P1
Gene
trhP1
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Involved in prephenate-dependent formation of 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs, the first step in 5-methoxyuridine (mo5U) biosynthesis.
1 PublicationGO - Molecular functioni
- peptidase activity Source: UniProtKB-KW
GO - Biological processi
- tRNA modification Source: UniProtKB
Keywordsi
Molecular function | Hydrolase, Protease |
Biological process | tRNA processing |
Enzyme and pathway databases
BioCyci | BSUB:BSU27340-MONOMER |
Protein family/group databases
MEROPSi | U32.002 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:trhP11 Publication Synonyms:yrrO Ordered Locus Names:BSU27340 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
Pathology & Biotechi
Disruption phenotypei
Deletion mutant lacking both trhP1 and trhP2 shows reduced 5-methoxyuridine (mo5U) formation in tRNAs.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000360803 | 1 – 422 | tRNA hydroxylation protein P1Add BLAST | 422 |
Proteomic databases
jPOSTi | O32034 |
PaxDbi | O32034 |
PRIDEi | O32034 |
Interactioni
Protein-protein interaction databases
IntActi | O32034, 1 interactor |
STRINGi | 224308.BSU27340 |
Structurei
3D structure databases
AlphaFoldDBi | O32034 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Sequence similaritiesi
Belongs to the peptidase U32 family.Curated
Phylogenomic databases
eggNOGi | COG0826, Bacteria |
InParanoidi | O32034 |
OMAi | YGGVSHF |
PhylomeDBi | O32034 |
Family and domain databases
InterProi | View protein in InterPro IPR001539, Peptidase_U32 IPR032525, Peptidase_U32_C |
Pfami | View protein in Pfam PF01136, Peptidase_U32, 1 hit PF16325, Peptidase_U32_C, 1 hit |
PROSITEi | View protein in PROSITE PS01276, PEPTIDASE_U32, 1 hit |
i Sequence
Sequence statusi: Complete.
O32034-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTAVNDKIST IVNGKRVITK KPELLAPAGN LEKLKIAVHY GADAVFIGGQ
60 70 80 90 100
EYGLRSNADN FTIEEIAEGV EFAKKYGAKI YVTTNIFAHN ENMDGLEDYL
110 120 130 140 150
KALGDANVAG IIVADPLIIE TCRRVAPNVE VHLSTQQSLS NWKAVQFWKE
160 170 180 190 200
EGLDRVVLAR ETSALEIREM KEKVDIEIES FIHGAMCIAY SGRCVLSNHM
210 220 230 240 250
TARDSNRGGC CQSCRWDYDL YQTDGANAVA LYGEEDAPFA MSPKDLKLIE
260 270 280 290 300
SIPKMIEMGI DSLKIEGRMK SIHYVATVVS VYRKVIDAYC ADPENFVIQK
310 320 330 340 350
EWLEELDKCA NRDTATAFFE GTPGYEEQMF GEHAKKTTYD FVGLVLNYDE
360 370 380 390 400
DTQMVTLQQR NFFKKGDEVE FFGPEIENFT HTIETIWDED GNELDAARHP
410 420
LQIVKFKLDK KIYPSNMMRK GK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009126 Genomic DNA Translation: CAB14676.1 |
PIRi | H69979 |
RefSeqi | NP_390612.1, NC_000964.3 WP_003229802.1, NZ_JNCM01000036.1 |
Genome annotation databases
EnsemblBacteriai | CAB14676; CAB14676; BSU_27340 |
GeneIDi | 937561 |
KEGGi | bsu:BSU27340 |
PATRICi | fig|224308.179.peg.2970 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009126 Genomic DNA Translation: CAB14676.1 |
PIRi | H69979 |
RefSeqi | NP_390612.1, NC_000964.3 WP_003229802.1, NZ_JNCM01000036.1 |
3D structure databases
AlphaFoldDBi | O32034 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | O32034, 1 interactor |
STRINGi | 224308.BSU27340 |
Protein family/group databases
MEROPSi | U32.002 |
Proteomic databases
jPOSTi | O32034 |
PaxDbi | O32034 |
PRIDEi | O32034 |
Genome annotation databases
EnsemblBacteriai | CAB14676; CAB14676; BSU_27340 |
GeneIDi | 937561 |
KEGGi | bsu:BSU27340 |
PATRICi | fig|224308.179.peg.2970 |
Phylogenomic databases
eggNOGi | COG0826, Bacteria |
InParanoidi | O32034 |
OMAi | YGGVSHF |
PhylomeDBi | O32034 |
Enzyme and pathway databases
BioCyci | BSUB:BSU27340-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR001539, Peptidase_U32 IPR032525, Peptidase_U32_C |
Pfami | View protein in Pfam PF01136, Peptidase_U32, 1 hit PF16325, Peptidase_U32_C, 1 hit |
PROSITEi | View protein in PROSITE PS01276, PEPTIDASE_U32, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | TRHP1_BACSU | |
Accessioni | O32034Primary (citable) accession number: O32034 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 20, 2009 |
Last sequence update: | January 1, 1998 | |
Last modified: | May 25, 2022 | |
This is version 101 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Peptidase families
Classification of peptidase families and list of entries - SIMILARITY comments
Index of protein domains and families