UniProtKB - O31501 (SWRC_BACSU)
Protein
Swarming motility protein SwrC
Gene
swrC
Organism
Bacillus subtilis (strain 168)
Status
Functioni
Required for self-resistance to surfactin, an antimicrobial lipopeptide surfactant produced by B.subtilis. Also required for swarming motility.2 Publications
Miscellaneous
A SwrC-deficient strain is susceptible to acriflavine and ethidium bromide, and showed severer growth inhibition as surfactin concentration increased up to 100ug/ml.
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
GO - Biological processi
- response to antibiotic Source: UniProtKB-KW
Keywordsi
Biological process | Antibiotic resistance |
Enzyme and pathway databases
BioCyci | BSUB:BSU06710-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Swarming motility protein SwrC |
Gene namesi | Name:swrC Ordered Locus Names:BSU06710 |
Organismi | Bacillus subtilis (strain 168) |
Taxonomic identifieri | 224308 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000161847 | 1 – 1052 | Swarming motility protein SwrCAdd BLAST | 1052 |
Proteomic databases
jPOSTi | O31501 |
PaxDbi | O31501 |
PRIDEi | O31501 |
Expressioni
Inductioni
Not induced by surfactin.
Interactioni
Binary interactionsi
Hide detailsO31501
Protein-protein interaction databases
IntActi | O31501, 63 interactors |
STRINGi | 224308.BSU06710 |
Family & Domainsi
Sequence similaritiesi
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. [View classification]Curated
Phylogenomic databases
eggNOGi | COG0841, Bacteria |
InParanoidi | O31501 |
OMAi | WRGVRTD |
Family and domain databases
InterProi | View protein in InterPro IPR027463, AcrB_DN_DC_subdom IPR001036, Acrflvin-R |
PANTHERi | PTHR32063, PTHR32063, 1 hit |
Pfami | View protein in Pfam PF00873, ACR_tran, 1 hit |
PRINTSi | PR00702, ACRIFLAVINRP |
SUPFAMi | SSF82714, SSF82714, 2 hits |
i Sequence
Sequence statusi: Complete.
O31501-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNHVINFVLK NKFAVWLMTI IVTAAGLYAG MNMKQESIPD VNMPYLTIST
60 70 80 90 100
TYPGATPSQV ADEVTKPVEQ AVQNLDGVSV VTSTSYENAS SVMIEYDYEK
110 120 130 140 150
DMDKAKTEAA EALENVNLPD DAKDPEISRY SLNSFPILTL SVSSDKDNLQ
160 170 180 190 200
ELTKQVEDSL VSKLEGIEGV ASVQVSGQQV EEVEFSFKED KLKEYGLDED
210 220 230 240 250
TVKQVIQGSD VTTPLGLYTF GNEEKSVVVS GDIETIKDLK NMRIPTASAS
260 270 280 290 300
SAGSSAASQA GAQSAQAAQS AQAAAQVQQS ASTAVPTVKL SDIATIKDVK
310 320 330 340 350
KAESVSRTNG KDSIGINIVK ANDANTVEVA DDVKAELKKF KEDHKGFNYS
360 370 380 390 400
ATLDMAEPIT QSVDTMLSKA IFGAIFAIVI ILLFLRDIKS TLISVVSIPL
410 420 430 440 450
SLLIALLVLQ QLDITLNIMT LGAMTVAIGR VVDDSIVVIE NIYRRMRLKD
460 470 480 490 500
EPLRGKALVR EATKEMFKPI MSSTIVTIAV FLPLALVGGQ IGELFIPFAL
510 520 530 540 550
TIVFALAASL VISITLVPML AHSLFKKSLT GAPIKAKEHK PGRLANIYKK
560 570 580 590 600
VLNWALSHKW ITSIIAVLML LGSLFLVPLI GASYLPSEEE KTMQLTYSPE
610 620 630 640 650
PGETKKEAEN EAEKAEKILL DRKHVDTVQY SLGSGSPLAG GDSNGALFYI
660 670 680 690 700
KYESDTPDFD KEKDNVLKEI QKQSDRGEWK SQDFSSSGNN NELTYYVYGD
710 720 730 740 750
SENDIKDTVK DIEKIMKDEK DLKNVNSGLS STYDEYTFVA DQEKLSKLGL
760 770 780 790 800
TASQISQALM SQTSQEPLTT VKKDGKELDV NIKTEKDEYK SVKDLENKKI
810 820 830 840 850
TSATGQEVKI GDVAKVKEGS TSDTVSKRDG KVYADVTGEV TSDNVTAVSA
860 870 880 890 900
AIQKKIDKLD HPDNVSIDTG GVSADIADSF TKLGLAMLAA IAIVYLVLVI
910 920 930 940 950
TFGGALAPFA ILFSLPFTVI GALVGLYVSG ETISLNAMIG MLMLIGIVVT
960 970 980 990 1000
NAIVLIDRVI HKEAEGLSTR EALLEAGSTR LRPILMTAIA TIGALIPLAL
1010 1020 1030 1040 1050
GFEGGSQVIS KGLGVTVIGG LISSTLLTLL IVPIVYEVLA KFRKKKPGTE
EE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009126 Genomic DNA Translation: CAB12491.2 |
PIRi | E69795 |
RefSeqi | NP_388553.1, NC_000964.3 WP_003242663.1, NZ_JNCM01000032.1 |
Genome annotation databases
EnsemblBacteriai | CAB12491; CAB12491; BSU06710 |
GeneIDi | 938055 |
KEGGi | bsu:BSU06710 |
PATRICi | fig|224308.179.peg.729 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL009126 Genomic DNA Translation: CAB12491.2 |
PIRi | E69795 |
RefSeqi | NP_388553.1, NC_000964.3 WP_003242663.1, NZ_JNCM01000032.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | O31501, 63 interactors |
STRINGi | 224308.BSU06710 |
Proteomic databases
jPOSTi | O31501 |
PaxDbi | O31501 |
PRIDEi | O31501 |
Genome annotation databases
EnsemblBacteriai | CAB12491; CAB12491; BSU06710 |
GeneIDi | 938055 |
KEGGi | bsu:BSU06710 |
PATRICi | fig|224308.179.peg.729 |
Phylogenomic databases
eggNOGi | COG0841, Bacteria |
InParanoidi | O31501 |
OMAi | WRGVRTD |
Enzyme and pathway databases
BioCyci | BSUB:BSU06710-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR027463, AcrB_DN_DC_subdom IPR001036, Acrflvin-R |
PANTHERi | PTHR32063, PTHR32063, 1 hit |
Pfami | View protein in Pfam PF00873, ACR_tran, 1 hit |
PRINTSi | PR00702, ACRIFLAVINRP |
SUPFAMi | SSF82714, SSF82714, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SWRC_BACSU | |
Accessioni | O31501Primary (citable) accession number: O31501 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | September 13, 2004 |
Last sequence update: | September 13, 2004 | |
Last modified: | December 2, 2020 | |
This is version 103 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families