UniProtKB - O19626 (O19626_HUMAN)
Protein
Submitted name:
HLA-B35
Gene
B-3501
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: HLA-B35Imported |
Gene namesi | Name:B-3501Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | Sequence analysisAdd BLAST | 24 | |
ChainiPRO_5004157553 | 25 – 322 | Sequence analysisAdd BLAST | 298 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 125 ↔ 188 | Combined sources | ||
Disulfide bondi | 227 ↔ 283 | Combined sources |
Keywords - PTMi
Disulfide bondARBA annotation, GlycoproteinARBA annotationProteomic databases
PeptideAtlasi | O19626 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 209 – 295 | Ig-likeInterPro annotationAdd BLAST | 87 |
Sequence similaritiesi
Belongs to the MHC class I family.UniRule annotation
Keywords - Domaini
SignalSequence analysisARBA annotationFamily and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.30.500.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set IPR011161, MHC_I-like_Ag-recog IPR037055, MHC_I-like_Ag-recog_sf IPR011162, MHC_I/II-like_Ag-recog IPR001039, MHC_I_a_a1/a2 |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit PF00129, MHC_I, 1 hit |
PRINTSi | PR01638, MHCCLASSI |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF54452, SSF54452, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
i Sequence
Sequence statusi: Fragment.
O19626-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRVTAPRTVL LLLWGAVALT ETWAGSHSMR YFYTAMSRPG RGEPRFIAVG
60 70 80 90 100
YVDDTQFVRF DSDAASPRTE PRAPWIEQEG PEYWDRNTQI FKTNTQTYRE
110 120 130 140 150
SLRNLRGYYN QSEAGSHIIQ RMYGCDLGPD GRLLRGHDQS AYDGKDYIAL
160 170 180 190 200
NEDLSSWTAA DTAAQITQRK WEAARVAEQL RAYLEGLCVE WLRRYLENGK
210 220 230 240 250
ETLQRADPPK THVTHHPVSD HEATLRCWAL GFYPAEITLT WQRDGEDQTQ
260 270 280 290 300
DTELVETRPA GDRTFQKWAA VVVPSGEEQR YTCHVQHEGL PKPLTLRWEP
310 320
SSQSTIPIVG IVAGLAVLAV VV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 322 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U11265 mRNA Translation: AAA19925.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U11265 mRNA Translation: AAA19925.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2CIK | X-ray | 1.75 | A | 25-300 | [»] | |
2FYY | X-ray | 1.50 | A | 25-300 | [»] | |
2FZ3 | X-ray | 1.90 | A | 25-300 | [»] | |
SMRi | O19626 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Proteomic databases
PeptideAtlasi | O19626 |
Family and domain databases
Gene3Di | 2.60.40.10, 1 hit 3.30.500.10, 1 hit |
InterProi | View protein in InterPro IPR007110, Ig-like_dom IPR036179, Ig-like_dom_sf IPR013783, Ig-like_fold IPR003006, Ig/MHC_CS IPR003597, Ig_C1-set IPR011161, MHC_I-like_Ag-recog IPR037055, MHC_I-like_Ag-recog_sf IPR011162, MHC_I/II-like_Ag-recog IPR001039, MHC_I_a_a1/a2 |
Pfami | View protein in Pfam PF07654, C1-set, 1 hit PF00129, MHC_I, 1 hit |
PRINTSi | PR01638, MHCCLASSI |
SMARTi | View protein in SMART SM00407, IGc1, 1 hit |
SUPFAMi | SSF48726, SSF48726, 1 hit SSF54452, SSF54452, 1 hit |
PROSITEi | View protein in PROSITE PS50835, IG_LIKE, 1 hit PS00290, IG_MHC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | O19626_HUMAN | |
Accessioni | O19626Primary (citable) accession number: O19626 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | January 1, 1998 |
Last sequence update: | January 1, 1998 | |
Last modified: | August 12, 2020 | |
This is version 119 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |