UniProtKB - O22768 (UNE12_ARATH)
Protein
Transcription factor UNE12
Gene
UNE12
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Required for ovule fertilization.1 Publication
GO - Molecular functioni
- DNA-binding transcription factor activity Source: TAIR
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein dimerization activity Source: InterPro
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- double fertilization forming a zygote and endosperm Source: TAIR
- multicellular organism development Source: UniProtKB-KW
- regulation of defense response Source: TAIR
- regulation of transcription, DNA-templated Source: TAIR
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | Developmental protein, DNA-binding |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription factor UNE12Alternative name(s): Basic helix-loop-helix protein 59 Short name: AtbHLH59 Short name: bHLH 59 Protein UNFERTILIZED EMBRYO SAC 12 Transcription factor EN 93 bHLH transcription factor bHLH059 |
Gene namesi | Name:UNE12 Synonyms:BHLH59, EN93 Ordered Locus Names:At4g02590 ORF Names:T10P11.13 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT4G02590 |
TAIRi | locus:2132303, AT4G02590 |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000358857 | 1 – 310 | Transcription factor UNE12Add BLAST | 310 |
Proteomic databases
PaxDbi | O22768 |
PRIDEi | O22768 |
ProteomicsDBi | 245318 [O22768-1] |
Expressioni
Tissue specificityi
Expressed constitutively in roots, leaves, stems, and flowers.1 Publication
Gene expression databases
ExpressionAtlasi | O22768, baseline and differential |
Genevisiblei | O22768, AT |
Interactioni
Subunit structurei
Homodimer.
CuratedBinary interactionsi
Hide detailsO22768
With | #Exp. | IntAct |
---|---|---|
At3g18240 [A0A384L363] | 3 | EBI-3133156,EBI-25511057 |
EBF1 [Q9SKK0] | 3 | EBI-3133156,EBI-401198 |
KNAT1 [P46639] | 3 | EBI-3133156,EBI-530486 |
GO - Molecular functioni
- protein dimerization activity Source: InterPro
Protein-protein interaction databases
BioGRIDi | 13415, 32 interactors |
IntActi | O22768, 34 interactors |
STRINGi | 3702.AT4G02590.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 152 – 201 | bHLHPROSITE-ProRule annotationAdd BLAST | 50 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 36 – 104 | Gly-richAdd BLAST | 69 |
Phylogenomic databases
eggNOGi | ENOG502QPM5, Eukaryota |
InParanoidi | O22768 |
PhylomeDBi | O22768 |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
s (2)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: O22768-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MASNNPHDNL SDQTPSDDFF EQILGLPNFS ASSAAGLSGV DGGLGGGAPP
60 70 80 90 100
MMLQLGSGEE GSHMGGLGGS GPTGFHNQMF PLGLSLDQGK GPGFLRPEGG
110 120 130 140 150
HGSGKRFSDD VVDNRCSSMK PVFHGQPMQQ PPPSAPHQPT SIRPRVRARR
160 170 180 190 200
GQATDPHSIA ERLRRERIAE RIRALQELVP TVNKTDRAAM IDEIVDYVKF
210 220 230 240 250
LRLQVKVLSM SRLGGAGAVA PLVTDMPLSS SVEDETGEGG RTPQPAWEKW
260 270 280 290 300
SNDGTERQVA KLMEENVGAA MQLLQSKALC MMPISLAMAI YHSQPPDTSS
310
VVKPENNPPQ
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 216 | A → V in AAM65759 (Ref. 5) Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_036114 | 1 – 63 | Missing in isoform 2. CuratedAdd BLAST | 63 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF488592 mRNA Translation: AAM10948.1 AC002330 Genomic DNA Translation: AAC78259.1 AL161494 Genomic DNA Translation: CAB80752.1 CP002687 Genomic DNA Translation: AEE82199.1 CP002687 Genomic DNA Translation: AEE82200.1 CP002687 Genomic DNA Translation: AEE82201.1 AF367328 mRNA Translation: AAK32915.1 AY143951 mRNA Translation: AAN28890.1 AY088218 mRNA Translation: AAM65759.1 |
PIRi | T01090 |
RefSeqi | NP_001031577.1, NM_001036500.2 [O22768-1] NP_001118919.1, NM_001125447.1 [O22768-2] NP_567245.1, NM_116493.3 [O22768-1] |
Genome annotation databases
EnsemblPlantsi | AT4G02590.1; AT4G02590.1; AT4G02590 [O22768-1] AT4G02590.2; AT4G02590.2; AT4G02590 [O22768-1] AT4G02590.3; AT4G02590.3; AT4G02590 [O22768-2] |
GeneIDi | 828126 |
Gramenei | AT4G02590.1; AT4G02590.1; AT4G02590 [O22768-1] AT4G02590.2; AT4G02590.2; AT4G02590 [O22768-1] AT4G02590.3; AT4G02590.3; AT4G02590 [O22768-2] |
KEGGi | ath:AT4G02590 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF488592 mRNA Translation: AAM10948.1 AC002330 Genomic DNA Translation: AAC78259.1 AL161494 Genomic DNA Translation: CAB80752.1 CP002687 Genomic DNA Translation: AEE82199.1 CP002687 Genomic DNA Translation: AEE82200.1 CP002687 Genomic DNA Translation: AEE82201.1 AF367328 mRNA Translation: AAK32915.1 AY143951 mRNA Translation: AAN28890.1 AY088218 mRNA Translation: AAM65759.1 |
PIRi | T01090 |
RefSeqi | NP_001031577.1, NM_001036500.2 [O22768-1] NP_001118919.1, NM_001125447.1 [O22768-2] NP_567245.1, NM_116493.3 [O22768-1] |
3D structure databases
SMRi | O22768 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 13415, 32 interactors |
IntActi | O22768, 34 interactors |
STRINGi | 3702.AT4G02590.1 |
Proteomic databases
PaxDbi | O22768 |
PRIDEi | O22768 |
ProteomicsDBi | 245318 [O22768-1] |
Genome annotation databases
EnsemblPlantsi | AT4G02590.1; AT4G02590.1; AT4G02590 [O22768-1] AT4G02590.2; AT4G02590.2; AT4G02590 [O22768-1] AT4G02590.3; AT4G02590.3; AT4G02590 [O22768-2] |
GeneIDi | 828126 |
Gramenei | AT4G02590.1; AT4G02590.1; AT4G02590 [O22768-1] AT4G02590.2; AT4G02590.2; AT4G02590 [O22768-1] AT4G02590.3; AT4G02590.3; AT4G02590 [O22768-2] |
KEGGi | ath:AT4G02590 |
Organism-specific databases
Araporti | AT4G02590 |
TAIRi | locus:2132303, AT4G02590 |
Phylogenomic databases
eggNOGi | ENOG502QPM5, Eukaryota |
InParanoidi | O22768 |
PhylomeDBi | O22768 |
Miscellaneous databases
PROi | PR:O22768 |
Gene expression databases
ExpressionAtlasi | O22768, baseline and differential |
Genevisiblei | O22768, AT |
Family and domain databases
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR036638, HLH_DNA-bd_sf |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | UNE12_ARATH | |
Accessioni | O22768Primary (citable) accession number: O22768 Secondary accession number(s): B3H4J4, Q8L9U3, Q8S3E3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 16, 2008 |
Last sequence update: | January 1, 1999 | |
Last modified: | April 7, 2021 | |
This is version 140 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names