UniProtKB - O22299 (LET6_SOLLC)
Protein
Homeobox protein knotted-1-like LET6
Gene
LET6
Organism
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
Status
Functioni
May have a role to play in formative events in ovule and embryo morphogenesis. Probably binds to the DNA sequence 5'-TGAC-3'.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 258 – 321 | Homeobox; TALE-typePROSITE-ProRule annotationAdd BLAST | 64 |
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein homodimerization activity Source: EnsemblPlants
- RNA binding Source: EnsemblPlants
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- carpel development Source: EnsemblPlants
- floral meristem determinacy Source: EnsemblPlants
- regulation of meristem structural organization Source: EnsemblPlants
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Homeobox protein knotted-1-like LET6 |
Gene namesi | Name:LET6 |
Organismi | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
Taxonomic identifieri | 4081 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum › Solanum subgen. Lycopersicon |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus Curated
Cytoskeleton
- microtubule cytoskeleton Source: EnsemblPlants
Endosome
- endosome Source: EnsemblPlants
Nucleus
- nuclear chromatin Source: GO_Central
Plasma Membrane
- plasma membrane Source: EnsemblPlants
Other locations
- plasmodesma Source: EnsemblPlants
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000048973 | 1 – 355 | Homeobox protein knotted-1-like LET6Add BLAST | 355 |
Proteomic databases
PaxDbi | O22299 |
PRIDEi | O22299 |
Expressioni
Tissue specificityi
Expressed in developing lateral organs and developing ovaries in flowers.
Gene expression databases
ExpressionAtlasi | O22299, baseline |
Interactioni
GO - Molecular functioni
- protein homodimerization activity Source: EnsemblPlants
Protein-protein interaction databases
STRINGi | 4081.Solyc02g081120.2.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 237 – 257 | ELKPROSITE-ProRule annotationAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 24 – 33 | Poly-Asn | 10 | |
Compositional biasi | 47 – 51 | Poly-Met | 5 | |
Compositional biasi | 52 – 56 | Poly-Pro | 5 | |
Compositional biasi | 60 – 63 | Poly-Asn | 4 | |
Compositional biasi | 79 – 84 | Poly-Asn | 6 | |
Compositional biasi | 91 – 95 | Poly-Ser | 5 | |
Compositional biasi | 142 – 146 | Poly-Ser | 5 |
Sequence similaritiesi
Belongs to the TALE/KNOX homeobox family.PROSITE-ProRule annotation
Keywords - Domaini
HomeoboxPhylogenomic databases
eggNOGi | KOG0773, Eukaryota |
InParanoidi | O22299 |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR005539, ELK_dom IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR008422, Homeobox_KN_domain IPR005540, KNOX1 IPR005541, KNOX2 |
Pfami | View protein in Pfam PF03789, ELK, 1 hit PF05920, Homeobox_KN, 1 hit PF03790, KNOX1, 1 hit PF03791, KNOX2, 1 hit |
SMARTi | View protein in SMART SM01188, ELK, 1 hit SM00389, HOX, 1 hit SM01255, KNOX1, 1 hit SM01256, KNOX2, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51213, ELK, 1 hit PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O22299-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEGGSSGNTS TSCLMMMGYG DHENNNNNNG NGNGNGNGNV TICAPPMMMM
60 70 80 90 100
MPPPPPSLTN NNNAETSNNN ILFLPFMDNN NNNNPQEDNN SSSSSIKSKI
110 120 130 140 150
MAHPHYHRLL TAYLNCQKIG APPEVVARLE EICATSATMG RSSSSSGGGI
160 170 180 190 200
IGEDPALDQF MEAYCEMLTK YEQELSKPFK EAMVFLSRIE CQFKALTLAP
210 220 230 240 250
NSSHESALGE AMDRNGSSDE EVDVNNSFID PQAEDRELKG QLLRKYSGYL
260 270 280 290 300
GSLKQEFMKK RKKGKLPKEA RQQLVDWWLR HIKWPYPSES QKLALAESTG
310 320 330 340 350
LDQKQINNWF INQRKRHWKP SEDMQFVVMD AAHPHYYMDN VLANHFPMDM
TPSLL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF000141 mRNA Translation: AAC49917.1 |
PIRi | T04317 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF000141 mRNA Translation: AAC49917.1 |
PIRi | T04317 |
3D structure databases
SMRi | O22299 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4081.Solyc02g081120.2.1 |
Proteomic databases
PaxDbi | O22299 |
PRIDEi | O22299 |
Phylogenomic databases
eggNOGi | KOG0773, Eukaryota |
InParanoidi | O22299 |
Gene expression databases
ExpressionAtlasi | O22299, baseline |
Family and domain databases
CDDi | cd00086, homeodomain, 1 hit |
InterProi | View protein in InterPro IPR005539, ELK_dom IPR009057, Homeobox-like_sf IPR017970, Homeobox_CS IPR001356, Homeobox_dom IPR008422, Homeobox_KN_domain IPR005540, KNOX1 IPR005541, KNOX2 |
Pfami | View protein in Pfam PF03789, ELK, 1 hit PF05920, Homeobox_KN, 1 hit PF03790, KNOX1, 1 hit PF03791, KNOX2, 1 hit |
SMARTi | View protein in SMART SM01188, ELK, 1 hit SM00389, HOX, 1 hit SM01255, KNOX1, 1 hit SM01256, KNOX2, 1 hit |
SUPFAMi | SSF46689, SSF46689, 1 hit |
PROSITEi | View protein in PROSITE PS51213, ELK, 1 hit PS00027, HOMEOBOX_1, 1 hit PS50071, HOMEOBOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | LET6_SOLLC | |
Accessioni | O22299Primary (citable) accession number: O22299 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1999 |
Last sequence update: | January 1, 1998 | |
Last modified: | December 2, 2020 | |
This is version 109 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families