UniProtKB - O24296 (GPX1_PEA)
Protein
Phospholipid hydroperoxide glutathione peroxidase, chloroplastic
Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Functioni
Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione.By similarity
Catalytic activityi
- a hydroperoxy polyunsaturated fatty acid + 2 glutathione = a hydroxy polyunsaturated fatty acid + glutathione disulfide + H2OBy similarityEC:1.11.1.12By similarity
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 111 | By similarity | 1 |
GO - Molecular functioni
- glutathione peroxidase activity Source: InterPro
- phospholipid-hydroperoxide glutathione peroxidase activity Source: UniProtKB-EC
GO - Biological processi
- response to oxidative stress Source: InterPro
Keywordsi
Molecular function | Oxidoreductase, Peroxidase |
Protein family/group databases
PeroxiBasei | 2897, PsGPx01 |
Names & Taxonomyi
Protein namesi | Recommended name: Phospholipid hydroperoxide glutathione peroxidase, chloroplastic (EC:1.11.1.12)Short name: PHGPx |
Organismi | Pisum sativum (Garden pea) |
Taxonomic identifieri | 3888 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Fabales › Fabaceae › Papilionoideae › 50 kb inversion clade › NPAAA clade › Hologalegina › IRL clade › Fabeae › Pisum |
Subcellular locationi
Chloroplast
Chloroplast
- chloroplast stroma Source: UniProtKB-SubCell
Keywords - Cellular componenti
Chloroplast, PlastidPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 64 | ChloroplastSequence analysisAdd BLAST | 64 | |
ChainiPRO_0000013087 | 65 – 236 | Phospholipid hydroperoxide glutathione peroxidase, chloroplasticAdd BLAST | 172 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glutathione peroxidase family.Curated
Keywords - Domaini
Transit peptideFamily and domain databases
CDDi | cd00340, GSH_Peroxidase, 1 hit |
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR000889, Glutathione_peroxidase IPR029759, GPX_AS IPR029760, GPX_CS IPR036249, Thioredoxin-like_sf |
PANTHERi | PTHR11592, PTHR11592, 1 hit |
Pfami | View protein in Pfam PF00255, GSHPx, 1 hit |
PRINTSi | PR01011, GLUTPROXDASE |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS00460, GLUTATHIONE_PEROXID_1, 1 hit PS00763, GLUTATHIONE_PEROXID_2, 1 hit PS51355, GLUTATHIONE_PEROXID_3, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O24296-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASMAFSTTF FTPLRDFNQP RTNSTPSTSL PFTKSSIASS KSPFFQLGFS
60 70 80 90 100
QQASSNFPIV PSKTRSFSVN AKAIKDKTIY DFTVKDIDKK DVSLSKFKGK
110 120 130 140 150
VLLIVNVASR CGLTSSNYTE LSHLYENFKN KGLEVLAFPC NQFGMQEPGS
160 170 180 190 200
NEEIKQFACT KFKAEFPIFD KVDVNGPFTA PVYQFLKSSS GGFFGDIVKW
210 220 230
NFEKFLVDKN GKVVERYPPT TSPFQIEKDI QKLLAA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ000508 mRNA Translation: CAA04142.1 |
PIRi | T06462 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ000508 mRNA Translation: CAA04142.1 |
PIRi | T06462 |
3D structure databases
SMRi | O24296 |
ModBasei | Search... |
Protein family/group databases
PeroxiBasei | 2897, PsGPx01 |
Family and domain databases
CDDi | cd00340, GSH_Peroxidase, 1 hit |
Gene3Di | 3.40.30.10, 1 hit |
InterProi | View protein in InterPro IPR000889, Glutathione_peroxidase IPR029759, GPX_AS IPR029760, GPX_CS IPR036249, Thioredoxin-like_sf |
PANTHERi | PTHR11592, PTHR11592, 1 hit |
Pfami | View protein in Pfam PF00255, GSHPx, 1 hit |
PRINTSi | PR01011, GLUTPROXDASE |
SUPFAMi | SSF52833, SSF52833, 1 hit |
PROSITEi | View protein in PROSITE PS00460, GLUTATHIONE_PEROXID_1, 1 hit PS00763, GLUTATHIONE_PEROXID_2, 1 hit PS51355, GLUTATHIONE_PEROXID_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | GPX1_PEA | |
Accessioni | O24296Primary (citable) accession number: O24296 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 27, 2002 |
Last sequence update: | January 1, 1998 | |
Last modified: | October 7, 2020 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |