UniProtKB - O24855 (CYNT_HELPY)
Protein
Carbonic anhydrase
Gene
cynT
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Functioni
Catalytic activityi
- EC:4.2.1.1
Cofactori
Zn2+By similarityNote: Binds 1 zinc ion per subunit.By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 38 | ZincBy similarity | 1 | |
Metal bindingi | 40 | ZincBy similarity | 1 | |
Metal bindingi | 99 | ZincBy similarity | 1 | |
Metal bindingi | 102 | ZincBy similarity | 1 |
GO - Molecular functioni
- carbonate dehydratase activity Source: UniProtKB-EC
- zinc ion binding Source: InterPro
GO - Biological processi
- carbon utilization Source: InterPro
- cyanate catabolic process Source: GO_Central
Keywordsi
Molecular function | Lyase |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
BioCyci | HPY:HP0004-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:cynT Ordered Locus Names:HP_0004 |
Organismi | Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) |
Taxonomic identifieri | 85962 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000077461 | 1 – 221 | Carbonic anhydraseAdd BLAST | 221 |
Proteomic databases
PaxDbi | O24855 |
Interactioni
Protein-protein interaction databases
STRINGi | 85962.C694_00020 |
Chemistry databases
BindingDBi | O24855 |
Family & Domainsi
Sequence similaritiesi
Belongs to the beta-class carbonic anhydrase family.Curated
Phylogenomic databases
eggNOGi | COG0288, Bacteria |
OMAi | WHYIIET |
Family and domain databases
Gene3Di | 3.40.1050.10, 1 hit |
InterProi | View protein in InterPro IPR001765, Carbonic_anhydrase IPR015892, Carbonic_anhydrase_CS IPR036874, Carbonic_anhydrase_sf |
Pfami | View protein in Pfam PF00484, Pro_CA, 1 hit |
SMARTi | View protein in SMART SM00947, Pro_CA, 1 hit |
SUPFAMi | SSF53056, SSF53056, 1 hit |
PROSITEi | View protein in PROSITE PS00705, PROK_CO2_ANHYDRASE_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O24855-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKAFLGALEF QENEYEELKE LYESLKTKQK PHTLFISCVD SRVVPNLITG
60 70 80 90 100
TKPGELYVIC NMGNVNPPKT SYKESLSTIA SIEYAIAHVG VQNLIICGHS
110 120 130 140 150
DCGACGSVHL IHDETTKAKT PYIANWIQFL EPVKEELKNH PQFSNHFAKR
160 170 180 190 200
SWLTERLNAR LQLNNLLSYD FIQEKASKNE LKIFGWHYII ETGRIYNYNF
210 220
ESHFFEPIGE TIKQRKSHEN F
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000511 Genomic DNA Translation: AAD07077.1 |
PIRi | D64520 |
RefSeqi | NP_206806.1, NC_000915.1 WP_000642977.1, NC_018939.1 |
Genome annotation databases
EnsemblBacteriai | AAD07077; AAD07077; HP_0004 |
KEGGi | heo:C694_00020 hpy:HP0004 |
PATRICi | fig|85962.47.peg.4 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000511 Genomic DNA Translation: AAD07077.1 |
PIRi | D64520 |
RefSeqi | NP_206806.1, NC_000915.1 WP_000642977.1, NC_018939.1 |
3D structure databases
SMRi | O24855 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 85962.C694_00020 |
Chemistry databases
BindingDBi | O24855 |
ChEMBLi | CHEMBL4211 |
DrugCentrali | O24855 |
Proteomic databases
PaxDbi | O24855 |
Genome annotation databases
EnsemblBacteriai | AAD07077; AAD07077; HP_0004 |
KEGGi | heo:C694_00020 hpy:HP0004 |
PATRICi | fig|85962.47.peg.4 |
Phylogenomic databases
eggNOGi | COG0288, Bacteria |
OMAi | WHYIIET |
Enzyme and pathway databases
BioCyci | HPY:HP0004-MONOMER |
Family and domain databases
Gene3Di | 3.40.1050.10, 1 hit |
InterProi | View protein in InterPro IPR001765, Carbonic_anhydrase IPR015892, Carbonic_anhydrase_CS IPR036874, Carbonic_anhydrase_sf |
Pfami | View protein in Pfam PF00484, Pro_CA, 1 hit |
SMARTi | View protein in SMART SM00947, Pro_CA, 1 hit |
SUPFAMi | SSF53056, SSF53056, 1 hit |
PROSITEi | View protein in PROSITE PS00705, PROK_CO2_ANHYDRASE_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CYNT_HELPY | |
Accessioni | O24855Primary (citable) accession number: O24855 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1999 |
Last sequence update: | January 1, 1998 | |
Last modified: | December 2, 2020 | |
This is version 105 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families