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Entry version 180 (18 Sep 2019)
Sequence version 1 (01 Jan 1998)
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Protein
Submitted name:

HLA class I antigen

Gene

HLA-C

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processImmunity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
HLA class I antigenImported
Submitted name:
HLA class I histocompatibility antigenImported
Submitted name:
HLA class I histocompatibility antigen, Cw-6 alpha chainImported
Submitted name:
HLA-C proteinImported
Submitted name:
MHC class I antigenImported
Submitted name:
MHC class I histocompatibility antigenImported
Submitted name:
MHC class I proteinImported
Submitted name:
Major histocompatibility complex, class I, CImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HLA-CImported
Synonyms:HLA-CwImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:4933 HLA-C

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei308 – 331HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane, MHC ISAAS annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501509674325 – 366Sequence analysisAdd BLAST342

Proteomic databases

ProteomicsDB human proteome resource

More...
ProteomicsDBi
48758

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini209 – 297Ig-likeInterPro annotationAdd BLAST89

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410II5V Eukaryota
ENOG4111K8F LUCA

Database of Orthologous Groups

More...
OrthoDBi
1390181at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 1 hit
3.30.500.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
IPR010579 MHC_I_a_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PF06623 MHC_I_C, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01638 MHCCLASSI

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00407 IGc1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50835 IG_LIKE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 54 potential isoforms that are computationally mapped.Show allAlign All

O19617-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRVMAPRALL LLLSGGLALT ETWACSHSMR YFDTAVSRPG RGEPRFISVG
60 70 80 90 100
YVDDTQFVRF DSDAASPRGE PRAPWVEQEG PEYWDRETQN YKRQAQADRV
110 120 130 140 150
SLRNLRGYYN QSEDGSHTLQ RMYGCDLGPD GRLLRGYDQS AYDGKDYIAL
160 170 180 190 200
NEDLRSWTAA DTAAQITQRK LEAARAAEQL RAYLEGTCVE WLRRYLENGK
210 220 230 240 250
ETLQRAEPPK THVTHHPLSD HEATLRCWAL GFYPAEITLT WQRDGEDQTQ
260 270 280 290 300
DTELVETRPA GDGTFQKWAA VVVPSGQEQR YTCHMQHEGL QEPLTLSWEP
310 320 330 340 350
SSQPTIPIMG IVAGLAVLVV LAVLGAVVTA MMCRRKSSGG KGGSCSQAAC
360
SNSAQGSDES LITCKA
Length:366
Mass (Da):40,711
Last modified:January 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0B9518E6AA77A609
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 54 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
P103211C07_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
P304991C01_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q299631C06_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
P305041C04_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
P042221C03_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q956041C17_HUMAN
HLA class I histocompatibility anti...
HLA-C D6S204, HLA-JY3, HLAC
372Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
P305011C02_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q070001C15_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
P305081C12_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q299601C16_HUMAN
HLA class I histocompatibility anti...
HLA-C HLAC
366Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
There are more potential isoformsShow all

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL662833 Genomic DNA No translation available.
BC033293 mRNA Translation: AAH33293.1
GQ472838 Genomic DNA Translation: ACV91118.1
GQ472839 Genomic DNA Translation: ACV91119.1
KU528607 Genomic DNA Translation: ALZ40822.1
KU319188 Genomic DNA Translation: ANG08604.1
KU319189 Genomic DNA Translation: ANG08605.1
KX649950 Genomic DNA Translation: ANZ73061.1
KY622045 Genomic DNA Translation: ASE99681.1
KY626050 Genomic DNA Translation: ASE99686.1
KY419402 Genomic DNA Translation: ASU50293.1
KY419403 Genomic DNA Translation: ASU50294.1
KY419404 Genomic DNA Translation: ASU50295.1
KY419405 Genomic DNA Translation: ASU50296.1
MF981006 Genomic DNA Translation: ATV81380.1
KY499646 Genomic DNA Translation: AUN50126.1
MG584060 Genomic DNA Translation: AUQ33504.1
MG701558 Genomic DNA Translation: AUQ33562.1
MG769793 Genomic DNA Translation: AUQ33682.1
MG747476 Genomic DNA Translation: AUZ98368.1
MG779942 Genomic DNA Translation: AVC68922.1
MG930617 Genomic DNA Translation: AVV62703.1
MG930622 Genomic DNA Translation: AVV62708.1
MG944953 Genomic DNA Translation: AVV63103.1
MG911201 Genomic DNA Translation: AWC68084.1
MH173509 Genomic DNA Translation: AWM62556.1
MH374096 Genomic DNA Translation: AWM63100.1
MH814709 Genomic DNA Translation: AXU24216.1
MH537760 Genomic DNA Translation: AXU93754.1
MH537761 Genomic DNA Translation: AXU93755.1
D83957 Genomic DNA Translation: BAA22206.1
BA000025 Genomic DNA Translation: BAB63310.1
AB774946 Genomic DNA Translation: BAN59792.1
HE793165 Genomic DNA Translation: CCG58319.1
HF565303 Genomic DNA Translation: CCP37718.1
HG794375 Genomic DNA Translation: CDK41184.1
HG794378 Genomic DNA Translation: CDK41187.1
LK021963 Genomic DNA Translation: CDQ51644.1
LN600112 Genomic DNA Translation: CEF48102.2
LN624510 Genomic DNA Translation: CEH11580.1
LN811470 Genomic DNA Translation: CEP25297.1
LN832568 Genomic DNA Translation: CQR91446.1
LN877368 Genomic DNA Translation: CUA55111.1
LN912841 Genomic DNA Translation: CUU97168.1
LN912851 Genomic DNA Translation: CUU97178.1
LN912882 Genomic DNA Translation: CUU97209.1
LN912964 Genomic DNA Translation: CUU97291.1
LN912965 Genomic DNA Translation: CUU97292.1
LN912966 Genomic DNA Translation: CUU97293.1
LN912967 Genomic DNA Translation: CUU97294.1
LN912968 Genomic DNA Translation: CUU97295.1
MH269357 Genomic DNA Translation: QAX33617.1
MH269358 Genomic DNA Translation: QAX33618.1
MH269359 Genomic DNA Translation: QAX33619.1
MH269360 Genomic DNA Translation: QAX33620.1
MK780765 Genomic DNA Translation: QCW64097.1
MK225295 Genomic DNA Translation: QDC33380.1
MK442082 Genomic DNA Translation: QDC33418.1
LT575524 Genomic DNA Translation: SBL08196.1
LT599302 Genomic DNA Translation: SBW38523.1
LT599310 Genomic DNA Translation: SBW38531.1
LT599317 Genomic DNA Translation: SBW38538.1
LT599328 Genomic DNA Translation: SBW38549.1
LT618799 Genomic DNA Translation: SCQ83615.1
LT627695 Genomic DNA Translation: SFV42124.1
LT898183 Genomic DNA Translation: SNQ25993.1
LT963220 Genomic DNA Translation: SOR74764.1
LT963259 Genomic DNA Translation: SOR74803.1
LT964794 Genomic DNA Translation: SOT92898.1
LT964813 Genomic DNA Translation: SOT92917.1
LT964820 Genomic DNA Translation: SOT92924.1
LT964841 Genomic DNA Translation: SOT92945.1
LT964849 Genomic DNA Translation: SOT92953.1
LT964853 Genomic DNA Translation: SOT92957.1
LT966226 Genomic DNA Translation: SOU90380.1
LT966290 Genomic DNA Translation: SOU90444.1
LT966291 Genomic DNA Translation: SOU90445.1
LT970872 Genomic DNA Translation: SOX29787.1
LT990031 Genomic DNA Translation: SPI58569.1
LS453233 Genomic DNA Translation: SPS67918.1
LS453256 Genomic DNA Translation: SPS67946.1
LS453267 Genomic DNA Translation: SPS67963.1
LS992350 Genomic DNA Translation: SYY42650.1
LS992433 Genomic DNA Translation: SYY42733.1
LR596415 Genomic DNA Translation: VUE12350.1

NCBI Reference Sequences

More...
RefSeqi
NP_001229971.1, NM_001243042.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000424832; ENSP00000414063; ENSG00000233841

