UniProtKB - O23729 (CHS3_BROFI)
Protein
Chalcone synthase 3
Gene
CHS3
Organism
Bromheadia finlaysoniana (Orchid)
Status
Functioni
The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.
Catalytic activityi
- 4-coumaroyl-CoA + 2 H+ + 3 malonyl-CoA = 2',4,4',6'-tetrahydroxychalcone + 3 CO2 + 4 CoAPROSITE-ProRule annotationEC:2.3.1.74PROSITE-ProRule annotation
: flavonoid biosynthesis Pathwayi
This protein is involved in the pathway flavonoid biosynthesis, which is part of Secondary metabolite biosynthesis.View all proteins of this organism that are known to be involved in the pathway flavonoid biosynthesis and in Secondary metabolite biosynthesis.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 165 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- naringenin-chalcone synthase activity Source: UniProtKB-EC
GO - Biological processi
- flavonoid biosynthetic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Acyltransferase, Transferase |
Biological process | Flavonoid biosynthesis |
Enzyme and pathway databases
UniPathwayi | UPA00154 |
Names & Taxonomyi
Protein namesi | Recommended name: Chalcone synthase 3 (EC:2.3.1.74)Alternative name(s): Naringenin-chalcone synthase 3 |
Gene namesi | Name:CHS3 |
Organismi | Bromheadia finlaysoniana (Orchid) |
Taxonomic identifieri | 41205 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Asparagales › Orchidaceae › Epidendroideae › Vandeae › Adrorhizinae › Bromheadia |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000215956 | 1 – 394 | Chalcone synthase 3Add BLAST | 394 |
Proteomic databases
PRIDEi | O23729 |
Family & Domainsi
Sequence similaritiesi
Family and domain databases
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR012328, Chalcone/stilbene_synth_C IPR018088, Chalcone/stilbene_synthase_AS IPR001099, Chalcone/stilbene_synthase_N IPR011141, Polyketide_synthase_type-III IPR016039, Thiolase-like |
PANTHERi | PTHR11877, PTHR11877, 1 hit |
Pfami | View protein in Pfam PF02797, Chal_sti_synt_C, 1 hit PF00195, Chal_sti_synt_N, 1 hit |
PIRSFi | PIRSF000451, PKS_III, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
PROSITEi | View protein in PROSITE PS00441, CHALCONE_SYNTH, 1 hit |
i Sequence
Sequence statusi: Complete.
O23729-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPAMEEIRQ AQRAEGPAAV LAIGTSTPPN ALYQADYPDY YFRITKSEHL
60 70 80 90 100
TELKEKFKRM CDKSMIKKRY MYLTEEILKE NPNICAFMAP SLDARQDIVV
110 120 130 140 150
TEVPKLAKEA AVRAIKEWGH PKSRITHLIF CTTSGIDMPG ADYQLTRLLG
160 170 180 190 200
LRPSVNRFML YQQGCFAGGT VLRLAKDLAE NNAGARVLVV CSEITAVTFR
210 220 230 240 250
GPSESHLDSL VGQALFGDGA AAIIVGSDPD SATERPLFQL VSASQTILPE
260 270 280 290 300
SEGAIDGHLR EIGLTFHLLK DVPGLISKNI QKCLLDAFKP LGVHDWNSIF
310 320 330 340 350
WIAHPGGPAI LDQVEIKLGL KAEKLAASRN VLAEYGNMSS ACVLFILDEM
360 370 380 390
RRRSAEAGQA TTGEGLEWGV LFGFGPGLTV ETIVLRSVPI AGAE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF007097 mRNA Translation: AAB62874.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF007097 mRNA Translation: AAB62874.1 |
3D structure databases
SMRi | O23729 |
ModBasei | Search... |
Proteomic databases
PRIDEi | O23729 |
Enzyme and pathway databases
UniPathwayi | UPA00154 |
Family and domain databases
Gene3Di | 3.40.47.10, 2 hits |
InterProi | View protein in InterPro IPR012328, Chalcone/stilbene_synth_C IPR018088, Chalcone/stilbene_synthase_AS IPR001099, Chalcone/stilbene_synthase_N IPR011141, Polyketide_synthase_type-III IPR016039, Thiolase-like |
PANTHERi | PTHR11877, PTHR11877, 1 hit |
Pfami | View protein in Pfam PF02797, Chal_sti_synt_C, 1 hit PF00195, Chal_sti_synt_N, 1 hit |
PIRSFi | PIRSF000451, PKS_III, 1 hit |
SUPFAMi | SSF53901, SSF53901, 2 hits |
PROSITEi | View protein in PROSITE PS00441, CHALCONE_SYNTH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CHS3_BROFI | |
Accessioni | O23729Primary (citable) accession number: O23729 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1999 |
Last sequence update: | January 1, 1998 | |
Last modified: | December 11, 2019 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families