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Protein

3-carboxy-cis,cis-muconate cycloisomerase

Gene

pcaB

Organism
Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes an anti cycloisomerization.

Catalytic activityi

2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = cis,cis-butadiene-1,2,4-tricarboxylate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processAromatic hydrocarbons catabolism

Enzyme and pathway databases

BioCyciBDIA224911:G1G3J-5713-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
3-carboxy-cis,cis-muconate cycloisomerase (EC:5.5.1.2)
Alternative name(s):
3-carboxymuconate lactonizing enzyme
Short name:
CMLE
Gene namesi
Name:pcaB
Ordered Locus Names:blr5667
OrganismiBradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
Taxonomic identifieri224911 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium
Proteomesi
  • UP000002526 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001613481 – 4513-carboxy-cis,cis-muconate cycloisomeraseAdd BLAST451

Proteomic databases

PRIDEiO31385

Interactioni

Protein-protein interaction databases

STRINGi224911.blr5667

Structurei

3D structure databases

ProteinModelPortaliO31385
SMRiO31385
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II fumarase/aspartase family.Curated

Phylogenomic databases

eggNOGiENOG4107RAW Bacteria
COG0015 LUCA
HOGENOMiHOG000033914
InParanoidiO31385
KOiK01857
OMAiPWHTLRT
OrthoDBiPOG091H0168
PhylomeDBiO31385

Family and domain databases

Gene3Di1.10.275.10, 1 hit
InterProiView protein in InterPro
IPR019468 AdenyloSucc_lyase_C
IPR024083 Fumarase/histidase_N
IPR020557 Fumarate_lyase_CS
IPR000362 Fumarate_lyase_fam
IPR022761 Fumarate_lyase_N
IPR008948 L-Aspartase-like
IPR012789 Protocat_PcaB
PfamiView protein in Pfam
PF10397 ADSL_C, 1 hit
PF00206 Lyase_1, 1 hit
PRINTSiPR00149 FUMRATELYASE
SMARTiView protein in SMART
SM00998 ADSL_C, 1 hit
SUPFAMiSSF48557 SSF48557, 1 hit
TIGRFAMsiTIGR02426 protocat_pcaB, 1 hit
PROSITEiView protein in PROSITE
PS00163 FUMARATE_LYASES, 1 hit

Sequencei

Sequence statusi: Complete.

O31385-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTALSPLLA PMLSSAAMRA ACDDRSTLQN MLDFEAALAR AEAATGVIPA
60 70 80 90 100
AAVGPIETAC KAATFDIAAL AEAATRSGNL AIPLVKALTA NVAKADAEAA
110 120 130 140 150
RYVHWGATSQ DVIDTATMLT LRAAIDALDA DLSRAIKGFA ALARNHRNTA
160 170 180 190 200
MVARTWLQHA LPMPFGLKAA EYAASLARAR CRLRRLSRDG LALQFGGAAG
210 220 230 240 250
TLAALGDKGL VVAERLAQEL NLPLPEAPWH THRDRIAEAA SALAILAGSC
260 270 280 290 300
GKIARDVSLM MQTDVAEAFE PAGEGRGGSS TMPHKRNPVA AASALGCATM
310 320 330 340 350
APQLAATIFA AQVQDHERSA GPWHAEWPTL PQLMLVTSGA LAAIVDIAEG
360 370 380 390 400
LDVDAARMRS NLDATHGLIM AEAVTFALAE RIGKSDAHHL IEAASKRAVA
410 420 430 440 450
EKKHLREVLA ADSQVTAHLS PEKIAALFEP MAYQGASQAM IDRLLDSLER

D
Length:451
Mass (Da):47,238
Last modified:January 1, 1998 - v1
Checksum:iDB6220DA9C5E1981
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10223 Genomic DNA Translation: CAA71270.1
BA000040 Genomic DNA Translation: BAC50932.1
RefSeqiNP_772307.1, NC_004463.1
WP_011088413.1, NC_004463.1

Genome annotation databases

EnsemblBacteriaiBAC50932; BAC50932; BAC50932
GeneIDi1050271
KEGGibja:blr5667
PATRICifig|224911.5.peg.5776

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y10223 Genomic DNA Translation: CAA71270.1
BA000040 Genomic DNA Translation: BAC50932.1
RefSeqiNP_772307.1, NC_004463.1
WP_011088413.1, NC_004463.1

3D structure databases

ProteinModelPortaliO31385
SMRiO31385
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224911.blr5667

Proteomic databases

PRIDEiO31385

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC50932; BAC50932; BAC50932
GeneIDi1050271
KEGGibja:blr5667
PATRICifig|224911.5.peg.5776

Phylogenomic databases

eggNOGiENOG4107RAW Bacteria
COG0015 LUCA
HOGENOMiHOG000033914
InParanoidiO31385
KOiK01857
OMAiPWHTLRT
OrthoDBiPOG091H0168
PhylomeDBiO31385

Enzyme and pathway databases

BioCyciBDIA224911:G1G3J-5713-MONOMER

Family and domain databases

Gene3Di1.10.275.10, 1 hit
InterProiView protein in InterPro
IPR019468 AdenyloSucc_lyase_C
IPR024083 Fumarase/histidase_N
IPR020557 Fumarate_lyase_CS
IPR000362 Fumarate_lyase_fam
IPR022761 Fumarate_lyase_N
IPR008948 L-Aspartase-like
IPR012789 Protocat_PcaB
PfamiView protein in Pfam
PF10397 ADSL_C, 1 hit
PF00206 Lyase_1, 1 hit
PRINTSiPR00149 FUMRATELYASE
SMARTiView protein in SMART
SM00998 ADSL_C, 1 hit
SUPFAMiSSF48557 SSF48557, 1 hit
TIGRFAMsiTIGR02426 protocat_pcaB, 1 hit
PROSITEiView protein in PROSITE
PS00163 FUMARATE_LYASES, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPCAB_BRADU
AccessioniPrimary (citable) accession number: O31385
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: January 1, 1998
Last modified: November 7, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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