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UniProtKB - O31782 (PKSN_BACSU)

Entry version 136 (07 Apr 2021)
Sequence version 3 (05 May 2009)
Previous versions | rss
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Protein

Polyketide synthase PksN

Gene

pksN

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.2 Publications

Miscellaneous

The acyl carrier 1 domain binds alanine.

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

pantetheine 4'-phosphateCuratedNote: Binds 3 phosphopantetheines covalently.Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: bacillaene biosynthesis

This protein is involved in the pathway bacillaene biosynthesis, which is part of Antibiotic biosynthesis.
View all proteins of this organism that are known to be involved in the pathway bacillaene biosynthesis and in Antibiotic biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1261For beta-ketoacyl synthase 1 activityPROSITE-ProRule annotation1
Active sitei2747For beta-ketoacyl synthase 2 activityPROSITE-ProRule annotation1
Active sitei4245For beta-ketoacyl synthase 3 activityPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionAcyltransferase, Ligase, Multifunctional enzyme, Transferase
LigandNADP

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		BSUB:BSU17210-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA01003

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Polyketide synthase PksN (EC:2.3.1.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:pksN
Ordered Locus Names:BSU17210
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003795661 – 5488Polyketide synthase PksNAdd BLAST5488

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1018O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1 Publication1
Modified residuei2485O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei3986O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O31782

PRoteomics IDEntifications database

More...PRIDEi		O31782

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		224308.BSU17210

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O31782

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati165 – 205WD 1Add BLAST41
Repeati965 – 1006WD 2Add BLAST42
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini983 – 1058Carrier 1PROSITE-ProRule annotationAdd BLAST76
Repeati2165 – 2204WD 3Add BLAST40
Domaini2448 – 2525Carrier 2PROSITE-ProRule annotationAdd BLAST78
Repeati3666 – 3705WD 4Add BLAST40
Domaini3952 – 4026Carrier 3PROSITE-ProRule annotationAdd BLAST75
Repeati5206 – 5244WD 5Add BLAST39

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni3 – 301CondensationAdd BLAST299
Regioni493 – 903AdenylationAdd BLAST411
Regioni1092 – 1518Beta-ketoacyl synthase 1Add BLAST427
Regioni2579 – 3015Beta-ketoacyl synthase 2Add BLAST437
Regioni4079 – 4514Beta-ketoacyl synthase 3Add BLAST436

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3038 – 3109Sequence analysisAdd BLAST72
Coiled coili3626 – 3655Sequence analysisAdd BLAST30
Coiled coili5275 – 5303Sequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1176 – 1181Poly-Leu6

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.Curated

Keywords - Domaini

Coiled coil, Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		COG1020, Bacteria
COG1028, Bacteria
COG3321, Bacteria
COG4221, Bacteria

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O31782

Identification of Orthologs from Complete Genome Data

More...OMAi		TYAWKAI

Database for complete collections of gene phylogenies

More...PhylomeDBi		O31782

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1200.10, 3 hits
3.10.129.110, 3 hits
3.30.559.10, 1 hit
3.40.47.10, 3 hits
3.40.50.12780, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR018201, Ketoacyl_synth_AS
IPR014031, Ketoacyl_synth_C
IPR014030, Ketoacyl_synth_N
IPR036291, NAD(P)-bd_dom_sf
IPR032821, PKS_assoc
IPR020841, PKS_Beta-ketoAc_synthase_dom
IPR020807, PKS_dehydratase
IPR042104, PKS_dehydratase_sf
IPR013968, PKS_KR
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR016039, Thiolase-like

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00501, AMP-binding, 1 hit
PF13193, AMP-binding_C, 1 hit
PF00668, Condensation, 1 hit
PF16197, KAsynt_C_assoc, 3 hits
PF00109, ketoacyl-synt, 3 hits
PF02801, Ketoacyl-synt_C, 3 hits
PF08659, KR, 3 hits
PF00550, PP-binding, 3 hits
PF14765, PS-DH, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00826, PKS_DH, 3 hits
SM00825, PKS_KS, 3 hits
SM00823, PKS_PP, 3 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47336, SSF47336, 3 hits
SSF51735, SSF51735, 4 hits
SSF53901, SSF53901, 3 hits

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01733, AA-adenyl-dom, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00455, AMP_BINDING, 1 hit
PS00606, B_KETOACYL_SYNTHASE, 2 hits
PS50075, CARRIER, 3 hits
PS00012, PHOSPHOPANTETHEINE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O31782-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKRQLKSPLS EGQKGLWMLQ KMSPGMSAYN IPLCFRFSKP IHAETFKKAL 
        60         70         80         90        100
LFVQRQYPVL ASVIQEENGI PFQSVQLSKD LYFVEEDISA MKSADIMPFL 
       110        120        130        140        150
KEKAKEPFQL EAGPLWRTHL FHRLEECIVL ITIHHIIFDG VSMLTLISAL 
       160        170        180        190        200
FEAYQQLLNG IEPLQQPSTA DYYDFVDWEN RMLTGREGEE HLAYWKEQLS 
       210        220        230        240        250
GSLPVLDLPA DRPRSSARKF KGQAYKSLLP HHLRNQIKSF ARTNHVNESV 
       260        270        280        290        300
VFLSIYKVLL HHYTKQKDII VGVPTMGRQE DRFETLIGYF INMMAVRSKN 
       310        320        330        340        350
IGSQPLTAFI RELQLTVAVG LDHAAFPFPA LVRELNVDRS AADSPVFQTA 
       360        370        380        390        400
FLYQNFFQAT GLQKVLEPYQ TLGIEYIEDI RQEGEFELAL EIYEQENETV 
       410        420        430        440        450
LHLLYNPDLY ELSSIESMME NYMKLAQHMM EDPSLPLEAY SLQLNQEQTS 
       460        470        480        490        500
LLEQWNATGT NIANDKCIHE VFEEKAKQTP DAVAVMFEDR SLTYKEVDEK 
       510        520        530        540        550
STSVAVYLQH QGVRPEQPVG ICAERSFDMI IGILGILKAG GAYVPLDPSF 
       560        570        580        590        600
PQERLKYMLK DSQASIVLTQ PNVHDRISGL TGSHVKAINI ELACRNGYTD 
       610        620        630        640        650
QQSSGLKREV KPEHLAYIIY TSGSTGEPKG VMVEHRSIMN TLNFLESHYP 
       660        670        680        690        700
VTAEDAYLLK TNYVFDVSIS ELFGWFIGDG RLVILPPNGE KSPQLCMDYI 
       710        720        730        740        750
ETYKVTHINF VPAMLHVFLE MAKDNKRFTE DGPLKYMMVA GEAFPKVLVK 
       760        770        780        790        800
KAVSLFTNCR VENIYGPTEA SIYAAYFGCG KGDIASHHTP IGKPVSNTKI 
       810        820        830        840        850
YIVDQHLKPV PIGKPGELCI AGAGLARGYF KKPGLTAEKF IDNPFESGTK 
       860        870        880        890        900
LYKSGDSARW LPDGNIEYLG RIDSQVKIRG FRVELGAIET KLGEFPGILD 
       910        920        930        940        950
QAVVVKQLEG HQQLAAYYTE ESGHASANPK DLRLHLKSSL PEYMIPSHFI 
       960        970        980        990       1000
RLDELPLSPS GKVNRKELEK REIVFNRRKP NHLQLTEIED QVLRIWEETL 
      1010       1020       1030       1040       1050
KVSGFGPEDG FFDAGGDSLL AVAVAERIKK EFDCEFHVTE LFEYSTIRAI 
      1060       1070       1080       1090       1100
SEYILEMKNS DLAGTQNEDD HDDKKDGKYP KQKIPPYFDD SVAIVGISCQ 
      1110       1120       1130       1140       1150
FPGAKNHHDF WNHIKEGKES IRFFSEEELR ANGVPEELIQ HPDYVPVQSV 
      1160       1170       1180       1190       1200
IEGKDLFDPG FFQISPKDAE YMDPQLRLLL LHSWKAIEDA GYVAKEIPAT 
      1210       1220       1230       1240       1250
SVYMSASSNS YRTLLPKETT EGHESPDGYV SWVLAQSGTI PTMISHKLGL 
      1260       1270       1280       1290       1300
KGPSYFVHSN CSSSLVGLYQ AYKSLTSGES QYALVGGATL HAQSAIGYVH 
