UniProtKB - O24390 (O24390_SOLTU)
Protein
Nitrate reductase
Gene
StNR2
Organism
Solanum tuberosum (Potato)
Status
Functioni
Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.UniRule annotationARBA annotation
Catalytic activityi
- EC:1.7.1.1ARBA annotation
Cofactori
Protein has several cofactor binding sites:- FADARBA annotation
- Mo-molybdopterinUniRule annotationNote: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.UniRule annotation
- hemeARBA annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 188 | MolybdenumUniRule annotation | 1 |
GO - Molecular functioni
- heme binding Source: InterPro
- molybdenum ion binding Source: InterPro
- molybdopterin cofactor binding Source: InterPro
- nitrate reductase (NADH) activity Source: UniProtKB-EC
- nitrate reductase (NADPH) activity Source: InterPro
GO - Biological processi
- nitrate assimilation Source: UniProtKB-KW
- nitric oxide biosynthetic process Source: InterPro
Keywordsi
Molecular function | OxidoreductaseImportedARBA annotation |
Biological process | Nitrate assimilationUniRule annotationARBA annotation |
Ligand | FADARBA annotation, Flavoprotein, HemeARBA annotation, Iron, Metal-binding, MolybdenumUniRule annotationARBA annotation, NADARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Nitrate reductaseUniRule annotation |
Gene namesi | Name:StNR2Imported |
Organismi | Solanum tuberosum (Potato)Imported |
Taxonomic identifieri | 4113 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum |
Interactioni
Subunit structurei
Homodimer.
ARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 536 – 611 | Cytochrome b5 heme-bindingInterPro annotationAdd BLAST | 76 | |
Domaini | 654 – 766 | FAD-binding FR-typeInterPro annotationAdd BLAST | 113 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 49 | DisorderedSequence analysisAdd BLAST | 49 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 35 – 49 | PolarSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Phylogenomic databases
OMAi | ALMPGGW |
Family and domain databases
Gene3Di | 3.10.120.10, 1 hit 3.40.50.80, 1 hit 3.90.420.10, 1 hit |
InterProi | View protein in InterPro IPR001834, CBR-like IPR008333, Cbr1-like_FAD-bd_dom IPR001199, Cyt_B5-like_heme/steroid-bd IPR036400, Cyt_B5-like_heme/steroid_sf IPR018506, Cyt_B5_heme-BS IPR017927, FAD-bd_FR_type IPR001709, Flavoprot_Pyr_Nucl_cyt_Rdtase IPR039261, FNR_nucleotide-bd IPR014756, Ig_E-set IPR005066, MoCF_OxRdtse_dimer IPR008335, Mopterin_OxRdtase_euk IPR012137, Nitr_rd_NADH IPR001433, OxRdtase_FAD/NAD-bd IPR000572, OxRdtase_Mopterin-bd_dom IPR036374, OxRdtase_Mopterin-bd_sf IPR022407, OxRdtase_Mopterin_BS IPR017938, Riboflavin_synthase-like_b-brl |
Pfami | View protein in Pfam PF00173, Cyt-b5, 1 hit PF00970, FAD_binding_6, 1 hit PF03404, Mo-co_dimer, 1 hit PF00175, NAD_binding_1, 1 hit PF00174, Oxidored_molyb, 1 hit |
PIRSFi | PIRSF000233, Nitr_rd_NADH, 1 hit |
PRINTSi | PR00406, CYTB5RDTASE PR00363, CYTOCHROMEB5 PR00407, EUMOPTERIN PR00371, FPNCR |
SMARTi | View protein in SMART SM01117, Cyt-b5, 1 hit |
SUPFAMi | SSF52343, SSF52343, 1 hit SSF55856, SSF55856, 1 hit SSF56524, SSF56524, 1 hit SSF63380, SSF63380, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS00191, CYTOCHROME_B5_1, 1 hit PS50255, CYTOCHROME_B5_2, 1 hit PS51384, FAD_FR, 1 hit PS00559, MOLYBDOPTERIN_EUK, 1 hit |
i Sequence
Sequence statusi: Complete.
