UniProtKB - O28821 (THSB_ARCFU)
Protein
Thermosome subunit beta
Gene
thsB
Organism
Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
Status
Functioni
Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.By similarity
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATP binding Source: UniProtKB-KW
- unfolded protein binding Source: InterPro
GO - Biological processi
- protein folding Source: InterPro
Keywordsi
Molecular function | Chaperone |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Thermosome subunit betaAlternative name(s): Chaperonin subunit beta Thermosome subunit 2 |
Gene namesi | Name:thsB Ordered Locus Names:AF_1451 |
Organismi | Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126) |
Taxonomic identifieri | 224325 [NCBI] |
Taxonomic lineagei | Archaea › Euryarchaeota › Archaeoglobi › Archaeoglobales › Archaeoglobaceae › Archaeoglobus › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000128382 | 1 – 545 | Thermosome subunit betaAdd BLAST | 545 |
Interactioni
Subunit structurei
Forms a Heterooligomeric complex of two stacked eight-membered rings.
By similarityGO - Molecular functioni
- unfolded protein binding Source: InterPro
Protein-protein interaction databases
STRINGi | 224325.AF_1451 |
Family & Domainsi
Sequence similaritiesi
Belongs to the TCP-1 chaperonin family.Curated
Phylogenomic databases
eggNOGi | arCOG01257, Archaea |
HOGENOMi | CLU_008891_7_3_2 |
OMAi | TGIQNMG |
OrthoDBi | 11742at2157 |
Family and domain databases
CDDi | cd03343, cpn60, 1 hit |
Gene3Di | 1.10.560.10, 1 hit 3.30.260.10, 1 hit 3.50.7.10, 1 hit |
InterProi | View protein in InterPro IPR017998, Chaperone_TCP-1 IPR002194, Chaperonin_TCP-1_CS IPR002423, Cpn60/TCP-1 IPR027409, GroEL-like_apical_dom_sf IPR027413, GROEL-like_equatorial_sf IPR027410, TCP-1-like_intermed_sf IPR012714, Thermosome_arc |
Pfami | View protein in Pfam PF00118, Cpn60_TCP1, 1 hit |
PRINTSi | PR00304, TCOMPLEXTCP1 |
SUPFAMi | SSF48592, SSF48592, 1 hit SSF52029, SSF52029, 1 hit SSF54849, SSF54849, 1 hit |
TIGRFAMsi | TIGR02339, thermosome_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00750, TCP1_1, 1 hit PS00751, TCP1_2, 1 hit PS00995, TCP1_3, 1 hit |
i Sequence
Sequence statusi: Complete.
O28821-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATLQGQPVL ILREGTQRTV GRDAQRMNIM AARVIAEAVR STLGPKGMDK
60 70 80 90 100
MLVDSLGDVV ITNDGVTILK EIDVEHPAAK MIIEVAKTQD NEVGDGTTTA
110 120 130 140 150
VVLAGELLKR AEELLDQEIH PAIIANGYRY AAEKALEILN EIAIPISKDD
160 170 180 190 200
DEILKKIATT AMTGKGAEVA IDKLAEIAVN AVKMIAEESN GQVEVNTDYI
210 220 230 240 250
KIEKRQGGSI EETELVDGIV LDKEVVHPGM PKRVENAKIL LLDSALEVKE
260 270 280 290 300
TEIDAKIRIT DPEKLQKFIE QEEAMLKEMV DKIVNAGANV VFCQKGIDDL
310 320 330 340 350
AQYYLAKAGV LAVRRVKKSD MEKLAKATGA KVLTDLRDIS SEDLGEAALV
360 370 380 390 400
EERKVGDEKM VFVTGCKNPK AVTILVRGGT EHVVEEIARG IEDAVRAVAC
410 420 430 440 450
AVEDGKVVVG AGAPEIEVSL KLREWAPSLG GREQLAVEAF ATALEIIPRT
460 470 480 490 500
LAENAGLDPI DVLVELKAAH EKGQKYAGVD VDTGKVVDMK ERGVFEPLRV
510 520 530 540
KTQAIGSATE VAVMILRIDD IIAAKGLEKE KGGGGEGGMP EMPEF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000782 Genomic DNA Translation: AAB89798.1 |
PIRi | B69431 |
RefSeqi | WP_010878948.1, NC_000917.1 |
Genome annotation databases
EnsemblBacteriai | AAB89798; AAB89798; AF_1451 |
GeneIDi | 24795063 |
KEGGi | afu:AF_1451 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000782 Genomic DNA Translation: AAB89798.1 |
PIRi | B69431 |
RefSeqi | WP_010878948.1, NC_000917.1 |
3D structure databases
SMRi | O28821 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 224325.AF_1451 |
Genome annotation databases
EnsemblBacteriai | AAB89798; AAB89798; AF_1451 |
GeneIDi | 24795063 |
KEGGi | afu:AF_1451 |
Phylogenomic databases
eggNOGi | arCOG01257, Archaea |
HOGENOMi | CLU_008891_7_3_2 |
OMAi | TGIQNMG |
OrthoDBi | 11742at2157 |
Family and domain databases
CDDi | cd03343, cpn60, 1 hit |
Gene3Di | 1.10.560.10, 1 hit 3.30.260.10, 1 hit 3.50.7.10, 1 hit |
InterProi | View protein in InterPro IPR017998, Chaperone_TCP-1 IPR002194, Chaperonin_TCP-1_CS IPR002423, Cpn60/TCP-1 IPR027409, GroEL-like_apical_dom_sf IPR027413, GROEL-like_equatorial_sf IPR027410, TCP-1-like_intermed_sf IPR012714, Thermosome_arc |
Pfami | View protein in Pfam PF00118, Cpn60_TCP1, 1 hit |
PRINTSi | PR00304, TCOMPLEXTCP1 |
SUPFAMi | SSF48592, SSF48592, 1 hit SSF52029, SSF52029, 1 hit SSF54849, SSF54849, 1 hit |
TIGRFAMsi | TIGR02339, thermosome_arch, 1 hit |
PROSITEi | View protein in PROSITE PS00750, TCP1_1, 1 hit PS00751, TCP1_2, 1 hit PS00995, TCP1_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | THSB_ARCFU | |
Accessioni | O28821Primary (citable) accession number: O28821 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1998 |
Last sequence update: | January 1, 1998 | |
Last modified: | April 7, 2021 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families