UniProtKB - O21946 (SSB_BPS14)
Single-stranded DNA-binding protein
32
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 65 | ZincBy similarity | 1 | |
Metal bindingi | 78 | ZincBy similarity | 1 | |
Metal bindingi | 88 | ZincBy similarity | 1 | |
Metal bindingi | 91 | ZincBy similarity | 1 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- single-stranded DNA binding Source: InterPro
GO - Biological processi
- DNA recombination Source: UniProtKB-KW
- DNA repair Source: UniProtKB-KW
- DNA replication Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding, Repressor |
Biological process | DNA damage, DNA recombination, DNA repair, DNA replication, Viral DNA replication |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Recommended name: Single-stranded DNA-binding proteinShort name: SSB protein Alternative name(s): Gp32 Helix-destabilizing protein |
Gene namesi | Name:32 Synonyms:ssb |
Organismi | Escherichia phage SV14 (Bacteriophage SV14) |
Taxonomic identifieri | 47488 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Myoviridae › Tevenvirinae › Tequatrovirus |
Virus hosti | Enterobacteriaceae [TaxID: 543] |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000165064 | 1 – ›113 | Single-stranded DNA-binding proteinAdd BLAST | ›113 |
Interactioni
Subunit structurei
Homodimer in the absence of DNA, monomer when binding DNA.
Interacts with the DNA helicase assembly protein; a ternary complex between the helicase assembly protein, the single-stranded DNA-binding protein and ssDNA is an obligatory intermediate in the helicase loading mechanism. Part of the replicase complex that includes the DNA polymerase, the polymerase clamp, the clamp loader complex, the single-stranded DNA binding protein, the primase, the DnaB-like SF4 replicative helicase and the helicase assembly factor.
Interacts (via C-terminus) with the viral SF1 dDA helicase.
Interacts with the viral SF2 UvsW repair helicase.
By similarityFamily & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 3 – 7 | LASTBy similarity | 5 |
Domaini
Sequence similaritiesi
Family and domain databases
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR012339, Phage_T4_Gp32_ssDNA-bd |
Pfami | View protein in Pfam PF08804, gp32, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
i Sequence
Sequence statusi: Fragment.
10 20 30 40 50
MFKRKSTAEL AAQMAKLAGN KGGFSSEDKG EWKLKLDNAG NGQAVIRFLP
60 70 80 90 100
SKNDEQAPFA ILVNHGFKKN GKWYIENCSS THGDYDSCPV CQYISKNDLY
110
NTDNKEYGLV KRK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 113 | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF033318 Genomic DNA Translation: AAB87484.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF033318 Genomic DNA Translation: AAB87484.1 |
3D structure databases
SMRi | O21946 |
ModBasei | Search... |
Family and domain databases
InterProi | View protein in InterPro IPR012340, NA-bd_OB-fold IPR012339, Phage_T4_Gp32_ssDNA-bd |
Pfami | View protein in Pfam PF08804, gp32, 1 hit |
SUPFAMi | SSF50249, SSF50249, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SSB_BPS14 | |
Accessioni | O21946Primary (citable) accession number: O21946 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 15, 1998 |
Last sequence update: | January 1, 1998 | |
Last modified: | April 7, 2021 | |
This is version 68 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |