Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA polymerase sliding clamp

Gene

pcn

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processDNA replication

Enzyme and pathway databases

BRENDAi3.1.26.4 414

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase sliding clampUniRule annotation
Alternative name(s):
Proliferating cell nuclear antigen homologUniRule annotation
Short name:
PCNAUniRule annotation
Gene namesi
Name:pcnUniRule annotation
Ordered Locus Names:AF_0335
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001491921 – 245DNA polymerase sliding clampAdd BLAST245

Interactioni

Subunit structurei

Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.UniRule annotation

Protein-protein interaction databases

STRINGi224325.AF0335

Structurei

Secondary structure

1245
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi2 – 7Combined sources6
Helixi8 – 19Combined sources12
Beta strandi23 – 30Combined sources8
Beta strandi33 – 39Combined sources7
Beta strandi43 – 52Combined sources10
Helixi53 – 55Combined sources3
Beta strandi56 – 63Combined sources8
Beta strandi65 – 70Combined sources6
Helixi71 – 78Combined sources8
Beta strandi85 – 101Combined sources17
Beta strandi104 – 109Combined sources6
Helixi113 – 115Combined sources3
Beta strandi128 – 134Combined sources7
Helixi135 – 146Combined sources12
Beta strandi150 – 157Combined sources8
Beta strandi160 – 166Combined sources7
Beta strandi171 – 176Combined sources6
Helixi178 – 180Combined sources3
Beta strandi181 – 184Combined sources4
Beta strandi189 – 194Combined sources6
Helixi195 – 201Combined sources7
Helixi202 – 204Combined sources3
Beta strandi210 – 215Combined sources6
Beta strandi217 – 219Combined sources3
Beta strandi221 – 227Combined sources7
Turni228 – 231Combined sources4
Beta strandi232 – 238Combined sources7
Beta strandi241 – 243Combined sources3

3D structure databases

ProteinModelPortaliO29912
SMRiO29912
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO29912

Family & Domainsi

Sequence similaritiesi

Belongs to the PCNA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00488 Archaea
COG0592 LUCA
KOiK04802
OMAiKCANSDD
OrthoDBiPOG093Z0814

Family and domain databases

HAMAPiMF_00317 DNApol_clamp_arch, 1 hit
InterProiView protein in InterPro
IPR000730 Pr_cel_nuc_antig
IPR022649 Pr_cel_nuc_antig_C
IPR022659 Pr_cel_nuc_antig_CS
IPR022648 Pr_cel_nuc_antig_N
PANTHERiPTHR11352:SF0 PTHR11352:SF0, 1 hit
PfamiView protein in Pfam
PF02747 PCNA_C, 1 hit
PF00705 PCNA_N, 1 hit
PRINTSiPR00339 PCNACYCLIN
PROSITEiView protein in PROSITE
PS01251 PCNA_1, 1 hit

Sequencei

Sequence statusi: Complete.

O29912-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIDVIMTGEL LKTVTRAIVA LVSEARIHFL EKGLHSRAVD PANVAMVIVD
60 70 80 90 100
IPKDSFEVYN IDEEKTIGVD MDRIFDISKS ISTKDLVELI VEDESTLKVK
110 120 130 140 150
FGSVEYKVAL IDPSAIRKEP RIPELELPAK IVMDAGEFKK AIAAADKISD
160 170 180 190 200
QVIFRSDKEG FRIEAKGDVD SIVFHMTETE LIEFNGGEAR SMFSVDYLKE
210 220 230 240
FCKVAGSGDL LTIHLGTNYP VRLVFELVGG RAKVEYILAP RIESE
Length:245
Mass (Da):27,267
Last modified:January 1, 1998 - v1
Checksum:i5665CDA0EA393CE3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA Translation: AAB90899.1
PIRiG69291
RefSeqiWP_010877842.1, NC_000917.1

Genome annotation databases

EnsemblBacteriaiAAB90899; AAB90899; AF_0335
GeneIDi24793874
KEGGiafu:AF_0335

Similar proteinsi

Entry informationi

Entry nameiPCNA_ARCFU
AccessioniPrimary (citable) accession number: O29912
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: January 1, 1998
Last modified: March 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health