      1310       1320       1330       1340       1350
QNGLNFSSDG HVKAFDASAD GMAGGEGVAV ILLKKAVDAV KDGDHIYAIM 
      1360       1370       1380       1390       1400
RGIGINNDGA EKAGFYAPSV KGQTEVIQHV LDTTKIHPET VSYIEAHGTG 
      1410       1420       1430       1440       1450
TKLGDPIEMS ALNKVYKQYT DKTQFCGIGS VKTNIGHLDT AAGLAGCIKV 
      1460       1470       1480       1490       1500
AMSLYHNELA PTINCTEPNP DIKFESSPFY VVRERKSLEK HAGVHRAALS 
      1510       1520       1530       1540       1550
SFGLGGTNAH AIFEQYENIS DAGAENEGNQ PYIIPISAKN SERLQVYAKE 
      1560       1570       1580       1590       1600
MLSYISQDEQ RHFSLRDIAY TFQVGREAMD NRIVFIVNDL EEWKHQLEAF 
      1610       1620       1630       1640       1650
VTGKPLAEGC IQGEKTRMTS AEQLLGNAEA DDMASSRISK EELRKLAEMW 
      1660       1670       1680       1690       1700
ANGFHVEWRR LYPNIKPRRI SLPTYPFAEE RYWPESSTGA ITTIEPSRLH 
      1710       1720       1730       1740       1750
PLVHHNTSVL SEQRFSSIFT GQEYFIAEHI IKGMAILPAA VTLEMARAAI 
      1760       1770       1780       1790       1800
EQGIGGLEDH ETGIRLKNVV WVRPVVAGSE PVQVNIGLYD EDGGHIAYRM 
      1810       1820       1830       1840       1850
YGDPESADAE PVVYNQGKAE LIQLKREKAL DLSKIKKQCD QSKMDAASFY 
      1860       1870       1880       1890       1900
EGMIGADYGP GYKSVEAVYK GDGQLLAKLS LPESVAHTLG DYVLHPSVMD 
      1910       1920       1930       1940       1950
GALQAAEYLQ NVVRAELSDT EDFKAALPFA LEELEVFRQC VSDMWVYVQF 
      1960       1970       1980       1990       2000
NSKNKPGDLI QKVDIHLCDE HGMICVRLKG FSTRVMEADI QTEPSKINAE 
      2010       2020       2030       2040       2050
TLLLQPVWQE QKAANSLAAK KYAEHLVFLC EYDHETRKQI EAAIEDVHVY 
      2060       2070       2080       2090       2100
SLEARPSSVD GRFHSYTEQV FKKVQEIIRT KPKDGILVQI VTSAEGEQQL 
      2110       2120       2130       2140       2150
FSGLTGLLKT ACQENAKLTG QMIEVSSEES GESIAGKLLE NQMSSDSYVK 
      2160       2170       2180       2190       2200
YQNGTRYIAD WREIKQAKGD GSKPWKDNGV YLISGGAGGL GHIFAKEIAE 
      2210       2220       2230       2240       2250
QTKNATVILA GRSPLSESKS KKLKELHSKG ADITYRQTDV TNKIEVYQLI 
      2260       2270       2280       2290       2300
DDIQKRYGRL NGILHSAGII KDSYLVNKQA KDLHDVLAPK VKGLVYLDEA 
      2310       2320       2330       2340       2350
SKDLPLDFFI LFSSLSGSLG SIGQSDYAAA NVFMDMYAGY RNRLADLSQR 
      2360       2370       2380       2390       2400
HGQTLSVNWP LWRDGGMQVD QETEKRLVQL AGIVPMRAEK GIQALYQALH 
      2410       2420       2430       2440       2450
SEANQVMVIE GDVQKIKQNM LAKNASAPME KKEAEHMTEQ INSIDADSLL 
      2460       2470       2480       2490       2500
DKVKAMLKRE IAKLLKVKLE TIDDHAEMTV YGFDSISMTE FTNHINRAYQ 
      2510       2520       2530       2540       2550
LELTPTVFFD HPTIHAFGKH LSEEYQSVFA KTFAVRAVSA QLQPAAKQEQ 
      2560       2570       2580       2590       2600
AVRAKAKRRR KQQVMLPNAI QSDAGPEPIA IVGISGIFPM AKDVEAYWNI 
      2610       2620       2630       2640       2650
LKEGKDCMTE IPKDRWDWRE YEGDPAKEVN KTNVKWGGFI DGIADFDPLF 
      2660       2670       2680       2690       2700
FGISPREAEQ MEPQQRLLLT YAWKAIEDAG YSAKRLSGTK TGVFIGTGNT 
      2710       2720       2730       2740       2750
GYSSLLSKAN SAIEGSAAAN TSPSVGPNRV SYFLNLHGPS EPVDTACSSS 
      2760       2770       2780       2790       2800
LVAIHHAISS IEEGTCDMAL AGGVNTIILP EVYISFDKAG ALSKEGKCKT 
      2810       2820       2830       2840       2850
FSNQADGFAH GEGAGILFLK KLKAAEEAGD HIYGVIKGSA INHGGRAASL 
      2860       2870       2880       2890       2900
TTPNPKAQAD VIQSAYQKAG IDPKTVTYIE AHGTGTELGD PVEINGLKSA 
      2910       2920       2930       2940       2950
FKALGVNEGD TSANPYCGLG SVKTNIGHLS LAAGAAGVIK ILLQLKHKTL 
      2960       2970       2980       2990       3000
VKSLHCENVN PYIQLKNSPF YIVRETEEWK ALKNEQGEEL PRRAGVSSFG 
      3010       3020       3030       3040       3050
IGGVNAHVII EEYIPEASDE NIPSIAPEHP GIFVLSAKNE ARLKEHAQQL 
      3060       3070       3080       3090       3100
ADALDKQTYS DVNLARIAYT LQAGRDAMEE RLGIISGSIE DLQKKLKDFA 
      3110       3120       3130       3140       3150
AEKSGVEDVF KGRIDKGTLQ MLTEDEEIQE AVEKWMERGK YAKLLELWVK 
      3160       3170       3180       3190       3200
GLDVDWTKLY GENLPKRISL PTYPFAKDRY WISDHIEKSG SIDANQAASR 
      3210       3220       3230       3240       3250
LGGAVLHPLM HQNTSNLSEQ RFSSIYTGEE FFLADHVVKG QRILPGVAHL 
      3260       3270       3280       3290       3300
ELARAAVEQA AEVQGVPRIM KLKNAVWVRP IVVEDQPQQV HIRLLPGENG 
      3310       3320       3330       3340       3350
EISYEIYGHS DVTGEQSIVY SQGSAVLNPA ENLPAVDLQS LREQCQESHF 
      3360       3370       3380       3390       3400
SVNEVYDTYR MIGFEYGPAY RGVKKIYTAE QFVLAKLSLH PSAADTLSQY 
      3410       3420       3430       3440       3450
KMHPGLMDSA LQASSILTGA GDNQLTLPFA VQELEVFGAC SSEMWVYARY 
      3460       3470       3480       3490       3500
SQGSKATDKV QKRDMDILDE SGNVCVRMKG LSFRAAEGGS GSAESDQTLA 
      3510       3520       3530       3540       3550
TLMFEEKWVP KDFKKESPEP HYERHIVMLC DMNGLSKDRI ESRMTGAECI 
      3560       3570       3580       3590       3600
VLESFREGLA ERFQDYAEQA LETVQGLLKS RPQGNVLIQL LTSAQRKQYS 
      3610       3620       3630       3640       3650
FSGLSALLKT AGLENKKLIG QTIEIDSHEN VESVIEKLKE NKRHTEDQHI 
      3660       3670       3680       3690       3700
KYEKGKRYIN DLDEMQIDDR EISMPWRDKG VYLITGGAGG LGFIFAKEIA 
      3710       3720       3730       3740       3750
RQAEQPVLIL TGRSALNADQ QAELNELQQL GARAEYRQVD VTQTEAASEL 
      3760       3770       3780       3790       3800
ITSITSDYED LNGVIHSAGL IKDNYLMSKT NEELTQVLAP KVKGLVNVDE 
      3810       3820       3830       3840       3850
ATEHLALDFF ILFSSISSVA GSAGQADYAM ANAFMDSYAA YRNALVTAMY 
      3860       3870       3880       3890       3900
RHGQTLSINW PLWKEGGMRA NKEIENMTLK NTGVTPMRTE TGIQALYKGL 
      3910       3920       3930       3940       3950
AFGKDQVIVM EGFKDMMREK LTQKPSSDDV PMKTVQVRVT SEARMDQGNM 
      3960       3970       3980       3990       4000
FDHIQEVLKQ TISQLLKIKP EEIDPDMEFN QYGFDSITLT EFANTLNEKC 
      4010       4020       4030       4040       4050
KLDLTPTVFF EHATVYAFAG YLSEEYPNAF TAQTPAKAEV LMQPVEQNIK 
      4060       4070       4080       4090       4100
NMTFSTENRF VKPSVTPMQK EADHKPEPIA IVGMSGVFPK AKDVEEYWKN 
      4110       4120       4130       4140       4150
LSSGADCITE VPKDRWDWQE YYGDPLKEAN KTNVKWGGFI DEVADFDPLF 
      4160       4170       4180       4190       4200
FGISPLEAEQ MEPQQRLLMT YAWKAVEEAG HSARSLAGTK TGIFIGTGNT 
      4210       4220       4230       4240       4250
GYSSLLSNVD IEGSAAANMS PSAGPNRVSY FLNIHGPSEP IDTACSSSLV 
      4260       4270       4280       4290       4300
AIHHAVCAIE NGNCEMAIAG GVNTVVTPQG HIAYDKAGAL SKEGRCKTFS 
      4310       4320       4330       4340       4350
DKADGFAVSE GAGILFLKKL TAAERDGDHI YGVIKGSAVN HGGRANSLTT 
      4360       4370       4380       4390       4400
PNPKAQADVV KTAYEKAGID PRTVTYIEAH GTGTELGDPV EINGLKAAFK 
      4410       4420       4430       4440       4450
ELYEKTGDPA VHGSHCGLGS AKTNIGHLSL AAGVAGVIKV LLQLKHKTLV 
      4460       4470       4480       4490       4500
KSLYSETVNP YIRLDDSPFY IVQESREWQA LRDEAGRELP RRAGISSFGI 
      4510       4520       4530       4540       4550
GGVNAHVVIE EYIPKETTHP ATAPAVTAQH PGIFILSAKD EDRLKDQARQ 
      4560       4570       4580       4590       4600
LADFISKRSI TARDLTDIAY TLQEGRDAME ERLGIIAVST GDLLEKLNLF 
      4610       4620       4630       4640       4650
IEGGTNAKYM YRGRAEKGIA QTLRSDDEVQ KTLNNSWEPH IYERLLDLWV 
      4660       4670       4680       4690       4700
KGMEIGWSKL YDGKQPKRIS LPTYPFAKER YWITDTKEEA AAHQTALKTV 
      4710       4720       4730       4740       4750
ESAALHPLIH VNTSDLSEQR FSSAFTGAEF FFADHKVKGK PVMPGVAYLE 
      4760       4770       4780       4790       4800
MVHAAVTRAV RRTEDQQSVI HIKNVVWVQP IVADGQPVQV DISLNPQQDG 
      4810       4820       4830       4840       4850
EIAFNVYTEA AHNDRKIHCQ GSASIRGAGD IPVQDISALQ DQCSLSTLSH 
      4860       4870       4880       4890       4900
DQCYELFKAI GIDYGPGFQG IDRLYIGRNQ ALAELSLPAG VTHTLNEFVL 
      4910       4920       4930       4940       4950
HPSMADSALQ ASIGLKLNSG DEQLSLPFAL QELEIFSPCT NKMWVSVTSR 
      4960       4970       4980       4990       5000
PNEDKIQRLD IDLCDEQGRV CVRIKGITSR LLEEGIQPPD GPTSLGNSKA 
      5010       5020       5030       5040       5050
TLNGALLMAP IWDRVQLEKR SISPADERVV ILGGDDNSRK AVQREFPFAK 
      5060       5070       5080       5090       5100
ELYIEPNASI HRITGQLEAL GSFDHIVWMS PSRVTECEVG DEMIEAQDQG 
      5110       5120       5130       5140       5150
VIQMYRLIKA MLSLGYGQKE ISWTIVTVNT QYVDQHDIVD PVDAGVHGLI 
      5160       5170       5180       5190       5200
GSMSKEYPNW QTKLIDVKKY EDLPLSQLLS LPADQEGNTW AYRNKIWHKL 
      5210       5220       5230       5240       5250
RLIPVHNNQP VHTKYKHGGV YVVIGGAGGI GEAWSEYMIR TYQAQIVWIG 
      5260       5270       5280       5290       5300
RRKKDAAIQS KLDRFARLGR APYYIQADAA NREELERAYE TMKQTHREIN 
      5310       5320       5330       5340       5350
GIIHSAIVLQ DRSLMNMSEE CFRNVLAAKV DVSVRMAQVF RHEPLDFVLF 
      5360       5370       5380       5390       5400
FSSVQSFARA SGQSNYAAGC SFKDAFAQRL SQVWPCTVAV MNWSYWGSIG 
      5410       5420       5430       5440       5450
VVSSPDYQKR MAQAGIGSIE APEAMEALEL LLGGPLKQLV MMKMANETND 
      5460       5470       5480 
EAEQTEETIE VYPETHGSAI QKLRSYHPGD NTKIQQLL
Length:5,488
Mass (Da):609,593
Last modified:May 5, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1EA0D0F91C78FDDD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AL009126 Genomic DNA Translation: CAB13604.3