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3107

UCSC genome browser

More...
UCSCi
uc011fcf.3 human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662833 Genomic DNA No translation available.
BC033293 mRNA Translation: AAH33293.1
GQ472838 Genomic DNA Translation: ACV91118.1
GQ472839 Genomic DNA Translation: ACV91119.1
KU528607 Genomic DNA Translation: ALZ40822.1
KU319188 Genomic DNA Translation: ANG08604.1
KU319189 Genomic DNA Translation: ANG08605.1
KX649950 Genomic DNA Translation: ANZ73061.1
KY622045 Genomic DNA Translation: ASE99681.1
KY626050 Genomic DNA Translation: ASE99686.1
KY419402 Genomic DNA Translation: ASU50293.1
KY419403 Genomic DNA Translation: ASU50294.1
KY419404 Genomic DNA Translation: ASU50295.1
KY419405 Genomic DNA Translation: ASU50296.1
MF981006 Genomic DNA Translation: ATV81380.1
KY499646 Genomic DNA Translation: AUN50126.1
MG584060 Genomic DNA Translation: AUQ33504.1
MG701558 Genomic DNA Translation: AUQ33562.1
MG769793 Genomic DNA Translation: AUQ33682.1
MG747476 Genomic DNA Translation: AUZ98368.1
MG779942 Genomic DNA Translation: AVC68922.1
MG930617 Genomic DNA Translation: AVV62703.1
MG930622 Genomic DNA Translation: AVV62708.1
MG944953 Genomic DNA Translation: AVV63103.1
MG911201 Genomic DNA Translation: AWC68084.1
MH173509 Genomic DNA Translation: AWM62556.1
MH374096 Genomic DNA Translation: AWM63100.1
MH814709 Genomic DNA Translation: AXU24216.1
MH537760 Genomic DNA Translation: AXU93754.1
MH537761 Genomic DNA Translation: AXU93755.1
D83957 Genomic DNA Translation: BAA22206.1
BA000025 Genomic DNA Translation: BAB63310.1
AB774946 Genomic DNA Translation: BAN59792.1
HE793165 Genomic DNA Translation: CCG58319.1
HF565303 Genomic DNA Translation: CCP37718.1
HG794375 Genomic DNA Translation: CDK41184.1
HG794378 Genomic DNA Translation: CDK41187.1
LK021963 Genomic DNA Translation: CDQ51644.1
LN600112 Genomic DNA Translation: CEF48102.2
LN624510 Genomic DNA Translation: CEH11580.1
LN811470 Genomic DNA Translation: CEP25297.1
LN832568 Genomic DNA Translation: CQR91446.1
LN877368 Genomic DNA Translation: CUA55111.1
LN912841 Genomic DNA Translation: CUU97168.1
LN912851 Genomic DNA Translation: CUU97178.1
LN912882 Genomic DNA Translation: CUU97209.1
LN912964 Genomic DNA Translation: CUU97291.1
LN912965 Genomic DNA Translation: CUU97292.1
LN912966 Genomic DNA Translation: CUU97293.1
LN912967 Genomic DNA Translation: CUU97294.1
LN912968 Genomic DNA Translation: CUU97295.1
MH269357 Genomic DNA Translation: QAX33617.1
MH269358 Genomic DNA Translation: QAX33618.1
MH269359 Genomic DNA Translation: QAX33619.1
MH269360 Genomic DNA Translation: QAX33620.1
MK780765 Genomic DNA Translation: QCW64097.1
MK225295 Genomic DNA Translation: QDC33380.1
MK442082 Genomic DNA Translation: QDC33418.1
LT575524 Genomic DNA Translation: SBL08196.1
LT599302 Genomic DNA Translation: SBW38523.1
LT599310 Genomic DNA Translation: SBW38531.1
LT599317 Genomic DNA Translation: SBW38538.1
LT599328 Genomic DNA Translation: SBW38549.1
LT618799 Genomic DNA Translation: SCQ83615.1
LT627695 Genomic DNA Translation: SFV42124.1
LT898183 Genomic DNA Translation: SNQ25993.1
LT963220 Genomic DNA Translation: SOR74764.1
LT963259 Genomic DNA Translation: SOR74803.1
LT964794 Genomic DNA Translation: SOT92898.1
LT964813 Genomic DNA Translation: SOT92917.1
LT964820 Genomic DNA Translation: SOT92924.1
LT964841 Genomic DNA Translation: SOT92945.1
LT964849 Genomic DNA Translation: SOT92953.1
LT964853 Genomic DNA Translation: SOT92957.1
LT966226 Genomic DNA Translation: SOU90380.1
LT966290 Genomic DNA Translation: SOU90444.1
LT966291 Genomic DNA Translation: SOU90445.1
LT970872 Genomic DNA Translation: SOX29787.1
LT990031 Genomic DNA Translation: SPI58569.1
LS453233 Genomic DNA Translation: SPS67918.1
LS453256 Genomic DNA Translation: SPS67946.1
LS453267 Genomic DNA Translation: SPS67963.1
LS992350 Genomic DNA Translation: SYY42650.1
LS992433 Genomic DNA Translation: SYY42733.1
LR596415 Genomic DNA Translation: VUE12350.1
RefSeqiNP_001229971.1, NM_001243042.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

ProteomicsDBi48758

Protocols and materials databases

The DNASU plasmid repository

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DNASUi
3107
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000424832; ENSP00000414063; ENSG00000233841
GeneIDi3107
UCSCiuc011fcf.3 human

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
3107
HGNCiHGNC:4933 HLA-C

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410II5V Eukaryota
ENOG4111K8F LUCA
OrthoDBi1390181at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
HLA-C human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
3107

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.30.500.10, 1 hit
InterProiView protein in InterPro
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003597 Ig_C1-set
IPR011161 MHC_I-like_Ag-recog
IPR037055 MHC_I-like_Ag-recog_sf
IPR011162 MHC_I/II-like_Ag-recog
IPR001039 MHC_I_a_a1/a2
IPR010579 MHC_I_a_C
PfamiView protein in Pfam
PF07654 C1-set, 1 hit
PF00129 MHC_I, 1 hit
PF06623 MHC_I_C, 1 hit
PRINTSiPR01638 MHCCLASSI
SMARTiView protein in SMART
SM00407 IGc1, 1 hit
SUPFAMiSSF48726 SSF48726, 1 hit
SSF54452 SSF54452, 1 hit
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO19617_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O19617
Secondary accession number(s): A0A090KMD8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: January 1, 1998
Last sequence update: January 1, 1998
Last modified: September 18, 2019
This is version 180 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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