O24390-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAASVENRQF THLEPGLSGV GRTFKPRPDS PVRGCNFPPS SNHELPFQKQ
60 70 80 90 100
QNLPIYLDYS SSEDEDDDDE KNEYVQMIKK GKTELEPSIH DTRDEGTADN
110 120 130 140 150
WIQRNFSLIR LTGKHPFNSE PPLARLMHHG FITPVPLHYV RNHGPVPKAS
160 170 180 190 200
WADWSVEVTG LVKRPMKFTM DQLVNEFPSR ELPVTLVCAG NRRKEQNMVK
210 220 230 240 250
QTIGFNWGAA AVSTTVWRGV PLRPLLKRCG VHSKKKGALN ICFEGSDVLP
260 270 280 290 300
GGGGSKYGTS IKNEFAMDPS RDIIVAYMQN GEMLSPDHGF PVRMIIPGFI
310 320 330 340 350
GGRMVKWPKR IVVTTQESES YYHYKDNRVL PPHVELELAN AEAWWYKPEY
360 370 380 390 400
IINELNINSV ITTPSHEEIL PINAWTTQRP YTLRGYAYPG GGKKVTRVEV
410 420 430 440 450
TLDGGETWSV CTLDHPEKPT KYGKYWCWCF WSLEVEVLDL LRAKEIAVRA
460 470 480 490 500
IDETHNTQPE KLIWNVMGMM NNCWFRVKMK CVKPHKGEIG IVFEHPTQPG
510 520 530 540 550
NQSGGWMAKE RHLEISAVAP PTLKKSISTP FMNTASKMYS MSEVRKHNSS
560 570 580 590 600
DSAWIIVHGH IYDASRFLKD HPGGVDSILI NAGTDCTEEF DAIHSDKAKK
610 620 630 640 650
LLEDFRIGEL ITTGYTSDSS PNTSVHGSSS ISSFLAPIKE LVQTPTRSVA
660 670 680 690 700
LIPREKIPCK LVDKQSISHD VRKFKFALPS EDQVLGLPVG KHIFLCATVD
710 720 730 740 750
DKLCMRAYTP TSTVDEVGFF ELVVKIYFKG VHPKFPNGGQ MSQHLDSLPI
760 770 780 790 800
GAFLDVKGPL GHIEYQGKGN FLVHGKQKFP KKLAMIAGGT GITPVYQVIE
810 820 830 840 850
SILKDPEDDT EMYVVYANRT EDDILLKEEL DAWAEQIPDR VKVWYVVQES
860 870 880 890 900
ITEGWKYSTG FVTEAILREH IPQPSHTTLA LACGPPPMIQ FAINPNLEKM
910
GYDIKEELLV F
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U76701 mRNA Translation: AAB18985.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U76701 mRNA Translation: AAB18985.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Phylogenomic databases
OMAi | ALMPGGW |
Gene expression databases
ExpressionAtlasi | O24390, baseline |
Family and domain databases
Gene3Di | 3.10.120.10, 1 hit 3.40.50.80, 1 hit 3.90.420.10, 1 hit |
InterProi | View protein in InterPro IPR001834, CBR-like IPR008333, Cbr1-like_FAD-bd_dom IPR001199, Cyt_B5-like_heme/steroid-bd IPR036400, Cyt_B5-like_heme/steroid_sf IPR018506, Cyt_B5_heme-BS IPR017927, FAD-bd_FR_type IPR001709, Flavoprot_Pyr_Nucl_cyt_Rdtase IPR039261, FNR_nucleotide-bd IPR014756, Ig_E-set IPR005066, MoCF_OxRdtse_dimer IPR008335, Mopterin_OxRdtase_euk IPR012137, Nitr_rd_NADH IPR001433, OxRdtase_FAD/NAD-bd IPR000572, OxRdtase_Mopterin-bd_dom IPR036374, OxRdtase_Mopterin-bd_sf IPR022407, OxRdtase_Mopterin_BS IPR017938, Riboflavin_synthase-like_b-brl |
Pfami | View protein in Pfam PF00173, Cyt-b5, 1 hit PF00970, FAD_binding_6, 1 hit PF03404, Mo-co_dimer, 1 hit PF00175, NAD_binding_1, 1 hit PF00174, Oxidored_molyb, 1 hit |
PIRSFi | PIRSF000233, Nitr_rd_NADH, 1 hit |
PRINTSi | PR00406, CYTB5RDTASE PR00363, CYTOCHROMEB5 PR00407, EUMOPTERIN PR00371, FPNCR |
SMARTi | View protein in SMART SM01117, Cyt-b5, 1 hit |
SUPFAMi | SSF52343, SSF52343, 1 hit SSF55856, SSF55856, 1 hit SSF56524, SSF56524, 1 hit SSF63380, SSF63380, 1 hit SSF81296, SSF81296, 1 hit |
PROSITEi | View protein in PROSITE PS00191, CYTOCHROME_B5_1, 1 hit PS50255, CYTOCHROME_B5_2, 1 hit PS51384, FAD_FR, 1 hit PS00559, MOLYBDOPTERIN_EUK, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | O24390_SOLTU | |
Accessioni | O24390Primary (citable) accession number: O24390 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 1, 1998 |
Last sequence update: | January 1, 1998 | |
Last modified: | April 7, 2021 | |
This is version 118 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |