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Protein
Submitted name:

Cobalamin biosynthesis precorrin-6Y methylase (CbiE)

Gene

AF_0722

Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei103S-adenosyl-L-homocysteineCombined sources1
Binding sitei145S-adenosyl-L-homocysteine; via amide nitrogen and carbonyl oxygenCombined sources1
Binding sitei165S-adenosyl-L-homocysteine; via amide nitrogen and carbonyl oxygenCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Cobalamin biosynthesis precorrin-6Y methylase (CbiE)Imported
Gene namesi
Ordered Locus Names:AF_0722Imported
OrganismiArchaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)Imported
Taxonomic identifieri224325 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaArchaeoglobiArchaeoglobalesArchaeoglobaceaeArchaeoglobus
Proteomesi
  • UP000002199 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi10 ↔ 166Combined sources

Interactioni

Protein-protein interaction databases

STRINGi224325.AF0722

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2BB3X-ray2.27A/B1-197[»]
ProteinModelPortaliO29536
SMRiO29536
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO29536

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 178TP_methylaseInterPro annotationAdd BLAST178

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni74 – 79S-adenosyl-L-homocysteine bindingCombined sources6
Regioni185 – 187S-adenosyl-L-homocysteine bindingCombined sources3

Phylogenomic databases

eggNOGiarCOG00650 Archaea
COG2241 LUCA
KOiK03399
OrthoDBiPOG093Z0FJA

Family and domain databases

CDDicd11644 Precorrin-6Y-methylase, 1 hit
Gene3Di3.30.950.10, 1 hit
3.40.1010.10, 1 hit
InterProiView protein in InterPro
IPR000878 4pyrrol_Mease
IPR035996 4pyrrol_Methylase_sf
IPR014777 4pyrrole_Mease_sub1
IPR014776 4pyrrole_Mease_sub2
IPR012818 Cbl_synth_CbiE
PfamiView protein in Pfam
PF00590 TP_methylase, 1 hit
SUPFAMiSSF53790 SSF53790, 1 hit
TIGRFAMsiTIGR02467 CbiE, 1 hit

Sequencei

Sequence statusi: Complete.

O29536-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIWIVGSGTC RGQTTERAKE IIERAEVIYG SRRALELAGV VDDSRARILR
60 70 80 90 100
SFKGDEIRRI MEEGREREVA VISTGDPMVA GLGRVLREIA EDVEIKIEPA
110 120 130 140 150
ISSVQVALAR LKVDLSEVAV VDCHAKDFDA ELTELLKYRH LLILADSHFP
160 170 180 190
LERLGKRRVV LLENLCMEGE RIREGNADSI ELESDYTIIF VEREVME
Length:197
Mass (Da):22,263
Last modified:January 1, 1998 - v1
Checksum:i9456AE2F36424370
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000782 Genomic DNA Translation: AAB90520.1
PIRiB69340
RefSeqiWP_010878225.1, NC_000917.1

Genome annotation databases

EnsemblBacteriaiAAB90520; AAB90520; AF_0722
GeneIDi25399228
KEGGiafu:AF_0722

Similar proteinsi

Entry informationi

Entry nameiO29536_ARCFU
AccessioniPrimary (citable) accession number: O29536
Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: October 25, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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