UniProtKB - O22187 (Y2232_ARATH)
Protein
Probable receptor-like protein kinase At2g23200
Gene
At2g23200
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 516 | ATPPROSITE-ProRule annotation | 1 | |
Active sitei | 613 | Proton acceptorPROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 494 – 502 | ATPPROSITE-ProRule annotation | 9 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- protein kinase activity Source: GO_Central
- protein serine/threonine kinase activity Source: UniProtKB-KW
GO - Biological processi
- protein autophosphorylation Source: GO_Central
Keywordsi
Molecular function | Kinase, Serine/threonine-protein kinase, Transferase |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Ordered Locus Names:At2g23200 ORF Names:T20D16.17 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G23200 |
TAIRi | locus:2058636, AT2G23200 |
Subcellular locationi
Other locations
- Membrane Curated; Single-pass type I membrane protein Curated
Plasma Membrane
- plasma membrane Source: GO_Central
Vacuole
- vacuole Source: TAIR
Other locations
- integral component of membrane Source: UniProtKB-KW
- plasmodesma Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 29 – 405 | ExtracellularSequence analysisAdd BLAST | 377 | |
Transmembranei | 406 – 426 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 427 – 834 | CytoplasmicSequence analysisAdd BLAST | 408 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 28 | Sequence analysisAdd BLAST | 28 | |
ChainiPRO_0000386553 | 29 – 834 | Probable receptor-like protein kinase At2g23200Add BLAST | 806 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 61 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 149 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 221 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 246 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 277 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 289 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 314 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 352 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 361 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 394 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | O22187 |
PRIDEi | O22187 |
ProteomicsDBi | 243060 |
PTM databases
iPTMneti | O22187 |
Expressioni
Gene expression databases
ExpressionAtlasi | O22187, baseline and differential |
Genevisiblei | O22187, AT |
Interactioni
Protein-protein interaction databases
BioGRIDi | 2205, 2 interactors |
IntActi | O22187, 2 interactors |
STRINGi | 3702.AT2G23200.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 488 – 761 | Protein kinasePROSITE-ProRule annotationAdd BLAST | 274 |
Sequence similaritiesi
Keywords - Domaini
Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1187, Eukaryota |
HOGENOMi | CLU_000288_42_1_1 |
InParanoidi | O22187 |
OMAi | VNIDEGR |
OrthoDBi | 684563at2759 |
PhylomeDBi | O22187 |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR024788, Malectin-like_Carb-bd_dom IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF12819, Malectin_like, 1 hit PF07714, PK_Tyr_Ser-Thr, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O22187-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENFCFQDSV SLFITIMVLV LLPRLSLSDT STYTRPENFY VNCGSDSNVF
60 70 80 90 100
YGGQTFVGDT NSSTNSVSFT NKGTEVINDQ SSVAPEIYRT VRIFRHPSSY
110 120 130 140 150
KFKLDSLGLH FVRLHFSVVF SRADLLTARF TVSATSGSNH HLKSFSPQNL
160 170 180 190 200
TNTPRVEEFL LMMNSLEFEI RFVPDHSSLA LINAIEVFSA PDDLEIPSAS
210 220 230 240 250
DKNLHTIYRL NVGGEKITPD NDTLGRTWLP DDDDFLYRKD SARNINSTQT
260 270 280 290 300
PNYVGGLSSA TDSTAPDFVY KTAKAMNRSS NEQVGMLMNV TWSFKVKSNH
310 320 330 340 350
RHFIRIHFSD ILSNLSNSDS DFYLFVNGYW RVDVKPSEQP RLASPFFKDV
360 370 380 390 400
VNVSDGSGLL NISIGTKEAN KDAGFLNGLE MMEVLSKSGS DYSNRSSSRV
410 420 430 440 450
HIITGCAVAA AAASALVFSL LFMVFLKRRR SKKTKPEVEG TVWSPLPLHR
460 470 480 490 500
GGSSDNRPIS QYHNSPLRNL HLGLTIPFTD ILSATNNFDE QLLIGKGGFG
510 520 530 540 550
YVYKAILPDG TKAAIKRGKT GSGQGILEFQ TEIQVLSRIR HRHLVSLTGY
560 570 580 590 600
CEENSEMILV YEFMEKGTLK EHLYGSNLPS LTWKQRLEIC IGAARGLDYL
610 620 630 640 650
HSSGSEGAII HRDVKSTNIL LDEHNIAKVA DFGLSKIHNQ DESNISINIK
660 670 680 690 700
GTFGYLDPEY LQTHKLTEKS DVYAFGVVLL EVLFARPAID PYLPHEEVNL
710 720 730 740 750
SEWVMFCKSK GTIDEILDPS LIGQIETNSL KKFMEIAEKC LKEYGDERPS
760 770 780 790 800
MRDVIWDLEY VLQLQMMTNR REAHEEDSTA INSGGSLVAP RLMVSDSFST
810 820 830
NSIFQNGDES KNRFGFTDSS ETRVFSQLKI SDAR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC002391 Genomic DNA Translation: AAB87113.1 CP002685 Genomic DNA Translation: AEC07428.1 |
PIRi | T00512 |
RefSeqi | NP_179901.1, NM_127884.4 |
Genome annotation databases
EnsemblPlantsi | AT2G23200.1; AT2G23200.1; AT2G23200 |
GeneIDi | 816852 |
Gramenei | AT2G23200.1; AT2G23200.1; AT2G23200 |
KEGGi | ath:AT2G23200 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC002391 Genomic DNA Translation: AAB87113.1 CP002685 Genomic DNA Translation: AEC07428.1 |
PIRi | T00512 |
RefSeqi | NP_179901.1, NM_127884.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 2205, 2 interactors |
IntActi | O22187, 2 interactors |
STRINGi | 3702.AT2G23200.1 |
PTM databases
iPTMneti | O22187 |
Proteomic databases
PaxDbi | O22187 |
PRIDEi | O22187 |
ProteomicsDBi | 243060 |
Genome annotation databases
EnsemblPlantsi | AT2G23200.1; AT2G23200.1; AT2G23200 |
GeneIDi | 816852 |
Gramenei | AT2G23200.1; AT2G23200.1; AT2G23200 |
KEGGi | ath:AT2G23200 |
Organism-specific databases
Araporti | AT2G23200 |
TAIRi | locus:2058636, AT2G23200 |
Phylogenomic databases
eggNOGi | KOG1187, Eukaryota |
HOGENOMi | CLU_000288_42_1_1 |
InParanoidi | O22187 |
OMAi | VNIDEGR |
OrthoDBi | 684563at2759 |
PhylomeDBi | O22187 |
Miscellaneous databases
PROi | PR:O22187 |
Gene expression databases
ExpressionAtlasi | O22187, baseline and differential |
Genevisiblei | O22187, AT |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR024788, Malectin-like_Carb-bd_dom IPR000719, Prot_kinase_dom IPR017441, Protein_kinase_ATP_BS IPR001245, Ser-Thr/Tyr_kinase_cat_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF12819, Malectin_like, 1 hit PF07714, PK_Tyr_Ser-Thr, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS00107, PROTEIN_KINASE_ATP, 1 hit PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Y2232_ARATH | |
Accessioni | O22187Primary (citable) accession number: O22187 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 13, 2009 |
Last sequence update: | January 1, 1998 | |
Last modified: | April 7, 2021 | |
This is version 143 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families