NCBI Reference Sequences

More...RefSeqi		NP_389602.3, NC_000964.3
WP_010886514.1, NZ_CP053102.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		CAB13604; CAB13604; BSU_17210

Database of genes from NCBI RefSeq genomes

More...GeneIDi		940054

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		bsu:BSU17210

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|224308.43.peg.1817

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL009126 Genomic DNA Translation: CAB13604.3
RefSeqiNP_389602.3, NC_000964.3
WP_010886514.1, NZ_CP053102.1

3D structure databases

SMRiO31782
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU17210

Proteomic databases

PaxDbiO31782
PRIDEiO31782

Genome annotation databases

EnsemblBacteriaiCAB13604; CAB13604; BSU_17210
GeneIDi940054
KEGGibsu:BSU17210
PATRICifig|224308.43.peg.1817

Phylogenomic databases

eggNOGiCOG1020, Bacteria
COG1028, Bacteria
COG3321, Bacteria
COG4221, Bacteria
InParanoidiO31782
OMAiTYAWKAI
PhylomeDBiO31782

Enzyme and pathway databases

UniPathwayiUPA01003
BioCyciBSUB:BSU17210-MONOMER

Family and domain databases

Gene3Di1.10.1200.10, 3 hits
3.10.129.110, 3 hits
3.30.559.10, 1 hit
3.40.47.10, 3 hits
3.40.50.12780, 1 hit
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR025110, AMP-bd_C
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, AMP-dep_Synthh-like_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR018201, Ketoacyl_synth_AS
IPR014031, Ketoacyl_synth_C
IPR014030, Ketoacyl_synth_N
IPR036291, NAD(P)-bd_dom_sf
IPR032821, PKS_assoc
IPR020841, PKS_Beta-ketoAc_synthase_dom
IPR020807, PKS_dehydratase
IPR042104, PKS_dehydratase_sf
IPR013968, PKS_KR
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
IPR006162, Ppantetheine_attach_site
IPR016039, Thiolase-like
PfamiView protein in Pfam
PF00501, AMP-binding, 1 hit
PF13193, AMP-binding_C, 1 hit
PF00668, Condensation, 1 hit
PF16197, KAsynt_C_assoc, 3 hits
PF00109, ketoacyl-synt, 3 hits
PF02801, Ketoacyl-synt_C, 3 hits
PF08659, KR, 3 hits
PF00550, PP-binding, 3 hits
PF14765, PS-DH, 3 hits
SMARTiView protein in SMART
SM00826, PKS_DH, 3 hits
SM00825, PKS_KS, 3 hits
SM00823, PKS_PP, 3 hits
SUPFAMiSSF47336, SSF47336, 3 hits
SSF51735, SSF51735, 4 hits
SSF53901, SSF53901, 3 hits
TIGRFAMsiTIGR01733, AA-adenyl-dom, 1 hit
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 1 hit
PS00606, B_KETOACYL_SYNTHASE, 2 hits
PS50075, CARRIER, 3 hits
PS00012, PHOSPHOPANTETHEINE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPKSN_BACSU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O31782
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: May 5, 2009
Last modified: April 7, 2021
This is version 136 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
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